Action myoclonus induced by visually guided movement

1993 ◽  
Vol 241 (2) ◽  
pp. 92-95 ◽  
Author(s):  
H. Mitoma ◽  
T. Uchihara ◽  
T. Yokota ◽  
T. Furukawa ◽  
H. Tsukagoshi
2006 ◽  
Vol 23 (1-2) ◽  
pp. 19-24
Author(s):  
Rouzbeh Motiei-Langroudi ◽  
Mohsen Omrani ◽  
Mohammad Ali Khoshnoodi ◽  
Firouz Ghaderi Pakdel ◽  
Emad Yazdanpanah ◽  
...  

2015 ◽  
Vol 6 ◽  
Author(s):  
David P. Carey ◽  
E. Grace Otto-de Haart ◽  
Gavin Buckingham ◽  
H. Chris Dijkerman ◽  
Eric L. Hargreaves ◽  
...  

Author(s):  
Anne Beuter ◽  
John G. Milton ◽  
Christiane Labrie ◽  
Deborah Black

AbstractBackground:Here we assess the ability of patients with cerebellar disease to execute a simple visually-guided movement task involving tracking of a target with the index finger.Methods:Spontaneous microdisplacements in index finger position are compared in patients with cerebellar deficits (ischemia [n = 3], multiple sclerosis [n = 3], degenerative cerebellar disease [n = 3]) and age-matched healthy subjects. Subjects were required to maintain a constant finger position relative to a stationary baseline displayed on an oscilloscope.Results:Unusual transient abrupt movements (saccadic or myoclonic-like) directed with or against gravity were seen in patients whose neurological deficits were the most severe (7/9 patients). These abrupt myoclonic-like movements occurred independently of visual input, were not associated with clinically observable myoclonus, and were not detected previously in patients with Parkinson’s disease. These abrupt myoclonic-like movements were not associated with abnormalities in either physiological tremor, or oscillations in finger microdisplacements induced by insertion of a delay (300–1400 ms) into the visual feedback of this finger “holding” experiment. An unexpected finding is that the results obtained for patients with cerebellar deficits by insertion of an experimental delay are not significantly different from those obtained with their age-matched controls.Conclusions:These observations suggest that abrupt myoclonic-like movements are a characteristic abnormality of patients with a variety of cerebellar deficits and emphasize the value of this simple motor tracking task for characterizing movement disorders.


2013 ◽  
Vol 110 (10) ◽  
pp. 2247-2256 ◽  
Author(s):  
J. Kubanek ◽  
C. Wang ◽  
L. H. Snyder

We often look at and sometimes reach for visible targets. Looking at a target is fast and relatively easy. By comparison, reaching for an object is slower and is associated with a larger cost. We hypothesized that, as a result of these differences, abrupt visual onsets may drive the circuits involved in saccade planning more directly and with less intermediate regulation than the circuits involved in reach planning. To test this hypothesis, we recorded discharge activity of neurons in the parietal oculomotor system (area LIP) and in the parietal somatomotor system (area PRR) while monkeys performed a visually guided movement task and a choice task. We found that in the visually guided movement task LIP neurons show a prominent transient response to target onset. PRR neurons also show a transient response, although this response is reduced in amplitude, is delayed, and has a slower rise time compared with LIP. A more striking difference is observed in the choice task. The transient response of PRR neurons is almost completely abolished and replaced with a slow buildup of activity, while the LIP response is merely delayed and reduced in amplitude. Our findings suggest that the oculomotor system is more closely and obligatorily coupled to the visual system, whereas the somatomotor system operates in a more discriminating manner.


2011 ◽  
Vol 301 (1-2) ◽  
pp. 51-58 ◽  
Author(s):  
Darren R. Hocking ◽  
Nicole J. Rinehart ◽  
Jennifer L. McGinley ◽  
Simon A. Moss ◽  
John L. Bradshaw

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