Cytogenetic action of 3-hydroxykynurenin and 3-hydroxyanthranilic acid on human cells in embryonic tissue culture

L. E. Kuznetsova

doi:10.1007/bf00810815

Cytogenetic action of 3-hydroxykynurenin and 3-hydroxyanthranilic acid on human cells in embryonic tissue culture

Bulletin of Experimental Biology and Medicine ◽

10.1007/bf00810815 ◽

1969 ◽

Vol 67 (2) ◽

pp. 200-202 ◽

Cited By ~ 2

Author(s):

L. E. Kuznetsova

Keyword(s):

Tissue Culture ◽

Human Cells ◽

Embryonic Tissue ◽

Hydroxyanthranilic Acid ◽

Cytogenetic Action

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Number of nucleoli in female and male human cells in tissue culture

Experimental Cell Research ◽

10.1016/0014-4827(62)90264-1 ◽

1962 ◽

Vol 28 (3) ◽

pp. 590-592 ◽

Cited By ~ 10

Author(s):

G.B. Petersen ◽

A.J. Therkelsen

Keyword(s):

Tissue Culture ◽

Human Cells

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Viral Susceptibility and Embryonic Differentiation.

Development ◽

10.1242/dev.11.4.757 ◽

1963 ◽

Vol 11 (4) ◽

pp. 757-764

Author(s):

Juhani Rapola ◽

Tapani Vainio ◽

Lauri Saxén

Keyword(s):

Tissue Culture ◽

Viral Replication ◽

Metabolic Rate ◽

Tissue Damage ◽

Embryonic Tissue ◽

High Metabolic Rate ◽

Viral Susceptibility ◽

Proliferative Rate ◽

Active Proliferation ◽

Severe Tissue

The fact that viral susceptibility changes during embryogenesis has been pointed out by both experimental embryologists and clinical practitioners, not to mention virologists working with avian material. In attempts to find the fundamental factors which make embryonic tissue susceptible or resistant to a given virus, the metabolic and proliferative rate have been considered relevant (Williamson et al., 1953; Robertson et al., 1955; Töndury, 1956). Experience accumulated in studies of the replication of various viruses in tissue culture has taught us that a high metabolic rate and active proliferation may not always enhance viral replication (Ginsberg, 1958). However, there seems to be justification for the view that an injurious agent leads to more severe tissue damage when it exercises its effect upon actively proliferating tissues than when it does so at the ‘resting stage’.

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