Effect of stimulation and inhibition of lipid peroxidation on kinetics of myoglobin and creatine kinase in uncomplicated and complicated healing of experimental myocardial infarction

1991 ◽  
Vol 111 (5) ◽  
pp. 631-634
Author(s):  
V. N. Sokrut ◽  
N. I. Yabluchanskii ◽  
L. A. Pavlenko ◽  
T. V. Makhalova
Keyword(s):  
Myocardial Infarction ◽  
Lipid Peroxidation ◽  
Creatine Kinase ◽  
Experimental Myocardial Infarction ◽  
Kinetics Of

Lipid peroxidation in experimental myocardial infarction: Action of hyperbaric oxygenation

1984 ◽  
Vol 98 (4) ◽  
pp. 1316-1318
Author(s):  
F. Z. Meerson ◽  
V. V. Didenko ◽  
V. M. Savov ◽  
R. A. Kopaladze ◽  
R. S. Dosmagambetova ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Lipid Peroxidation ◽  
Hyperbaric Oxygenation ◽  
Experimental Myocardial Infarction

Evaluation of Serum Creatine Kinase and Lactate Dehydrogenase in Experimental Myocardial Infarction, Atriotomies, and Thoracotomies

1986 ◽  
Vol 41 (4) ◽  
pp. 378-386 ◽  
Author(s):  
Robert E. Wolf ◽  
Geoffrey M. Graeber ◽  
J. Robert Burge ◽  
James L. DeShong ◽  
John L. MacDonald ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Experimental Myocardial Infarction ◽  
Serum Creatine Kinase

Isoforms of creatine kinase isoenzymes in serum in acute myocardial infarction after intracoronary thrombolysis.

1987 ◽  
Vol 33 (11) ◽  
pp. 2039-2042 ◽  
Author(s):  
M Panteghini ◽  
F Pagani
Keyword(s):  
Myocardial Infarction ◽  
Creatine Kinase ◽  
Therapy Group ◽  
Time Lag ◽  
Maximum Activity ◽  
Group A ◽  
Conventional Therapy Group ◽  
Group B ◽  
To Receive ◽  
Kinetics Of

Abstract Kinetics of the catalytic activities of creatine kinase (CK;EC 2.7.3.2) for three CK-3 and two CK-2 isoforms in serum were studied in 20 patients with myocardial infarction randomly assigned to receive either intracoronary urokinase (group A) or conventional therapy (group B). The temporal characteristics of isoform changes described were (a) time at which the isoform activities are significantly greater than initial values, (b) maximal rate (Ka) at which isoforms are released into blood, (c) time lag from onset of pain until maximum activity value, (d) peak value of each serum isoform, and (e) rate (Kd) at which each isoform is cleared from serum. Thrombolytic treatment induced earlier peak times in group A: for CK-3(3), 7.4 vs 20.0 h; for CK-3(2), 11.6 vs 24.8; for CK-3(1), 18.6 vs 34.3; for CK-2(2), 9.1 vs 17.8; and for CK-2(1), 11.8 vs 26.8 (numbers given are medians; for all isoforms, P less than 0.05). Ka values were at least twofold greater and the first increase was significantly earlier in the urokinase group. Consequently, the ratio for CK-3(3) to CK-3(1) activities peaked significantly earlier in group A. Isoform peak activities and Kd were not significantly different between the two groups.

Sign in / Sign up

Export Citation Format

Share Document