Seasonal changes in blood pressure and some parameters of cardiac contractility in intact rabbits

1991 ◽  
Vol 112 (4) ◽  
pp. 1505-1507
Author(s):  
V. A. Frolov ◽  
�. S. Matyev ◽  
T. A. Kazanskaya ◽  
V. A. Mogilevskii ◽  
V. K. Lepakhin
Keyword(s):  
Blood Pressure ◽  
Seasonal Changes ◽  
Cardiac Contractility

scholarly journals Seasonal Changes in Preprandial Glucose, A1C, and Blood Pressure in Diabetic Patients: Response to Liang

Diabetes Care ◽  
2007 ◽  
Vol 30 (11) ◽  
pp. e118-e118 ◽  
Author(s):  
M. C. Honeyman ◽  
S. Elkassaby ◽  
L. C. Harrison
Keyword(s):  
Blood Pressure ◽  
Seasonal Changes ◽  
Diabetic Patients

Inotropes and Vasopressors for Shock

2019 ◽  
Author(s):  
Amour B U Patel ◽  
Gareth L Ackland
Keyword(s):  
Blood Pressure ◽  
Animal Studies ◽  
Cardiac Contractility ◽  
Clinical Trial Data ◽  
Cardiovascular Effects ◽  
Evidence Base ◽  
End Points ◽  
Arterial Blood ◽  
End Stage ◽  
The Impact

Inotropes and vasopressors play a key role in the management of shock. The goal of therapy is to restore end-organ perfusion by augmenting cardiac output (CO) and vascular tone. Clinical trial data have thus far failed to identify precise hemodynamic end points associated with better outcomes; in any event, such end points are highly likely to be determined on an individualized basis, reflecting patients’ chronic arterial blood pressure, baseline cardiac function, and other pathophysiologic factors (e.g., end-stage renal failure, cardiac ischemia).1 Inotropes enhance cardiac contractility and CO; vasopressors raise blood pressure. The impact of these drugs in restoring hemodynamic parameters to “normal” values has principally been used to evaluate their effectiveness, with clinical practice guided by extrapolation from animal studies and pharmacologic trials.2 However, these drugs have important extra-cardiovascular effects on metabolic, neurohormonal, and autonomic regulation that are also injurious. This review discusses the mechanisms and evidence base for inotropes and vasopressors in various types of shock. This review contains 3 figures, and 39 references. Keywords: inotropes, vasopressors, catecholamines, monitoring, shock states, cardiogenic, hemorrhagic, septic, neurogenic

scholarly journals Response to Seasonal Changes in Blood Pressure: Possible Interaction Between Sunlight and Brain Serotonin

Hypertension ◽  
2013 ◽  
Vol 62 (1) ◽  
Author(s):  
Pietro Amedeo Modesti ◽  
Stefano Rapi ◽  
Gian Franco Gensini ◽  
Marco Morabito ◽  
Simone Orlandini ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Seasonal Changes ◽  
Brain Serotonin

Seasonal Changes in Blood Pressure and Frequency of Related Complications in Elderly Israeli Patients with Essential Hypertension

Gerontology ◽  
2004 ◽  
Vol 50 (5) ◽  
pp. 315-321 ◽  
Author(s):  
Gideon Charach ◽  
Pavel D. Rabinovich ◽  
Moshe Weintraub
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Seasonal Changes

Increased cardiac contractility in acute uremia: interrelationships with hypertension

1975 ◽  
Vol 229 (2) ◽  
pp. 501-505 ◽  
Author(s):  
T Nivatpumin ◽  
T Yipintsoi ◽  
S Penpargkul ◽  
J Scheuer
Keyword(s):  
Blood Pressure ◽  
Systolic Hypertension ◽  
Diastolic Pressure ◽  
Cardiac Contractility ◽  
Systolic Pressure ◽  
Pressure Rise ◽  
Left Ventricular ◽  
Ventricular Systolic Pressure ◽  
Inotropic State ◽  
Left Ventricular Systolic Pressure

To study the effects of acute uremia on the inotropic state of the rat heart, we subjected rats to bilateral nephrectomy and studied their hearts in the open chest 24 h later. Uremic rats had significantly higher systolic blood pressure than sham-operated animals. Left ventricular systolic pressure and maximum dP/dt, both during ejection and isovolumic contrations, were higher for any given end-diastolic pressure in hearts of uremic rats than in sham-operated animals. This difference in performance charcteristics was not abolished by doses of propranolol that blocked the heart rate response to isoproterenol. The administration of phenoxybenzamine during the 24 h of uremia abolished the blood pressure rise in uremic rats, but the increased contractile state persisted. Treatment of sham-operated animals with methoxamine to produce the same course of blood pressure as observed in uremic rats was also associated with an increased inotropic state. These results indicate that in the rat, acute uremia is associated with an increased inotropic state that is not mediated by beta-adrenergic mechanisms. The systolic hypertension of acute uremia is not the major cause of the increased contractility, although systolic hypertension without uremia can mimic the performance characteristics found in hearts of uremic rats.

ON THE HYPERTENSIVE ACTION OF TOLAZOLINE AND HYDERGINE

1963 ◽  
Vol 41 (1) ◽  
pp. 941-946 ◽  
Author(s):  
B. G. Benfey ◽  
D. R. Varma
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiac Contractility ◽  
Pressure Rise ◽  
Pressor Effect ◽  
Blood Pressure Rise ◽  
Chronotropic Effects

The effects of tolazoline and Hydergine on blood pressure, cardiac contractility, and heart rate have been studied in dogs under pentobarbitone anesthesia. Whereas in the absence of reserpine, tolazoline had a pressor effect in two of four dogs, following reserpine it had a marked pressor action in each of eight dogs. The blood pressure rise was associated with positive inotropic and negative chronotropic effects. Phenoxybenzamine abolished these effects of tolazoline. Hydergine had pressor and negative chronotropic effects in the absence of reserpine. Following reserpine these effects were associated with positive inotropic actions. Phenoxybenzamine reduced these effects of Hydergine. It is concluded that the pressor action of tolazoline is wholly due to adrenergic vasoconstriction, whereas that of Hydergine is only partly an adrenergic effect.

scholarly journals Effects of Concentrated Ambient Particles on Heart Rate, Blood Pressure, and Cardiac Contractility in Spontaneously Hypertensive Rats

2004 ◽  
Vol 16 (6-7) ◽  
pp. 421-429 ◽  
Author(s):  
Chuen-Chau Chang ◽  
Jing-Shiang Hwang ◽  
Chang-Chuan Chan ◽  
Peng-Yau Wang ◽  
Tsuey-Hwa Hu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Spontaneously Hypertensive Rats ◽  
Cardiac Contractility ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Ambient Particles

Inverse Correlation Between Seasonal Changes in Home Blood Pressure and Atmospheric Temperature in Treated-Hypertensive Patients

2010 ◽  
Vol 32 (4) ◽  
pp. 221-226 ◽  
Author(s):  
Akihiro Iwabu ◽  
Kumi Konishi ◽  
Hiroe Tokutake ◽  
Shinichi Yamane ◽  
Hiromichi Ohnishi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Seasonal Changes ◽  
Inverse Correlation ◽  
Atmospheric Temperature ◽  
Home Blood Pressure ◽  
Hypertensive Patients

Seasonal changes in blood pressure in chronic kidney disease patients

2010 ◽  
Vol 73 (03) ◽  
pp. 216-220 ◽  
Author(s):  
S.-H. Bi ◽  
L.-T. Cheng ◽  
D.-X. Zheng ◽  
T. Wang
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Seasonal Changes
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