Effect of lithium hydroxybutyrate on brain serotonin level in intact rabbits and during hyperactivity of central serotoninergic systems

1983 ◽  
Vol 96 (1) ◽  
pp. 951-953
Author(s):  
A. S. Saratikov ◽  
L. L. Fisanova ◽  
T. A. Zamoshchina
Keyword(s):  
Brain Serotonin ◽  
Serotonin Level ◽  
Lithium Hydroxybutyrate ◽  
Brain Serotonin Level

scholarly journals The Effect of Long-Term Intranasal Serotonin Treatment on Metabolic Parameters and Hormonal Signaling in Rats with High-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes

2015 ◽  
Vol 2015 ◽  
pp. 1-17 ◽  
Author(s):  
Kira V. Derkach ◽  
Vera M. Bondareva ◽  
Oxana V. Chistyakova ◽  
Lev M. Berstein ◽  
Alexander O. Shpakov
Keyword(s):  
Type 2 Diabetes ◽  
High Fat Diet ◽  
Low Dose ◽  
Diabetic Rats ◽  
Brain Serotonin ◽  
Serotonin Level ◽  
High Fat ◽  
Brain Serotonin Level ◽  
The Brain

In the last years the treatment of type 2 diabetes mellitus (DM2) was carried out using regulators of the brain signaling systems. In DM2 the level of the brain serotonin is reduced. So far, the effect of the increase of the brain serotonin level on DM2-induced metabolic and hormonal abnormalities has been studied scarcely. The present work was undertaken with the aim of filling this gap. DM2 was induced in male rats by 150-day high-fat diet and the treatment with low dose of streptozotocin (25 mg/kg) on the 70th day of experiment. From the 90th day, diabetic rats received for two months intranasal serotonin (IS) at a daily dose of 20 μg/rat. The IS treatment of diabetic rats decreased the body weight, and improved glucose tolerance, insulin-induced glucose utilization, and lipid metabolism. Besides, it restored hormonal regulation of adenylyl cyclase (AC) activity in the hypothalamus and normalized AC stimulation byβ-adrenergic agonists in the myocardium. In nondiabetic rats the same treatment induced metabolic and hormonal alterations, some of which were similar to those in DM2 but expressed to a lesser extent. In conclusion, the elevation of the brain serotonin level may be regarded as an effective approach to treat DM2 and its complications.

scholarly journals Cinnabar is Different from Mercuric Chloride in Mercury Absorption and Influence on the Brain Serotonin Level

2013 ◽  
Vol 112 (6) ◽  
pp. 412-417 ◽  
Author(s):  
Qi Wang ◽  
Xiaoda Yang ◽  
Baoxu Zhang ◽  
Xiuwei Yang ◽  
Kui Wang
Keyword(s):  
Mercuric Chloride ◽  
Brain Serotonin ◽  
Serotonin Level ◽  
Brain Serotonin Level ◽  
The Brain

Effect of neonatal β-endorphin imprinting on sexual behavior and brain serotonin level in adult rats

Life Sciences ◽  
2003 ◽  
Vol 73 (1) ◽  
pp. 103-114 ◽  
Author(s):  
G. Csaba ◽  
Barbara Knippel ◽  
Cs. Karabélyos ◽  
Ágnes Inczefi-Gonda ◽  
Monika Hantos ◽  
...  
Keyword(s):  
Sexual Behavior ◽  
Brain Serotonin ◽  
Serotonin Level ◽  
Adult Rats ◽  
Brain Serotonin Level

Effect of Phenylalanine and Its Metabolites on the Brain Serotonin Level of the Rat.

1962 ◽  
Vol 111 (2) ◽  
pp. 444-446 ◽  
Author(s):  
W. J. Culley ◽  
R. N. Saunders ◽  
E. T. Mertz ◽  
D. H. Jolly
Keyword(s):  
Brain Serotonin ◽  
Serotonin Level ◽  
Brain Serotonin Level ◽  
The Brain
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