Immunoelectron microscopical localization of a circulating antigen in the excretory system ofSchistosoma mansoni

1995 ◽  
Vol 81 (5) ◽  
pp. 375-381 ◽  
Author(s):  
J. J. P. M. Bogers ◽  
H. A. M. Nibbeling ◽  
E. A. E. Van Marck ◽  
A. M. Deelder
Keyword(s):  
Excretory System ◽  
Circulating Antigen ◽  
Microscopical Localization

scholarly journals Assessing eighth graders’ scientific explanation on human excretory system

2021 ◽  
Author(s):  
Isna Istikhanif Farida ◽  
A. M. Setiawan ◽  
Muntholib Muntholib
Keyword(s):  
Scientific Explanation ◽  
Eighth Graders ◽  
Excretory System

Experimental Schistosoma bovis infection in goats. Circulating antigen and antibody responses to egg and adult worm antigens during infection and following treatment with praziquantel

Parasitology ◽  
1996 ◽  
Vol 113 (4) ◽  
pp. 367-375 ◽  
Author(s):  
M. V. Johansen ◽  
Y. Fillié ◽  
J. Monrad ◽  
N. Ø. Christensen ◽  
A. Deelder
Keyword(s):  
Adult Worm ◽  
Specific Antibody ◽  
Post Treatment ◽  
Antibody Responses ◽  
Antibody Detection ◽  
Faecal Samples ◽  
Schistosoma Bovis ◽  
Worm Recovery ◽  
Circulating Antigen ◽  
Positive Correlations

SUMMARYCirculating antigen levels and antibody responses in Schistosoma bovis-infected West African Dwarf goats were evaluated during infection and following treatment with praziquantel (60 mg/kg) 13 weeks post-infection. One day, 1 week and 4 weeks post-treatment, subgroups of goats were sacrificed and perfused for worm recovery. For comparison, parasite-free control animals were included. Blood and faecal samples were collected biweekly. Two gut-associated schistosome antigens, circulating cathodic and circulating anodic antigen (CCA and CAA) and 3 specific antibody responses (total Ig, IgG and IgM) were measured. For specific antibody detection, crude S. bovis adult worm and egg homogenates were used. The level of CCA in the infected groups was significantly elevated from the time of onset of egg excretion onwards. However, following treatment, the CCA litres dropped to control levels within 1 week post-treatment. Strong positive correlations were found between CCA levels and worm counts and faecal egg counts during peak egg excretion. The correlations of CAA and specific antibody litres to egg and worm counts were poor. The antibody responses were all significantly elevated in the infected goats during patency, but only marginally affected by the treatment. Hence, CCA proved to be superior by correlating strongly to the level of infection and by being a sensitive indicator of the effect of treatment.

Morphology of the Excretory System of Hysterothylacium haze (Nematoda: Anisakidae: Raphidascaridinae)

1989 ◽  
Vol 75 (5) ◽  
pp. 812 ◽  
Author(s):  
Tomoyoshi Yoshinaga ◽  
Kazuo Ogawa ◽  
Hisatsugu Wakabayashi
Keyword(s):  
Excretory System

scholarly journals Lacrimal excretory system sequelae in patients treated for leishmaniasis

2006 ◽  
Vol 69 (3) ◽  
pp. 333-337
Author(s):  
Erika Hoyama ◽  
Silvana Artioli Schellini ◽  
Hamilton Ometo Stolf ◽  
Vitor Nakajima
Keyword(s):  
Excretory System

scholarly journals Atypical disseminated cutaneous histoplasmosis in an immunocompetent child, caused by an "aberrant" variant of Histoplasma capsulatum var. capsulatum

1999 ◽  
Vol 41 (3) ◽  
pp. 195-202 ◽  
Author(s):  
Carlos da Silva LACAZ ◽  
Gilda Maria Barbaro DEL NEGRO ◽  
Mônica Scarpelli Martinelli VIDAL ◽  
Elisabeth Maria HEINS-VACCARI ◽  
Roseli Freitas dos SANTOS ◽  
...  
Keyword(s):  
Histoplasma Capsulatum ◽  
Complement Fixation ◽  
Double Immunodiffusion ◽  
Granulomatous Reaction ◽  
Cutaneous Lesions ◽  
Biopsy Material ◽  
Specific Staining ◽  
Hyperimmune Serum ◽  
Circulating Antigen ◽  
Immunoenzymatic Assay

A case of atypical disseminated cutaneous histoplasmosis in a five-year old, otherwise healthy child, native and resident in São Paulo metropolitan area is reported. Cutaneous lesions were clinically atypical. Histologic examination disclosed a granulomatous reaction but no fungal structures could be demonstrated by specific staining nor by immunohistochemical reaction. The fungus was isolated from biopsy material on two different occasions, confirming diagnosis of an unusual fungal infection. The fungus, originally thought to be a Sepedonium sp. due to the large sized, hyaline or brownish colored tuberculated macroconidia and to lack of dimorphism (yeast form at 37 °C) produce H and M antigens, visualized by the immunodiffusion with rabbit anti-Histoplasma capsulatum hyperimmune serum. Patient’s serum sample was non reactive with H. capsulatum antigen by immunodiffusion, counterimmunoelectrophoresis and complement fixation tests, and immunoenzymatic assay failed to detect the specific circulating antigen. This serum was tested negative by double immunodiffusion when antigen obtained from one of the isolated samples was used. Both cultures were sent to Dr. Leo Kaufman, Ph.D. (Mycoses Immunodiagnostic Laboratory, CDC-Atlanta/USA), who identified them as H. capsulatum by the exoantigen and gen-probe tests. Both clinic and mycologic characteristics of the present case were atypical, suggesting the fungus isolated is an “aberrant variant” of H. capsulatum var. capsulatum, as described by SUTTON et al. in 199719. Treatment with itraconazole 100 mg/day led to cure within 90 days

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