Reaction of acetyl chloride with borylphosphinoethene

1989 ◽  
Vol 38 (4) ◽  
pp. 882-882 ◽  
Author(s):  
A. S. Balueva ◽  
O. A. Erastov ◽  
T. A. Zyablikova
Keyword(s):  
Acetyl Chloride

scholarly journals Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group

2004 ◽  
Vol 1 (2) ◽  
pp. 93-98 ◽  
Author(s):  
H. S. Patel ◽  
H. D. Desai ◽  
H. J. Mistry
Keyword(s):  
Antimicrobial Activity ◽  
Acetyl Chloride ◽  
Condensation Reaction ◽  
Piperazine Derivatives ◽  
Substituted Piperazine

NovelN-substituted piperazine derivatives containing sulfonyloxy aniline moiety have been prepared. The various 4-sulfonyloxy aniline (SA) derivatives (2a-h) have been prepared by the condensation reaction ofN-Acetyl Sulfanilyl chloride (ASC) and sodium phenates followed by hydrolysis. The SA derivatives are then reacted with chloro acetyl chloride to give corresponding (N-Chloroacetyl) derivatives (3a-h). These derivatives are then reacted withN-phenyl piperazine to yield the corresponding piperazine derivatives (4a-h).

The system aluminum chloride-acetyl chloride in sulfur dioxide solvent

1982 ◽  
Vol 47 (6) ◽  
pp. 1005-1007 ◽  
Author(s):  
Boris Glavincevski ◽  
Sydney Brownstein
Keyword(s):  
Sulfur Dioxide ◽  
Aluminum Chloride ◽  
Acetyl Chloride

Friedel-Crafts acylation of antiaromatic norcorrole: electronic and steric modulation of the paratropic current

2021 ◽  
Author(s):  
Sha Li ◽  
Oskar Smaga ◽  
Yahan Sun ◽  
Xiaofang Li ◽  
Miłosz Pawlicki ◽  
...  
Keyword(s):  
Room Temperature ◽  
Acetyl Chloride ◽  
Acyl Chlorides

Acyl chlorides react with norcorrolatonickle(II) in dichloromethane in the presence of AlCl3 at room temperature affording two isomeric monoketone derivatives in moderate yields. For acetyl chloride, also diketones were detected...

SYNTHESIS OF NOVEL QUINAZOLIN-4(3H)-ONYL AZETIDINONES AS POTENTIAL ANTICONVULSANT AGENTS

INDIAN DRUGS ◽  
2017 ◽  
Vol 54 (11) ◽  
pp. 22-27
Author(s):  
A. Singh ◽  
Keyword(s):  
Magnetic Resonance ◽  
Acute Toxicity ◽  
Anticonvulsant Activity ◽  
Proton Magnetic Resonance ◽  
Acetyl Chloride ◽  
Mass Analysis ◽  
Substituted Anilines ◽  
Anticonvulsant Agents

A series of 4-(substituted aryl)- 1- [2’- methyl-6’- substituted anilino quinazolinon-4’-(3’H)-onyl ] -3- chloroazetidin- 2-ones 14-25 have been synthesized by addition of substituted anilines to 4-(substituted aryl)- 1- [2’- methyl-6’- bromoquinazolinon-4’-(3’H)-onyl ] -3- chloro- azetidin-2-ones 8-13 which in turn were prepared by the cycloaddition of triethylamine in dioxane to 3-(N-substituted benzylidene amino phenyl amido )-2-methyl-6-bromoquinazolin-4(3H)-ones 2-7 in presence of acetyl chloride. These compounds were screened for anticonvulsant activity and acute toxicity. Compound 4-(substituted aryl)- 1- [2’- methyl-6’- substituted anilino quinazolinon-4’-(3’H) – onyl ] -3- chloro-azetidinone showed most potent activity. The structure of all the synthesized compounds were delineated by elemental (C, H, N ) and spectra (IR, proton magnetic resonance and mass ) analysis.

Deacetylation of Thioacetate Using Acetyl Chloride in Methanol.

