Primary culture of epithelial cells from the human mammary gland

1977 ◽  
Vol 3 (2) ◽  
pp. 571-573
Author(s):  
B. Allen Flaxman
Keyword(s):  
Mammary Gland ◽  
Epithelial Cells ◽  
Primary Culture ◽  
Human Mammary Gland

scholarly journals Ataxia Telangiectasia Mutated (ATM) Inhibition Transforms Human Mammary Gland Epithelial Cells

2010 ◽  
Vol 285 (17) ◽  
pp. 13092-13106 ◽  
Author(s):  
Stefano J. Mandriota ◽  
Raphaële Buser ◽  
Laurence Lesne ◽  
Christelle Stouder ◽  
Vincent Favaudon ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Epithelial Cells ◽  
Ataxia Telangiectasia ◽  
Ataxia Telangiectasia Mutated ◽  
Human Mammary Gland ◽  
Mammary Gland Epithelial Cells

Expression of glucose transporters in lactating human mammary gland epithelial cells

2000 ◽  
Vol 39 (5) ◽  
pp. 194-200 ◽  
Author(s):  
S. Obermeier ◽  
B. Hüselweh ◽  
H. Tinel ◽  
R.H.K. Kinne ◽  
C. Kunz
Keyword(s):  
Mammary Gland ◽  
Epithelial Cells ◽  
Glucose Transporters ◽  
Human Mammary Gland ◽  
Mammary Gland Epithelial Cells

The Human Mammary Gland Basement Membrane Is Integral to the Polarity of Luminal Epithelial Cells

1999 ◽  
Vol 247 (1) ◽  
pp. 267-278 ◽  
Author(s):  
Martin J. Slade ◽  
Rebecca C. Coope ◽  
Jennifer J. Gomm ◽  
R.Charles Coombes
Keyword(s):  
Mammary Gland ◽  
Epithelial Cells ◽  
Basement Membrane ◽  
Human Mammary Gland ◽  
Luminal Epithelial Cells

Comparative toxicity assessment of nano- and bulk-phase titanium dioxide particles on the human mammary gland in vitro

2020 ◽  
Vol 39 (11) ◽  
pp. 1475-1486
Author(s):  
S Kumar ◽  
A Hussain ◽  
B Bhushan ◽  
G Kaul
Keyword(s):  
Titanium Dioxide ◽  
Mammary Gland ◽  
Epithelial Cells ◽  
Mammary Epithelial Cells ◽  
Morphological Changes ◽  
Reactive Oxygen Species Generation ◽  
Mammary Epithelial ◽  
Bulk Phase ◽  
Human Mammary Gland

There is a major concern that exposure to titanium dioxide (TiO2) nanoparticles (NPs) can have degrading effects on human health as well as mammary gland because of the increased use in numerous sorts of nanotech-based health care and food merchandise. Also, there is a scarcity in NP toxicity studies on the mammary gland; therefore, the aim of the present study was to compare toxicity caused by nano- and bulk-phase TiO2 particles on the human mammary gland in vitro. In comparison to bulk-TiO2 particles, nano-TiO2 cause a significant ( p < 0.05) reduction in viability and increased reactive oxygen species generation in the human mammary epithelial cells after a dose- (1, 2, 5, 10, 20, 50, and 100 µg/mL) and time (6, 12, 24, and 48 h)-dependent exposure. Further, an increase in genotoxicity in the mammary epithelial cells was observed as percent tail DNA and comet area was increased significantly ( p < 0.05) at 12 h of exposure (10 and 100 µg/mL) with nano-TiO2. The scanning electron microscopic examination showed that a 50 µg/mL dose of both nano-TiO2 and bulk-TiO2 particles cause morphological changes and retarded growth pattern of mammary epithelial cells at 12 h. Moreover, a significant ( p < 0.05) increase in apoptosis at 10 µg/mL and necrosis at 50 µg/mL concentrations of nano-TiO2 in comparison to bulk-TiO2 was observed in mammary epithelial cells. Finally, we can conclude that the toxicity caused by nano-TiO2 particles on the human mammary gland cells was comparatively higher than the bulk-TiO2 particles.

scholarly journals Morphological and ultrastructural aspects of the cyclical changes of human mammary gland during the menstrual cycle

1994 ◽  
Vol 112 (2) ◽  
pp. 543-547 ◽  
Author(s):  
Afonso Celso Pinto Nazário ◽  
Manuel de Jesus Simões ◽  
Geraldo Rodrigues de Lima
Keyword(s):  
Mammary Gland ◽  
Menstrual Cycle ◽  
Epithelial Cells ◽  
Connective Tissue ◽  
Great Majority ◽  
Mammary Tissue ◽  
Secretory Phase ◽  
Proliferative Phase ◽  
Human Mammary Gland ◽  
Mitotic Figures

Analyzing the morphological and ultrastructural features of the mammary gland during the menstrual cycle, the authors observed that in the proliferative phase, the mammary gland consisted of few developed lobules and presented a relative absence of mitotic figures. In this phase, the great majority of the epithelial cells contained small, dark, irregular, rich heterochromatinic nuclei. The mammary stroma showed similar findings, presenting dense connective tissue with few enhanced fibroblasts. During the secretory phase, the lobules were well developed and mitotic figures were usually observed. In this phase, the great majority of the ephitelial cells presented clear voluminous, rich euchromatinic nuclei; the stroma consisted of fibroblasts with voluminous nuclei full of euchromatin. There are evident modifications of the mammary tissue according to the phase of the menstrual cycle. The morphological and ultrastructural modifications indicate higher metabolical and mitotic activities during the secretory phase.

The MHC class I related Fc receptor, FcRn, is expressed in the epithelial cells of the human mammary gland

2003 ◽  
Vol 64 (12) ◽  
pp. 1152-1159 ◽  
Author(s):  
Petru Cianga ◽  
Corina Cianga ◽  
Laurette Cozma ◽  
E.Sally Ward ◽  
Eugen Carasevici
Keyword(s):  
Mammary Gland ◽  
Epithelial Cells ◽  
Mhc Class I ◽  
Fc Receptor ◽  
Class I ◽  
Human Mammary Gland
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