Diurnal rhythms of function and mitotic activity of the normal and regenerating thyroid gland

1980 ◽  
Vol 89 (4) ◽  
pp. 533-536
Author(s):  
V. A. Glumova ◽  
N. M. Petrov ◽  
M. L. Nikandrovskii ◽  
T. V. Devyatykh
1976 ◽  
Vol 82 (2) ◽  
pp. 517-529 ◽  
Author(s):  
Luis F. Pallardo ◽  
Isabel Pericás ◽  
Trinidad Jolín

ABSTRACT Experiments were performed to assess whether the diurnal changes in thyroid 131I metabolism are paralleled by variations in endogenous iodine. The uptake of iodide by the thyroid gland was determined by a double isotope technique. The T/S iodine ratio and the rate of 131I and 127I secretion from the thyroid gland were determined in rats fed LID during 20 days. The accumulation of iodine by the thyroid gland was prevented by KClO4 and organic iodine formation was blocked by PTU. The absolute uptake of iodide by the thyroid gland was twice as high during the night than during the day. The thyroid/serum iodide ratios were highest during the night. The rate of release of 131I and 127I from the thyroid gland was augmented in the afternoon. The concentration of TSH in the plasma, measured by radioimmunoassay, was elevated in the afternoon as compared to other times during the day and night. The close association between the diurnal changes in thyroid iodine secretion and plasma TSH concentrations suggest that TSH may be responsible for the differences in iodine secretion observed during the day and night. On the other hand, the intake of iodine in the diet and the urinary clearance of iodine showed diurnal rhythms; the highest values occurred during the night. In addition, about twice as much iodine was available to the thyroid gland at night than during the day. These factors might also contribute to the diurnal variations observed in thyroid iodine metabolism.


1971 ◽  
Vol 13 (3) ◽  
pp. 597-599 ◽  
Author(s):  
Richard C. Bishop ◽  
Richard M. Klein

Seeds of Allium cepa were grown in complete darkness at constant temperature. The root tips, collected from hours 72 to 96 after the start of imbibition, exhibited four maxima and four minima in mitotic activity. The timing of this rhythm was dependent upon the time of imbibition and not upon the time of day.


1944 ◽  
Vol 90 (2) ◽  
pp. 133-138 ◽  
Author(s):  
Thomas E. Hunt

Author(s):  
W.T. Gunning ◽  
G.D. Haselhuhn ◽  
E.R. Phillips ◽  
S.H. Selman

Within the last few years, adrenal cortical tumors with features concordant with the diagnostic criteria attributed to oncocytomas have been reported. To date, only nine reported cases exist in the literature. This report is the tenth case presentation of a presumptively benign neoplasm of the adrenal gland with a rare differentiation. Oncocytomas are well recognized benign tumors of the thyroid, parathyroid, and salivary glands and of the kidney. Other organs also give rise to these types of tumors, however with less frequency than the former sites. The characteristics generally used to classify a tumor as an oncocytoma include the following criteria: the tumor is 1) usually a solitary circumscribed mass with no gross nor microscopic evidence of metastasis (no tissue nor vascular invasion), 2) fairly bland in terms of mitotic activity and nuclear morphology, and 3) composed of large eosinophillic cells in which the cytoplasm is packed full of mitochondria (Figure 1).


JAMA ◽  
1967 ◽  
Vol 200 (2) ◽  
pp. 178-179 ◽  
Author(s):  
G. D. Skalkeas
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document