Character of formation of a generator of pathologically enhanced excitation (epileptic focus) in the rat sensomotor cortex during repetitive electrical stimulation

1991 ◽  
Vol 112 (3) ◽  
pp. 1224-1228
Author(s):  
G. N. Kryzhanovskii ◽  
V. K. Lutsenko ◽  
N. N. Khlebnikova ◽  
M. Yu. Karganov
Keyword(s):  
Electrical Stimulation ◽  
Sensomotor Cortex ◽  
Epileptic Focus ◽  
Repetitive Electrical Stimulation

scholarly journals Excitability of the motoneuron after repetitive electrical stimulation to the tibial nerve.

1990 ◽  
Vol 5 (2) ◽  
pp. 77-80
Author(s):  
Hirobumi KAWAMURA ◽  
Takamasa TSURUMI ◽  
Morihiro TSUJISHITA ◽  
Hiroshi YAMAMOTO ◽  
Tetsuro SADAHIRO ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Tibial Nerve ◽  
Repetitive Electrical Stimulation

Polarity of effects of stimulation of Auerbach's plexus on longitudinal muscle.

1978 ◽  
Vol 235 (4) ◽  
pp. E345
Author(s):  
S Yokoyama ◽  
T Ozaki
Keyword(s):  
Electrical Stimulation ◽  
Longitudinal Muscle ◽  
Oral Side ◽  
Metal Microelectrode ◽  
Rabbit Intestine ◽  
Auerbach’S Plexus ◽  
Repetitive Electrical Stimulation ◽  
Auerbach's Plexus ◽  
Anal Side ◽  
Stimulation Of

The effects of repetitive electrical stimulation of nodes in Auerbach's plexus on the longitudinal muscle of rabbit intestine were investigated. Peeled longitudinal muscle strips, with adherent Auerbach's plexus, were obtained and placed under a stereodissecting microscope. Neural elements within nodes of Auerbach's plexus were stimulated repetitively using a metal microelectrode with tip diameter of 5 micrometer. Stimuli applied to a node generally caused excitation of the longitudinal muscle on the oral side and inhibition on the anal side of the point of stimulation. Excitation of the muscle was mainly cholinergic, and inhibition of the muscle was nonadrenergic. From the results of the present study the concept of the law of the intestine, excitation above and inhibition below the stimulated spot, was supported.

scholarly journals Characterization of silent afferents in the pelvic and splanchnic innervations of the mouse colorectum

2011 ◽  
Vol 300 (1) ◽  
pp. G170-G180 ◽  
Author(s):  
Bin Feng ◽  
G. F. Gebhart
Keyword(s):  
Irritable Bowel Syndrome ◽  
Electrical Stimulation ◽  
Krebs Solution ◽  
Inflammatory Soup ◽  
Repetitive Electrical Stimulation ◽  
Irritable Bowel ◽  
Activity Dependent ◽  
Circumferential Stretch

Hypersensitivity in inflammatory/irritable bowel syndrome is contributed to in part by changes in the receptive properties of colorectal afferent endings, likely including mechanically insensitive afferents (MIAs; silent afferents) that have the ability to acquire mechanosensitivity. The proportion and attributes of colorectal MIAs, however, have not previously been characterized. The distal ∼3 cm of colorectum with either pelvic (PN) or lumbar splanchnic (LSN) nerve attached was removed, opened longitudinally, pinned flat in a recording chamber, and perfused with oxygenated Krebs solution. Colorectal receptive endings were located by electrical stimulation and characterized as mechanosensitive or not by blunt probing, mucosal stroking, and circumferential stretch. MIA endings were tested for response to and acquisition of mechanosensitivity by localized exposure to an inflammatory soup (IS). Colorectal afferents were also tested with twin-pulse and repetitive electrical stimulation paradigms. PN MIAs represented 23% of 211 afferents studied, 71% (30/42) of which acquired mechanosensitivity after application of IS to their receptive ending. LSN MIAs represented 33% of 156 afferents studied, only 23% (11/48) of which acquired mechanosensitivity after IS exposure. Mechanosensitive PN endings uniformly exhibited significant twin-pulse slowing whereas LSN endings showed no significant twin-pulse difference. PN MIAs displayed significantly greater activity-dependent slowing than LSN MIAs. In conclusion, significant proportions of MIAs are present in the colorectal innervation; significantly more in the PN than LSN acquire mechanosensitivity in an inflammatory environment. This knowledge contributes to our understanding of the possible roles of MIAs in colon-related disorders like inflammatory/irritable bowel syndrome.