ChemInform ◽  
2006 ◽  
Vol 37 (46) ◽  
Author(s):  
Neera Tewari ◽  
Hashim Nizar ◽  
Avinash Mane ◽  
Vinod George ◽  
Mohan Prasad
Keyword(s):  
Acetyl Chloride

scholarly journals Design, Synthesis, Antimicrobial, and Antioxidant Activities of Novel-{4, 5-(substituted diphenyl)-4H-1, 2, 4-triazol-3-ylthio} Acetyl Chloride

2017 ◽  
Vol 15 (2) ◽  
pp. 157-167
Author(s):  
Prabhakar Kumar VERMA ◽  
Mukesh KUMAR ◽  
Nelam MALIK ◽  
Priyanka DHIMAN ◽  
Anurag KHATAHAR
Keyword(s):  
Free Radical ◽  
Acetyl Chloride ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Biologically Active ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Standard Drug

A series of 20 new biologically active derivatives of 2-{4, 5-(substituted diphenyl)-4H-1,2,4-triazol-3-ylthio}acetyl chloride has been synthesized, with the aim to investigate antimicrobial, free radical scavenging activity. All the synthesized compounds were characterized by spectroscopic data and elemental analysis. The final compounds were tested for antibacterial activity against Gram-positive bacteria: Staphylococcus aureus MTCC 3160, Bacillus subtilis MTCC 441; Gram-negative bacteria: Escherichia coli MTCC 443, and, for antifungal activity, against Candida albicans MTCC 227 and Aspergillus niger MTCC 281, taking ciprofloxacin as antibacterial and fluconazole as antifungal standard drugs. Compound 7a6 was found to be the most effective antibacterial (MIC = 3.12 µg/ml), and compounds 7a2 and 7d1 (MIC = 3.12 and 6.25 µg/ml) had the most effective antifungal effects on the selected strains, as compared to the standard drugs. The results of antioxidant studies revealed that compound 7b1 was found to be most active antioxidant, with 40.4±0.687 µg/ml, and compounds 7b3, 7d7, and 7d4 also showed promising free radical scavenging activity, as compared with the standard drug ascorbic acid.

scholarly journals Synthesis and Antioxidant Properties of Novel 2-(2,4-Dioxothiazolidin-5-ylidene)-Acetamides Containing 1,3,4-Thia/Oxadiazole Moieties

2021 ◽  
Vol 12 (5) ◽  
pp. 6710-6722
Keyword(s):  
Ascorbic Acid ◽  
Acetyl Chloride ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Scavenging Effect ◽  
Highly Active ◽  
Ethanol Medium ◽  
Ic50 Value ◽  
Radical Scavenging Ability

A series of novel 1,3,4-thia(oxa)diazole substituted 2-(2,4-dioxothiazolidine-5-ylidene)-acetamides 3a-c, 4 and 5a-k have been synthesized following the acylation reaction of 2-amino-5-aryl-1,3,4-oxadiazoles, 5-amino-1,3,4-thiadiazole-2-thiol and it’s S-alkylated derivatives with 2-(2,4-dioxothiazolidine-5-ylidene)acetyl chloride in dioxane medium. The functionalization of compounds 3b, 3c, 5d and 5e was carried out on their N3 position under N-alkylation conditions with N-aryl-2-chloroacetamides in DMF/ethanol medium yielded the corresponding 2,4-dioxothiazolidine-3,5-diacetic acid diamides 6a-e and 7a-b. The structures of target compounds were confirmed by using 1H NMR spectroscopy and elemental analysis. The antioxidant activity evaluation in vitro of the synthesized compounds was performed by the method of scavenging effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. As a result, the highly active compound 4, namely 2-(2,4-dioxothiazolidin-5-ylidene)-N-(5-mercapto-[1,3,4]thiadiazol-2-yl)acetamide was found to be the most efficient candidate among all compounds with a radical scavenging ability of 88.9%, which was comparable that for ascorbic acid (92.7%). The experimentally calculated IC50 value of 43.1 µM for compound 4 was lower than for ascorbic acid (50.5 µM).

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