Function and energy metabolism of isolated hearts obtained from hyperthyroid spontaneously hypertensive rats (SHR)

1993 ◽  
Vol 119 (1-2) ◽  
pp. 43-50 ◽  
Author(s):  
M. Heckmann ◽  
S. Lortet ◽  
J. Aussedat ◽  
A. Ray ◽  
A. Rossi ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Isolated Hearts

Age changes in enzymes of neuronal and microvascular energy metabolism in the brain of spontaneously hypertensive rats

1990 ◽  
Vol 109 (5) ◽  
pp. 682-685
Author(s):  
V. A. Sorokoumov ◽  
Yu. Ya. Kislyakov ◽  
E. L. Pugacheva ◽  
E. R. Barantsevich ◽  
V. A. Grantyn'
Keyword(s):  
Energy Metabolism ◽  
Spontaneously Hypertensive Rats ◽  
Age Changes ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
The Brain

Age-related increase in the incidence of ventricular arrhythmias in isolated hearts from spontaneously hypertensive rats

1989 ◽  
Vol 3 (2) ◽  
pp. 163-169 ◽  
Author(s):  
Marco Pahor ◽  
Pietro Lo Giudice ◽  
Roberto Bernabei ◽  
Marco Di Gennaro ◽  
Licia Pacifici ◽  
...  
Keyword(s):  
Ventricular Arrhythmias ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Isolated Hearts ◽  
Age Related ◽  
Related Increase

scholarly journals Effects of Aerobic Exercise on Energy Metabolism in the Hypertensive Rat Heart

2001 ◽  
Vol 81 (4) ◽  
pp. 1006-1017 ◽  
Author(s):  
Tanya L Kinney LaPier ◽  
Kenneth J Rodnick
Keyword(s):  
Blood Pressure ◽  
Energy Metabolism ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Spontaneously Hypertensive Rats ◽  
Aerobic Exercise Training ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Cardiac Energy Metabolism ◽  
Cardiac Energy

AbstractBackground and Purpose. In order to explore the possible effects of physical therapy interventions on patients with hypertension, we evaluated the effects of aerobic exercise training on myocardial energy metabolism in an animal model of hypertension. Subjects. We used 36 female spontaneously hypertensive rats (rats with genetically induced hypertension) and 12 normotensive Wistar-Kyoto rats. Methods. The normotensive rats were sedentary and formed the CONsed group. The spontaneously hypertensive rats were randomly divided into 3 experimental groups (12 rats per group). Hypertensive rats that were sedentary formed the HTNsed group, those that received 8 weeks of exercise training formed the HTN×8 group, and those that received 16 weeks of exercise training formed the HTN×16 group. We measured systolic blood pressure, heart wet weight, maximal activities of cardiac energy metabolism enzymes, glucose transporter content, and total concentrations of protein, glycogen, and triglyceride. Results. Systolic blood pressure was greater than 200 mm Hg in the CONsed group at the time of testing. Exercise training modestly (∼11–18 mm Hg) lowered blood pressure in the HTN×8 and HTN×16 groups. Fatty acid enzyme activity was greater in the CONsed group than in the HTNsed and HTN×8 groups, but activity was roughly equivalent between the CONsed group and the HTN×16 group. Glucose enzyme activity was greater in the HTN×16 group than in the CONsed group and the HTNsed group. Intracellular glycogen concentration was greater in the HTN×8 group than in the HTNsed group. Discussion and Conclusion. Results of this study suggest that aerobic exercise training may help to normalize cardiac energy metabolism in mammals with hypertension.

Sign in / Sign up

Export Citation Format

Share Document