Effect of low-intensity infrared laser radiation on ultrastructure and proliferation of liver cells in experimental hepatitis and cirrhosis

1992 ◽  
Vol 113 (4) ◽  
pp. 571-574
Author(s):  
I. M. Baibekov ◽  
V. M. Vorozheikin ◽  
Sh. N. Artykov
Author(s):  
L. V. Brun ◽  
V. I. Makolinets

The aim of this study is to determine the influence of low-intensity infrared laser radiation (LIIRLR) on concentrationof diclofenac sodium in the experiment on rats by the method of high-performance liquid chromatography. For study conduct, a total of 15 male rats with body weight of 250–300 g were used. Experimental animals were subdivided into 3 groups. Animals of group 1 received diclofenac sodium per os at the dose of ED50 (8 mg/kg of animal body weight). Animals of group 2 received diclofenac sodium per os (8 mg/kg) and in 15 min were exposed to LIIRLR. Animals of group 3 were exposed to LIIRLR and in 15 min received diclofenac sodium per os at the dose of 8 mg/kg. Animals were sacrificed in 60 min after drug administration. For extraction of diclofenac sodium from rat plasma samples, we used a method of solid-phase extraction, which had been modified due to microoncentrationsof the active substance. In the result of the studies conducted, it has been determined that therapy regimen with the following sequence is the most efficient in the animals studied: exposure of LIIRLR and administration per os of diclofenac sodium in15 min. The results obtained indicate to the fact that concomitant use of LIIRLR potentiates diclofenac sodium. Itwill allow to decrease the dose, influence on its entry and duration of its action in the organism, as well as to decreasethe frequency of drug administration.


2018 ◽  
Vol 1 (2) ◽  
pp. 10-19
Author(s):  
Yu. М. Iryanov ◽  
N. A. Kiryanov

Introduction: The use of non-medicinal facilities for correcting processes in various pathological conditions is one of the most urgent problems of modern medicine. Purpose of the Work: To study the effect of low-intensity infrared laser radiation on reparative bone formation and angiogenesis in bone regeneration which is formed in treatment of fractures under conditions of transosseous osteosynthesis. Material and Methods: A tibia fracture was modeled experimentally in rats in the control and experimental groups. Reposition and fixation of fragments were performed. The fracture zone in the experimental group animals was exposed to the impact of pulsed infrared laser irradiation of low intensity. Animals from the control group underwent the impact simulation. The operated bones were investigated using the methods of X-ray, light and electron microscopy, X-ray electron probe microanalysis. Results: It was established that laser radiation exposure sessions activated fibrillogenesis and angiogenesis, accelerated compacting of newly formed bone tissue and increased its maturity while primary fracture healing occurred. Prolonged capillary dilatation and endothelium-dependent vasodilation, intensive capillarogenesis were noted after sessions of laser therapy in bone regeneration. Endothelial outgrowth was formed in the lumen of the vessels forming capillary buds that propagate along the “mother” vessels (endovascular capillarogenesis). Conclusion: The data obtained revealed a possible mechanism of laser radiation exposure at the level of a whole organism and proved the effectiveness of its application in clinical practice at the early stages of patient rehabilitation under conditions of transosseous osteosynthesis.


Author(s):  
S. V. Razaev ◽  
G. N. Vyayzenen ◽  
N. V. Popova ◽  
A. G. Vyayzenen ◽  
K. A. Ambartsumova ◽  
...  

The growth of production and consumption of dietary poultry meat causes an urgent need to develop and use new and more effective elements of technologically complete compound feed and broiler chicken rearing in the regions. In order to increase the range of non-traditional feed products and feed additives and reduce the deficit of raw protein, amino acids and vitamins, it is advisable to use non-traditional methods to increase the efficiency of compound feed use when broilers rearing. One of the available non-traditional methods for increasing the efficiency of using compound feed in meat production should be considered the use of synthetic amino acids for a new purpose, namely as a modulator of spatial through the infrared laser beam. The purpose of the research was to improve the industrial technology for rearing of broiler chickens using aeroionotherapy and low-intensity laser radiation. Experimental studies have been carried out under the production conditions of poultry house No. 1 (halls No. 2 and No. 3) of the Novgorodskaya poultry farm in the Novgorod region. Broiler chickens of cross Ross 508 have been kept in three-tier BKM-3B cell batteries. The use of low-intensity infrared laser radiation with minimal parameters of the “Uzor 2K-Super” laser (80 Hz wavelength) and air ionization of air oxygen (AN-1 and AI-P aeronizers, modes 2 and 3) against the background of the main diet of cross-Ross 508 broiler chickens improved the state of carbohydrate, protein, fat, amino acid, and vitamin metabolism by increasing the assimilation processes of their body. It has been caused functional activation of the digestive system in it, along with an increase in enzyme, immune and hormonal systems and made it possible to fully realize the level of meat productivity, feed-efficiency and improve some blood biochemical parameters.


The Eye ◽  
2019 ◽  
Vol 127 (2019-3) ◽  
pp. 7-11
Author(s):  
Fazilat Bakhritdinova

Purpose: A cytological assessment of the effectiveness of eye burns complex treatment using low-intensity infrared laser radiation (LILR) was performed. Material and methods. 42 patients (64 eyes) with eye burns of different etiology and severity were examined. For the patients of the main group (21 patients, 30 eyes) low-intensity infrared laser radiation was added to the traditional treatment methods. Results. Decrease in the number of basophils and the amount of exudation during the inflammatory process indicated the suppression of the initial forms of inflammatory mediators – histamine and serotonin; the disappearance of leukocytes and restoration of the cytoplasm structure and epithelial nuclei was the result of the prostaglandins and leukotrienes suppression by LILR. An increase in the nuclear cytoplasmic ratio (NCR) was the result of the metabolic processes activation and the increase of their regenerative ability. Conclusion. Therefore, the use of LIRL is considered to be an effective method of the eye burn treatment since it triggers and prolongs the effect of the primary therapy.


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