High dose immunoglobulin therapy is effective in the Miller Fisher syndrome

1993 ◽  
Vol 241 (3) ◽  
pp. 178-179 ◽  
Author(s):  
U. Zifko ◽  
M. Drlicek ◽  
G. Senautka ◽  
W. Grisold
Keyword(s):  
Immunoglobulin Therapy ◽  
Miller Fisher Syndrome ◽  
High Dose ◽  
Fisher Syndrome

scholarly journals A Case of Miller-Fisher Syndrome with Syndrome of Inappropriate Secretion of Antidiuretic Hormone

2021 ◽  
pp. 380-383
Author(s):  
Shunya Fujiwara ◽  
Yasuhiro Manabe ◽  
Yumiko Nakano ◽  
Yoshio Omote ◽  
Hisashi Narai ◽  
...  
Keyword(s):  
Antidiuretic Hormone ◽  
Immunoglobulin Therapy ◽  
Sodium Concentration ◽  
Miller Fisher Syndrome ◽  
Intravenous Immunoglobulin Therapy ◽  
Fisher Syndrome ◽  
Upper Respiratory Infection ◽  
Inappropriate Secretion ◽  
Unsteady Gait ◽  
Upper Respiratory

We report a 72-year-old woman with Miller-Fisher syndrome (MFS) with syndrome of inappropriate secretion of antidiuretic hormone (SIADH). She developed diplopia and unsteady gait a week after an upper respiratory infection. Neurologic examination revealed ophthalmoplegia, ataxia, symmetrical weakness, numbness, and areflexia. She underwent intravenous immunoglobulin therapy. Her serum sodium concentration decreased to 119 mEq/L on day 12. She had low plasma osmolarity (254 mosm/kg), high urine osmolarity (457 mosm/kg), and high urine sodium level (73 mEq/L), while the blood level of antidiuretic hormone was normal. Anti-GD1b immunoglobulin G (IgG), -GQ1b IgG, -GT1a IgG, and -Gal-C IgM antibodies were positive. We diagnosed her with MFS overlapping with SIADH. Four weeks after onset, her symptoms recovered. The elevation of anti-GD1b, -GQ1b, and -GT1a antibodies that recognize disialosyl residue may be pathologically related to SIADH.

Intravenous immunoglobulin therapy for Miller Fisher syndrome

Neurology ◽  
2007 ◽  
Vol 68 (14) ◽  
pp. 1144-1146 ◽  
Author(s):  
M. Mori ◽  
S. Kuwabara ◽  
T. Fukutake ◽  
T. Hattori
Keyword(s):  
Intravenous Immunoglobulin ◽  
Immunoglobulin Therapy ◽  
Miller Fisher Syndrome ◽  
Intravenous Immunoglobulin Therapy ◽  
Fisher Syndrome
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