Protective action of some diphosphonates against injury to lymphocytes by antilymphocytic serum

1978 ◽  
Vol 86 (3) ◽  
pp. 1215-1217
Author(s):  
I. N. Zernov ◽  
D. V. Stefani ◽  
Yu. E. Vel'tishchev
Keyword(s):  
Protective Action ◽  
Antilymphocytic Serum

Liquorice exaggerates protective action of Solanum xanthocarpum against cigarette smoke induced pulmonary inflammation

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
RA Manek ◽  
NR Sheth ◽  
JR Chavda ◽  
JD Vaghasiya ◽  
KP Modi ◽  
...  
Keyword(s):  
Cigarette Smoke ◽  
Protective Action ◽  
Pulmonary Inflammation ◽  
Solanum Xanthocarpum

Action of Lysolecithin on Blood Platelets

1963 ◽  
Vol 09 (03) ◽  
pp. 512-524 ◽  
Author(s):  
Chava Kirschmann ◽  
Sara Aloof ◽  
Andre de Vries
Keyword(s):  
Blood Platelets ◽  
Protective Action ◽  
Platelet Surface ◽  
Washed Platelet ◽  
Sufficient Concentration ◽  
Saline Medium

SummaryLysolecithin is adsorbed to washed blood platelets and, at sufficient concentration, lyses them, inhibits their clot-retracting activity and promotes their thromboplastin-generating activity. Lysolecithin adsorption to the platelet was studied by using P32-labelled lysolecithin obtained from the liver of rats injected with labelled orthophosphate. The amount of lysolecithin adsorbed to the surface of the washed platelet in saline medium is dependent on the concentration of lysolecithin in solution and reaches saturation — 5 × 10-8 jig per platelet — at a concentration of 9—10 µg per ml. Platelet lysis in saline medium begins at a lysolecithin concentration higher than 18 jig per ml. Plasma and albumin prevent adsorption of lysolecithin to the platelet and protect the platelet from damage by lysolecithin. Albumin is able to remove previously adsorbed lysolecithin from the platelet surface. The protective action of plasma explains the lack of platelet damage in blood, the plasma lecithin of which has been converted to lysolecithin by the action of Vipera palestinae venom phosphatidase, in vitro and in vivo.

Natural Anti-inflammatory compounds as Drug candidates in Alzheimer’s disease

2020 ◽  
Vol 27 ◽  
Author(s):  
Reyaz Hassan Mir ◽  
Abdul Jalil Shah ◽  
Roohi Mohi-ud-din ◽  
Faheem Hyder Potoo ◽  
Mohd. Akbar Dar ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Natural Products ◽  
Protective Action ◽  
New Drugs ◽  
Huperzine A ◽  
Brain Disorder ◽  
Anti Inflammatory

: Alzheimer's disease (AD) is a chronic neurodegenerative brain disorder characterized by memory impairment, dementia, oxidative stress in elderly people. Currently, only a few drugs are available in the market with various adverse effects. So to develop new drugs with protective action against the disease, research is turning to the identification of plant products as a remedy. Natural compounds with anti-inflammatory activity could be good candidates for developing effective therapeutic strategies. Phytochemicals including Curcumin, Resveratrol, Quercetin, Huperzine-A, Rosmarinic acid, genistein, obovatol, and Oxyresvertarol were reported molecules for the treatment of AD. Several alkaloids such as galantamine, oridonin, glaucocalyxin B, tetrandrine, berberine, anatabine have been shown anti-inflammatory effects in AD models in vitro as well as in-vivo. In conclusion, natural products from plants represent interesting candidates for the treatment of AD. This review highlights the potential of specific compounds from natural products along with their synthetic derivatives to counteract AD in the CNS.

Protective Action of Bile Acids in Experimental Thyrotoxicosis

1961 ◽  
Vol 75 (3) ◽  
pp. 347-353
Author(s):  
L. R. Overby ◽  
R. L. Fredrickson
Keyword(s):  
Bile Acids ◽  
Protective Action ◽  
Experimental Thyrotoxicosis

The Protective Action of the Aqueous Extract of Auricularia polytricha in Paracetamol Induced Hepatotoxicity in Rats

2016 ◽  
Vol 10 (1) ◽  
pp. 72-76 ◽  
Author(s):  
Dinesh K. Chellappan ◽  
Sivamalar Ganasen ◽  
Shaminiswary Batumalai ◽  
Mayuren Candasamy ◽  
Purushotham Krishnappa ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Protective Action ◽  
Auricularia Polytricha
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