A double-blind comparison of once-daily metoprolol controlled-release and atenolol in the treatment of Chinese patients with mild to moderate hypertension

1995 ◽  
Vol 9 (3) ◽  
pp. 401-406 ◽  
Author(s):  
Ming-Fong Chen ◽  
Chi-Yu Yang ◽  
Wen-Jone Chen ◽  
Chii-Ming Lee ◽  
Chau-Chung Wu ◽  
...  
Keyword(s):  
Controlled Release ◽  
Moderate Hypertension ◽  
Chinese Patients ◽  
Double Blind ◽  
Once Daily ◽  
Blind Comparison

Experience with Once-Daily and Twice-Daily Slow-Release Frusemide in Hypertension

1982 ◽  
Vol 10 (4) ◽  
pp. 199-203 ◽  
Author(s):  
T A Vadász ◽  
Dev R Chadha
Keyword(s):  
Moderate Hypertension ◽  
Slow Release ◽  
Daily Administration ◽  
Double Blind ◽  
Release Formulation ◽  
Once Daily ◽  
Salt Diet ◽  
Low Salt ◽  
Blind Comparison ◽  
Dose Levels

Out of thirty-six patients with mild to moderate hypertension twenty-six patients completed a double-blind comparison of slow-release frusemide at two dose levels, and placebo. The two groups differed in their age pattern, baseline level of blood pressure and response to a low-salt diet during the wash-out/run-in period. Despite the lack of comparability of the two groups, firm clinical inferences could be drawn from the study. Seven of the eighteen placebo patients had to be withdrawn from further participation because of deterioration in their hypertension: in contrast, fifteen of the eighteen frusemide patients showed an anti-hypertensive response and none was withdrawn because of lack of effect. Twice-daily administration of the slow-release formulation, however, produced an unacceptable level of such side-effects as nocturia, nausea and vomiting. Once-daily administration of the preparation is therefore preferred.

Sulphadiazine/Trimethoprim Once Daily in Maxillary Sinusitis: A Randomized Double-Blind Comparison with Sulphamethoxazole/Trimethoprim B.I.D.

1981 ◽  
Vol 9 (6) ◽  
pp. 478-481 ◽  
Author(s):  
Pierre Federspil ◽  
Peter Bamberg
Keyword(s):  
Maxillary Sinusitis ◽  
Favourable Result ◽  
Double Blind Study ◽  
Double Blind ◽  
Once Daily ◽  
Days Of Therapy ◽  
Significant Difference ◽  
Blind Comparison ◽  
Cure Rates

In a randomized double-blind study fifty-four patients suffering from acute maxillary sinusitis were treated for 10 days with daily doses of sulphadiazine/trimethopim (1 g) and sulphamethoxazole/trimethoprim (1.92 g), respectively. The efficacy was evaluated clinically at two follow-up visits. X-ray investigations were performed at admission and after the therapy. Of thirty-nine patients finally evaluated, thirty-seven showed a favourable result. After 6–8 days of therapy there was significant difference in cure rates in favour of sulphadiazine/trimethoprim (p < 0.05) while the outcome as evaluated after treatment was similar for both drugs.

Multicenter, double-blind comparison of doxazosin and atenolol in patients with mild to moderate hypertension

1987 ◽  
Vol 59 (14) ◽  
pp. G73-G77 ◽  
Author(s):  
Peter Ott ◽  
Tommy L. Storm ◽  
Lars R. Krusell ◽  
Herluf Jensen ◽  
Jorgen Badskjaer ◽  
...  
Keyword(s):  
Moderate Hypertension ◽  
Double Blind ◽  
Blind Comparison

scholarly journals Double-blind comparison of captopril and enalapril in mild to moderate hypertension

1986 ◽  
Vol 7 (3) ◽  
pp. 651-660 ◽  
Author(s):  
Peter H. Vlasses ◽  
Dale P. Conner ◽  
Heschi H. Rotmensch ◽  
Richard J. Fruncillo ◽  
Janice R. Danzeisen ◽  
...  
Keyword(s):  
Moderate Hypertension ◽  
Double Blind ◽  
Blind Comparison
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