In vivo production of macrophage migration inhibition and stimulation factors during the inductive phase of the alloimmune response

1986 ◽  
Vol 102 (1) ◽  
pp. 949-952 ◽  
Author(s):  
A. P. Suslov ◽  
A. K. Yazova ◽  
N. P. Berkova
1970 ◽  
Vol 131 (3) ◽  
pp. 603-610 ◽  
Author(s):  
Yves Borel ◽  
John R. David

Suppression of delayed hypersensitivity in vivo is correlated in vitro with the absence of macrophage migration inhibition in the presence of the antigen used to induce partial tolerance. The suppression of delayed hypersensitivity is antigen-specific in vivo as well as in vitro. The lymphocytes, and not the macrophages, are the cells involved in the induction of tolerance in terms of delayed hypersensitivity which is characterized by an absence of migratory factor activity.


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