Dynamics of chemotactic peptide-induced superoxide generation by human monocytes

Inflammation ◽  
1987 ◽  
Vol 11 (2) ◽  
pp. 229-240 ◽  
Author(s):  
Edward J. Leonard ◽  
Amala Shenai ◽  
Alison Skeel
Keyword(s):  
Human Monocytes ◽  
Chemotactic Peptide ◽  
Superoxide Generation

scholarly journals Trp-Lys-Tyr-Met-Val-D-Met stimulates superoxide generation and killing of Staphylococcus aureus via phospholipase D activation in human monocytes

1999 ◽  
Vol 65 (2) ◽  
pp. 241-248 ◽  
Author(s):  
Yoe-Sik Bae ◽  
Seong-A Ju ◽  
Ji Yung Kim ◽  
Jeong Kon Seo ◽  
Suk Hwan Baek ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Phospholipase D ◽  
Human Monocytes ◽  
Superoxide Generation

scholarly journals Regulation of superoxide generation by myeloperoxidase during the respiratory burst of human neutrophils

1986 ◽  
Vol 237 (2) ◽  
pp. 601-604 ◽  
Author(s):  
S W Edwards ◽  
T F Swan
Keyword(s):  
Respiratory Burst ◽  
Cytochalasin B ◽  
Superoxide Radical ◽  
Human Neutrophils ◽  
Second Phase ◽  
Chemotactic Peptide ◽  
O2 Uptake ◽  
Superoxide Generation ◽  
Lower Magnitude

The role of myeloperoxidase in the regulation of the respiratory burst of human neutrophils activated by the chemotactic peptide (N-formyl-L-methionyl-L-leucyl-L-phenylalanine) plus cytochalasin B was determined by using anti-(human myeloperoxidase) antibody. The respiratory burst activated under these conditions consisted of an initial (1-2 min) phase with high rates of O2 uptake, luminol-dependent chemiluminescence and superoxide radical (O2-.) generation and a second, more sustained, phase of lower magnitude of chemiluminescence and O2 uptake: O2-. generation did not occur during this second phase. In cell suspensions stimulated in the presence of anti-(human myeloperoxidase) antibody, the magnitude of the initial phase of both O2 uptake and O2-. generation was unaffected, but these high rates were maintained over much longer periods than in control suspensions. It is therefore proposed that a product of myeloperoxidase normally regulates the duration of O2-. generation during the respiratory burst, possibly by inhibition of NADPH oxidase.

Potentiation of Chemotactic Peptide-Induced Superoxide Generation by CD38 Ligation in Human Myeloid Cell Lines

1997 ◽  
Vol 121 (5) ◽  
pp. 949-956 ◽  
Author(s):  
N. Tsujimoto ◽  
K. Kontain ◽  
S.-i. Inoue ◽  
S.-i. Hoshino ◽  
O. Hazeki ◽  
...  
Keyword(s):  
Cell Lines ◽  
Myeloid Cell ◽  
Chemotactic Peptide ◽  
Superoxide Generation

Chemotactic peptide-induced cytoplasmic pH changes in incubated human monocytes

1993 ◽  
Vol 53 (6) ◽  
pp. 673-678 ◽  
Author(s):  
John Bernardo ◽  
Lisa Brennan ◽  
Holly F. Brink ◽  
Maria F. Ortiz ◽  
Peter E. Newburger ◽  
...  
Keyword(s):  
Human Monocytes ◽  
Cytoplasmic Ph ◽  
Chemotactic Peptide ◽  
Ph Changes

Legionella pneumophila inhibits superoxide generation in human monocytes via the down-modulation of α and β protein kinase C isotypes

1994 ◽  
Vol 55 (3) ◽  
pp. 310-312 ◽  
Author(s):  
T. Jacob ◽  
J. C. Escallier ◽  
M. V. Sanguedolce ◽  
C. Chicheportiche ◽  
P. Bongrand ◽  
...  
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Legionella Pneumophila ◽  
Human Monocytes ◽  
Superoxide Generation ◽  
Kinase C ◽  
Β Protein

Superoxide generation by human monocytes and macrophages

1978 ◽  
Vol 4 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Stephen J. Weiss ◽  
Gerald W. King ◽  
Albert F. Lobuglio
Keyword(s):  
Human Monocytes ◽  
Superoxide Generation ◽  
Monocytes And Macrophages ◽  
Human Monocytes And Macrophages

Generation of Leukotrienes by Human Monocytes in Response to a Chemotactic Peptide

1986 ◽  
Vol 70 (s13) ◽  
pp. 55P-55P
Author(s):  
J.D. Williams ◽  
T.H. Lee ◽  
K.F. Austen
Keyword(s):  
Human Monocytes ◽  
Chemotactic Peptide
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