Increase in glutamate receptors following repetitive electrical stimulation in hippocampal slices

Life Sciences ◽  
1980 ◽  
Vol 27 (4) ◽  
pp. 325-330 ◽  
Author(s):  
M. Baudry ◽  
M. Oliver ◽  
R. Creager ◽  
A. Wieraszko ◽  
G. Lynch
Keyword(s):  
Electrical Stimulation ◽  
Glutamate Receptors ◽  
Hippocampal Slices ◽  
Repetitive Electrical Stimulation

Increased synthesis of two polypeptides in area CA1 of the hippocampus in response to repetitive electrical stimulation

1991 ◽  
Vol 567 (2) ◽  
pp. 248-252 ◽  
Author(s):  
Noriaki Uenishi ◽  
Tracey J. Shors ◽  
Caleb E. Finch ◽  
Nancy R. Nichols ◽  
Richard F. Thompson
Keyword(s):  
Electrical Stimulation ◽  
Area Ca1 ◽  
Repetitive Electrical Stimulation

Contraction-induced excitation in cat peroneal motoneurons

1995 ◽  
Vol 73 (3) ◽  
pp. 974-982 ◽  
Author(s):  
N. Kouchtir ◽  
J. F. Perrier ◽  
D. Zytnicki ◽  
L. Jami
Keyword(s):  
Electrical Stimulation ◽  
Distal Portion ◽  
Afferent Input ◽  
Ventral Root ◽  
Triceps Surae ◽  
Group I ◽  
Peroneus Brevis ◽  
Repetitive Electrical Stimulation ◽  
Tendon Organ ◽  
Stimulation Of

1. Motoneurons innervating peroneal muscles were recorded intracellularly in anesthetized cats during sustained submaximal isometric contractions of peroneus brevis produced by repetitive electrical stimulation of motor axons in the distal portion of cut ventral root filaments. 2. In contrast with the inhibition previously observed during contractions of gastrocnemius medialis muscle in triceps surae motoneurons, the afferent input generated by peroneus brevis contraction elicited excitatory potentials in nearly all motoneurons supplying peroneus brevis, peroneus tertius, or peroneus longus muscles. 3. We ascribed the contraction-induced excitation of peroneal motoneurons to spindle afferents for two reasons. First, the amplitude of contraction-induced excitatory potentials increased when the ventral root stimulation strength was increased to recruit gamma-axons. Second, with stimulation strengths under gamma-threshold, peroneus brevis contraction still excited peroneal motoneurons, and we obtained evidence that activation of spindles by skeletofusimotor beta-axons could account at least partly for this excitation. 4. The lack of contraction-induced inhibition in peroneal motoneurons and the prevalence of contraction-induced excitation raised the possibility that, in contrast to the usual effects of tendon organ afferents, Ib afferents from peroneus brevis might exert an excitatory influence on homonymous motoneurons. The fact that electrical stimulation of group I afferents in the nerve to peroneus brevis only exceptionally evoked inhibition in peroneal motoneurons would appear compatible with this hypothesis. Furthermore, stimulation of cutaneous afferents, known to facilitate transmission in Ib pathways, only exceptionally revealed a weak contraction-induced inhibition.(ABSTRACT TRUNCATED AT 250 WORDS)

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