Plasma amino acids are highly dependent on acid-base balance in uremic rats

Amino Acids ◽  
1992 ◽  
Vol 3 (2) ◽  
pp. 173-182
Author(s):  
N. Gretz ◽  
K. Langer ◽  
M. Strauch
Keyword(s):  
Amino Acids ◽  
Plasma Amino Acids ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

Nitrogen excretion in germ-free and conventional chickens: effects of an alkali load

1978 ◽  
Vol 39 (1) ◽  
pp. 99-104 ◽  
Author(s):  
J. Okumura ◽  
D. Hewitt ◽  
Marie E. Coates
Keyword(s):  
Amino Acids ◽  
Uric Acid ◽  
Ammonia Excretion ◽  
Nitrogen Excretion ◽  
Acid Base Balance ◽  
Acid Base ◽  
Total N ◽  
Germ Free ◽  
Base Balance ◽  
Micro Organisms

1. Groups of three colostomized germ-free (GF) and conventional (CV) chickens aged 4 months were maintained for successive periods of 8 d on a diet containing 200 g casein/kg without and with sodium bicarbonate at the rate of 20 mmol/d and a nitrogen-free diet without and with NaHCO3at 9 mmol/d. Urine and faeces were collected during the last 3 d of each period.2. Total N, uric acid- and ammonia-N were determined in urine and total N in faeces. Amino acids were measured in hydrolysates of faeces collected during the periods when no NaHCO3was included in the diets.3. The CV birds excreted more N on the casein diets but less on the N-free diets than did their GF counterparts, the differences being mainly shown in the urine.4. On both diets hydrolysates of the faeces of CV birds contained smaller amounts of amino acids. On the N-free diet the proportions (g/160 g N) of serine, proline and threonine were reduced, suggesting some conservation of endogenous N by micro-organisms, and the proportions of histidine, alanine, lysine and methionine increased, possibly through microbial synthesis; on the casein diet, proportions of most amino acids were less, probably because bacterial deamination had occurred.5. Urinary excretion of total N, uric acid and ammonia was much greater on the casein than on the N-free diets. Inclusion of NaHCO3caused a sharp fall in urinary ammonia on both diets and in both environments.6. It was concluded that the level of dietary protein and the regulation of acid-base balance have more effect than microbial activity on the urinary ammonia excretion.

Extraction of amino acids from and their addition to renal blood plasma

1963 ◽  
Vol 204 (2) ◽  
pp. 181-186 ◽  
Author(s):  
R. Shalhoub ◽  
W. Webber ◽  
S. Glabman ◽  
M. Canessa-Fischer ◽  
J. Klein ◽  
...  
Keyword(s):  
Amino Acids ◽  
Blood Plasma ◽  
Ammonium Chloride ◽  
Metabolic Alkalosis ◽  
Significant Degree ◽  
Acid Base Balance ◽  
Acid Base ◽  
Paired Samples ◽  
Base Balance ◽  
Venous Plasma

Twenty paired samples of arterial and renal venous plasma, collected simultaneously from dogs in ammonium chloride acidosis, were analyzed by column chromatography for 23 α-amino acids. Fifteen additional paired samples from dogs in acute metabolic alkalosis were similarly analyzed. In ammonium chloride acidosis, glutamine plus asparagine, glycine, citrulline, tryptophan, and proline are extracted from renal blood plasma. Alanine, serine, glutamic acid, cystine, and ornithine are added to renal venous plasma. The addition of glutamic and aspartic acids amounts only to 4% of the extraction of glutamine plus asparagine. It is, therefore, probable that both α-amino and amide nitrogens are removed from the parent amide molecules. In acute metabolic alkalosis, the extraction of glutamine plus asparagine is halved, on an average. The extraction of glycine and the addition of alanine and serine are essentially unchanged. Therefore, only the extraction of glutamine plus asparagine varies to a quantitatively significant degree with changes in acid-base balance which markedly alter the rate of excretion of ammonia.

Higher Dietary Acidity is Associated with Lower Bone Mineral Density in Postmenopausal Iranian Women, Independent of Dietary Calcium Intake

2014 ◽  
Vol 84 (3-4) ◽  
pp. 0206-0217 ◽  
Author(s):  
Seyedeh-Elaheh Shariati-Bafghi ◽  
Elaheh Nosrat-Mirshekarlou ◽  
Mohsen Karamati ◽  
Bahram Rashidkhani
Keyword(s):  
Calcium Intake ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Dietary Intakes ◽  
Iranian Women ◽  
Acid Base Balance ◽  
Mineral Density ◽  
Acid Base ◽  
Base Balance ◽  
Dietary Acid

Findings of studies on the link between dietary acid-base balance and bone mass are relatively mixed. We examined the association between dietary acid-base balance and bone mineral density (BMD) in a sample of Iranian women, hypothesizing that a higher dietary acidity would be inversely associated with BMD, even when dietary calcium intake is adequate. In this cross-sectional study, lumbar spine and femoral neck BMDs of 151 postmenopausal women aged 50 - 85 years were measured using dual-energy x-ray absorptiometry. Dietary intakes were assessed using a validated food frequency questionnaire. Renal net acid excretion (RNAE), an estimate of acid-base balance, was then calculated indirectly from the diet using the formulae of Remer (based on dietary intakes of protein, phosphorus, potassium, and magnesium; RNAERemer) and Frassetto (based on dietary intakes of protein and potassium; RNAEFrassetto), and was energy adjusted by the residual method. After adjusting for potential confounders, multivariable adjusted means of the lumbar spine BMD of women in the highest tertiles of RNAERemer and RNAEFrassetto were significantly lower than those in the lowest tertiles (for RNAERemer: mean difference -0.084 g/cm2; P=0.007 and for RNAEFrassetto: mean difference - 0.088 g/cm2; P=0.004). Similar results were observed in a subgroup analysis of subjects with dietary calcium intake of >800 mg/day. In conclusion, a higher RNAE (i. e. more dietary acidity), which is associated with greater intake of acid-generating foods and lower intake of alkali-generating foods, may be involved in deteriorating the bone health of postmenopausal Iranian women, even in the context of adequate dietary calcium intake.

The Effect of Long-term Topiramate Treatment on Acid-base Balance in Children with Epilepsy

2016 ◽  
Vol 24 (3) ◽  
pp. 116-121
Author(s):  
김지용 ◽  
남상욱 ◽  
김영미 ◽  
이윤진 ◽  
이훈상 ◽  
...  
Keyword(s):  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

scholarly journals THE ACID-BASE BALANCE DISTURBANCE OF PREGNANCY

1932 ◽  
Vol 98 (1) ◽  
pp. 253-260 ◽  
Author(s):  
Victor C. Myers ◽  
Edward Muntwyler ◽  
Arthur H. Bill
Keyword(s):  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance
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