In vitro cultivation of larval frog spinal cord explants

1976 ◽  
Vol 1 (4) ◽  
pp. 193-197 ◽  
Author(s):  
Emanuel D. Pollack ◽  
Judi Koves
Keyword(s):  
Spinal Cord ◽  
In Vitro Cultivation ◽  
Frog Spinal Cord

Electrophysiological study of the effects of cardiodilatin 1-16 on the frog spinal cord in vitro

1988 ◽  
Vol 247 (1) ◽  
pp. 109-112 ◽  
Author(s):  
A. De Santis ◽  
L. Cariello ◽  
A. Miralto ◽  
P. Russo ◽  
B. Tota
Keyword(s):  
Spinal Cord ◽  
Electrophysiological Study ◽  
Frog Spinal Cord

scholarly journals Enkephalin but not morphine modulates the motor activity in the frog spinal cord in vitro

1986 ◽  
Vol 83 (2) ◽  
pp. 245-251 ◽  
Author(s):  
Taklshi Suzuki ◽  
Jun-Ichiro Oka ◽  
Nobuo Nagano ◽  
Hideomi Fukuda
Keyword(s):  
Spinal Cord ◽  
Motor Activity ◽  
Frog Spinal Cord

Release of endogenous glutamate and aspartate from the frog spinal cord in vitro

1991 ◽  
Vol 195 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Maria Grazia Giovannini ◽  
Gary Lacey ◽  
Giancarlo Pepeu ◽  
Andrea Nistri
Keyword(s):  
Spinal Cord ◽  
Frog Spinal Cord

Effects of synthetic buffers on reflexes in the isolated frog spinal cord

1975 ◽  
Vol 229 (3) ◽  
pp. 831-837 ◽  
Author(s):  
RA Davidoff ◽  
ES Sears
Keyword(s):  
Spinal Cord ◽  
Dorsal Root ◽  
Ringer Solution ◽  
Membrane Properties ◽  
Buffer System ◽  
Bicarbonate Buffer ◽  
Frog Spinal Cord ◽  
Dorsal Root Reflex ◽  
Dorsal Root Potentials

Substitution of synthetic buffers (Tris, TES, HEPES, or 3,3-dimethylglutarate) for CO2-bicarbonate buffer in Ringer solution perfusing the isolated in vitro frog spinal cord preparation altered membrane properties and reflex activity. Perfusion with Ringer solution gassed with O2 and containing synthetic bu,fers consistently produced a depolarization of motoneurons and dorsal root fibers, decreased the amplitude (and usually the duration) of ventral and dorsal root potentials, and had variable effects on motoneuron and dorsal root reflex discharges. With Tris-Ringer these discharges decreased in amplitude; with Ringer containing one of the other synthetic buffers, these discharges were augmented. All changes were reversible when the cord was returned to bicarbonate-buffered Ringer aerated with 95% O2/5% CO2. The use of a combined buffer system-one containing a synthetic buffer and bicarbonate-induced smaller or minimal changes in bioelectric activity. At present the data are insufficient to allow firm conclusions concerning the mechanisms underlying these results; but it is evident 1) that changes in PCO2 and bicarbonate concentration and 2) that the pharmacological properties of synthetic buffers are important variables.

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