Zonal corticosteroid hormone biosynthesis in the adrenal cortex in rats exposed to emotional stress combined with salt loading

1987 ◽  
Vol 103 (2) ◽  
pp. 169-172
Author(s):  
V. A. Shul'ga
Keyword(s):  
Adrenal Cortex ◽  
Emotional Stress ◽  
Salt Loading ◽  
Hormone Biosynthesis ◽  
Corticosteroid Hormone

scholarly journals Development of a Prototype Lateral Flow Immunoassay of Cortisol in Saliva for Daily Monitoring of Stress

Biosensors ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 146
Author(s):  
Elizaveta Panfilova
Keyword(s):  
Healthy Volunteers ◽  
Adrenal Cortex ◽  
Emotional Stress ◽  
Salivary Cortisol ◽  
Daily Life ◽  
Lateral Flow ◽  
Point Of View ◽  
Lateral Flow Immunoassay ◽  
Daily Monitoring

Emotional stress negatively affects the quality of a person’s daily life. From a physiological point of view, stress is expressed in the excitation of the hypothalamic–pituitary–adrenal cortex axis, which leads to the release of the hormone cortisol into the blood. We developed a lateral flow immunoassay to detect cortisol in human salivary fluid and tested it on 10 healthy volunteers daily for about one month n = 293 saliva samples). Cortisol was detected in concentrations ranging from 1 to 70 ng/mL. Salivary cortisol levels were confirmed by ELISA. The straightness range of LFIA calibration was from 1 to 100 ng/mL. The diagnostic sensitivity of the method was 73%. It was found that in 3 out of 10 subjects, fluctuations in the level of cortisol in saliva partially corresponded to the subjectively assessed level of stress.

Reaction of the Adrenal Cortex to Emotional Stress

1956 ◽  
Vol 18 (1) ◽  
pp. 56-76 ◽  
Author(s):  
EUGENE L. BLISS ◽  
CLAUDE J. MIGEON ◽  
HARDIN C. H. BRANCH ◽  
LEO T. SAMUELS
Keyword(s):  
Adrenal Cortex ◽  
Emotional Stress

Reaction of the Adrenal Cortex to Physical and Emotional Stress in College Oarsmen

1951 ◽  
Vol 244 (20) ◽  
pp. 754-757 ◽  
Author(s):  
Albert E. Renold ◽  
T. B. Quigley ◽  
Harrison E. Kennard ◽  
George W. Thorn
Keyword(s):  
Adrenal Cortex ◽  
Emotional Stress

scholarly journals 60 YEARS OF POMC: N-terminal POMC peptides and adrenal growth

2016 ◽  
Vol 56 (4) ◽  
pp. T39-T48 ◽  
Author(s):  
Andrew B Bicknell
Keyword(s):  
Adrenal Cortex ◽  
Short Review ◽  
Peptide Hormones ◽  
Adrenal Function ◽  
Personal Perspective ◽  
Basic Principles ◽  
Hormone Biosynthesis ◽  
Key Questions

The peptide hormones contained within the sequence of proopiomelanocortin (POMC) have diverse roles ranging from pigmentation to regulation of adrenal function to control of our appetite. It is generally acknowledged to be the archetypal hormone precursor, and as its biology has been unravelled, so too have many of the basic principles of hormone biosynthesis and processing. This short review focuses on one group of its peptide products, namely, those derived from the N-terminal of POMC and their role in the regulation of adrenal growth. From a historical and a personal perspective, it describes how their role in regulating proliferation of the adrenal cortex was identified and also highlights the key questions that remain to be answered.

Ultrastructural Cytopiasmic Changes of Adrenal Cortex During Pregnancy

1969 ◽  
Vol 27 ◽  
pp. 298-299
Author(s):  
T. M. Murad ◽  
Karen Israel ◽  
Jack C. Geer
Keyword(s):  
Adrenal Gland ◽  
Steroid Hormones ◽  
Adrenal Cortex ◽  
Lipid Droplets ◽  
Plasma Cholesterol ◽  
Adrenal Steroids ◽  
Dynamic Changes ◽  
Cortical Cells ◽  
Acetyl Coenzyme A ◽  
Adrenal Cortical Cells

Adrenal steroids are normally synthesized from acetyl coenzyme A via cholesterol. Cholesterol is also shown to enter the adrenal gland and to be localized in the lipid droplets of the adrenal cortical cells. Both pregnenolone and progesterone act as intermediates in the conversion of cholesterol into steroid hormones. During pregnancy an increased level of plasma cholesterol is known to be associated with an increase of the adrenal corticoid and progesterone. The present study is designed to demonstrate whether the adrenal cortical cells show any dynamic changes during pregnancy.

Adrenocortical Ultrastructure in Ectopic Acth Syndrome

1976 ◽  
Vol 34 ◽  
pp. 238-239
Author(s):  
K. Kovacs ◽  
E. Horvath ◽  
W. Singer
Keyword(s):  
Adrenal Cortex ◽  
Zona Glomerulosa ◽  
Ectopic Acth Syndrome ◽  
Pituitary Neoplasms ◽  
Electron Microscopic ◽  
Adrenocortical Cells ◽  
Cell Hyperplasia ◽  
Ectopic Acth ◽  
Ectopic Acth Production ◽  
Microscopic Findings

Secretion of ACTH by non-pituitary neoplasms is recognized with increasing frequency. While the clinical and biochemical changes associated with ectopic ACTH production have been extensively studied recently, relatively little attention was focused on the morphology of the adrenal cortex and, to our knowledge, the fine structure of the adrenocortical cells in cases of ectopic ACTH syndrome has not been described so far. We report here the electron microscopic findings in the adrenal cortex of a 50-year-old man with a pancreatic apudoma. The patient showed the characteristic clinical and biochemical features of ectopic ACTH syndrome and because of extensive hypercorticism, underwent bilateral adrenalectomy.By light microscopy, the adrenal cortices showed extensive compact cell hyperplasia and lipid depletion. The zona glomerulosa was present in small foci and, except for a few places, fasciculata cells were noted under the fibrous capsule.

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