Nitrosylation of ethyl esters of ?-(3,3-dimethyl-1,2,3,4-tetrahydro-1-isoquinolylidene) carboxylic acids

Author(s):  
V. S. Shklyaev ◽  
B. B. Aleksandrov ◽  
M. S. Gavrilov
1970 ◽  
Vol 48 (11) ◽  
pp. 1689-1697 ◽  
Author(s):  
M. W. Roomi ◽  
S. F. MacDonald

Ethyl esters of 2-alkyl- and 2,4-dialkylpyrrole-3-carboxylic acids are obtained generally by extensions of the Hantzsch synthesis, benzyl and t-butyl esters when the 2-alkyl group is methyl. Hemopyrrole is obtained from butanal and ethyl acetoacetate in three steps. Pyrroles bearing higher alkyl groups or carbobenzoxy groups are reductively alkylated like the corresponding methylpyrroles and carbethoxy derivatives; t-butyl esters do not survive.


1990 ◽  
Vol 53 (1) ◽  
pp. 77-85 ◽  
Author(s):  
A.L. Zanocco ◽  
E.A. Soto ◽  
E.A. Lissi ◽  
J.C. Scaiano

2001 ◽  
Vol 111 (2) ◽  
pp. 115-128 ◽  
Author(s):  
Takashi Abe ◽  
Hajime Baba ◽  
Kunio Okuhara ◽  
Haruhiko Fukaya

1989 ◽  
Vol 54 (8) ◽  
pp. 2181-2189 ◽  
Author(s):  
Stanislav Rádl ◽  
Viktor Zikán

1,4-Dihydro-4-oxoquinoline-3-carboxylic acids VIIIc and VIIId were prepared via their ethyl esters VIIIa and VIIIb, which were obtained by a direct arylation of ethyl 7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate (VIa). When treated with piperazine or N-methylpiperazine compound VIIId yields VIIIe or VIIIf, respectively. Reduction of VIIId, VIIIe, and VIIIf with ferrous sulfate yields VIIIg, VIIIh, and VIIIi, respectively. Diazotization and introduction of fluorine into VIIIg using hydrogen fluoride-pyridine yields VIIIj. The compounds prepared were tested for their antimicrobial activity in vitro.


2011 ◽  
Vol 85 (9) ◽  
pp. 1516-1527 ◽  
Author(s):  
L. E. Agafonova ◽  
R. M. Varushchenko ◽  
A. I. Druzhinina ◽  
O. V. Polyakova ◽  
Yu. S. Kolesov

Author(s):  
A. A. Abduvakhabov ◽  
M. A. Azlyarova ◽  
A. P. Brestkin ◽  
E. B. Maizel ◽  
E. V. Rozengart ◽  
...  

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