Investigation of humoral immunity in mice with transplantable leukemia during immunochemotherapy

1975 ◽  
Vol 80 (6) ◽  
pp. 1481-1483
Author(s):  
G. M. Sukhin ◽  
B. N. Kovalev ◽  
T. A. Sinel'shchikova ◽  
V. M. Bergol'ts
Keyword(s):  
Humoral Immunity ◽  
Transplantable Leukemia

Author response for "Human pregnancy levels of estrogen and progesterone contribute to humoral immunity by activating T FH /B cell axis"

2020 ◽  
Author(s):  
Clarice Monteiro ◽  
Taissa Kasahara ◽  
Priscila M. Sacramento ◽  
Aleida Dias ◽  
Simone Leite ◽  
...  
Keyword(s):  
B Cell ◽  
Humoral Immunity ◽  
Author Response ◽  
Cell Axis ◽  
Human Pregnancy

Assessment of cellular immunity in oil production operators with an imbalance of lipid metabolism

2020 ◽  
Vol 60 (11) ◽  
pp. 717-719
Author(s):  
Inga N. Alikina ◽  
Olga A. Kazakova
Keyword(s):  
Lipid Metabolism ◽  
Humoral Immunity ◽  
Cellular Immunity ◽  
Comparison Group ◽  
Oil Production ◽  
Observation Group ◽  
Immunological Parameters ◽  
Production Factors ◽  
Cellular And Humoral Immunity ◽  
Atherosclerotic Process

Introduction. Studies indicate the high pathogenetic significance of the immune component in the development of atherosclerosis. The aim of the study is a comparative assessment of immunological parameters in workers of petrochemical production with varying degrees of imbalance in lipid metabolism and the development of the atherosclerotic process. Materials and methods. Men working at an oil production enterprise in the Perm Region were examined. The observation group consisted of oil production operators with a diagnosis of atherosclerosis, the comparison group - with dyslipidemia syndrome. To determine the parameters of lipid metabolism, the results of a biochemical blood test were used. CD-immunogram parameters were identified by flow cytometry. Specific antibodies to benzene were determined by the allergosorbent method. Results. The results of a comparative study of fat metabolism confirmed violations of the physiological ratio of lipids in the blood of oil production workers, which were expressed in a significant imbalance in the levels of lipidogram. There was an increased level of specific IgG antibodies to benzene in the observation group in relation to the comparison group. An imbalance of cellular immunity was found, which was characterized by signs of indicators activation of cellular differentiation clusters. Conclusions. Studies of immune system compartments demonstrate excessive activation of cellular and humoral immunity in oil production workers under the influence of a combination of harmful production factors. The simultaneously formed imbalance of lipid metabolism is associated with various degrees of clinical manifestation of atherosclerotic disorders, with the influence of harmful production factors, aggressiveness of cellular and humoral immunity, and smoking.

Factors of humoral immunity in the combined course of vibration disease and hypertension

2020 ◽  
pp. 558-559
Author(s):  
R. A. Baraeva ◽  
L. A. Strizhakov ◽  
Y. I. Borzykh
Keyword(s):  
Humoral Immunity ◽  
Clinical Picture ◽  
Pathogenetic Mechanisms ◽  
Vibration Disease ◽  
Mechanisms Of Formation

The study of humoral immunity factors in vibration disease and its combination with hypertension opens up prospects for rehabilitation and treatment of patients with this pathology, as well as complements our knowledge of the pathogenetic mechanisms of formation of the clinical picture of these diseases.

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