Comparison of the effects of piracetam and N-acetylaspartic acid on memory and on the content of transmitter amino acids in the rat brain during simulation of a neurotic state

1993 ◽  
Vol 116 (5) ◽  
pp. 1393-1395 ◽  
Author(s):  
K. S. Raevskii ◽  
P. A. Nerush
Keyword(s):  
Amino Acids ◽  
Rat Brain ◽  
Transmitter Amino Acids

The effects of halothane on the contents of putative transmitter amino acids in whole rat brain

1990 ◽  
Vol 117 (3) ◽  
pp. 353-357 ◽  
Author(s):  
Toshiyuki Arai ◽  
Motoo Aoki ◽  
Masahiro Murakawa ◽  
Shin-ichi Nakao ◽  
Kenjiro Mori ◽  
...  
Keyword(s):  
Amino Acids ◽  
Rat Brain ◽  
Transmitter Amino Acids

Atypical amino acids inhibit histidine, valine, or lysine transport into rat brain

1983 ◽  
Vol 245 (4) ◽  
pp. R556-R563 ◽  
Author(s):  
J. K. Tews ◽  
A. E. Harper
Keyword(s):  
Amino Acids ◽  
Rat Brain ◽  
Blood Brain Barrier ◽  
Brain Slices ◽  
Aromatic Amino Acids ◽  
Brain Barrier ◽  
Basic Amino Acids ◽  
Large Neutral Amino Acids ◽  
Neutral Amino Acids ◽  
Single Meal

Transport of histidine, valine, or lysine into rat brain slices and across the blood-brain barrier (BBB) was determined in the presence of atypical nonprotein amino acids. Competitors of histidine and valine transport in slices were large neutral amino acids including norleucine, norvaline, alpha-aminooctanoate, beta-methylphenylalanine, and alpha-aminophenylacetate. Less effective were aromatic amino acids with ring substituents; ineffective were basic amino acids and omega-amino isomers of norleucine and aminooctanoate. Lysine transport was moderately depressed by homoarginine or ornithine plus arginine; large neutral amino acids were also similarly inhibitory. Histidine or valine transport across the BBB was also strongly inhibited by large neutral amino acids that were the most effective competitors in the slices (norvaline, norleucine, alpha-aminooctanoate, and alpha-aminophenylacetate); homoarginine and 8-aminooctanoate were ineffective. Homoarginine, ornithine, and arginine almost completely blocked lysine transport, but the large neutral amino acids were barely inhibitory. When rats were fed a single meal containing individual atypical large neutral amino acids or homoarginine, brain pools of certain large neutral amino acids or of arginine and lysine, respectively, were depleted.

Acute effects of aspartame on large neutral amino acids and monoamines in rat brain

Life Sciences ◽  
1983 ◽  
Vol 32 (14) ◽  
pp. 1651-1658 ◽  
Author(s):  
John D. Fernstrom ◽  
Madelyn H. Fernstrom ◽  
Marcia A. Gillis
Keyword(s):  
Amino Acids ◽  
Rat Brain ◽  
Acute Effects ◽  
Large Neutral Amino Acids ◽  
Neutral Amino Acids

scholarly journals Manganese Alters Rat Brain Amino Acids Levels

2012 ◽  
Vol 150 (1-3) ◽  
pp. 337-341 ◽  
Author(s):  
Dinamene Santos ◽  
M. Camila Batoreu ◽  
Isabel Almeida ◽  
Ruben Ramos ◽  
M. Sidoryk-Wegrzynowicz ◽  
...  
Keyword(s):  
Amino Acids ◽  
Rat Brain

Determination of amino acids in different regions of the rat brain application to the acute effects of tetrahydrocannabinol (THC) and trimethyltin (TMT)

Life Sciences ◽  
1988 ◽  
Vol 42 (20) ◽  
pp. 2029-2035 ◽  
Author(s):  
Ahmed H. Hikal ◽  
George W. Lipe ◽  
William Slikker ◽  
Andrew C. Scallet ◽  
Syed F. Ali ◽  
...  
Keyword(s):  
Amino Acids ◽  
Rat Brain ◽  
Acute Effects

RP-LC with Fluorescence Detection of Amino Acids in Rat Brain Synaptosomes

2011 ◽  
Vol 73 (1-2) ◽  
pp. 157-163 ◽  
Author(s):  
Xiaoyuan Mao ◽  
Yonggang Cao ◽  
Dongyu Min ◽  
Feng Guo ◽  
Ni Xie ◽  
...  
Keyword(s):  
Amino Acids ◽  
Rat Brain ◽  
Fluorescence Detection ◽  
Rat Brain Synaptosomes ◽  
Brain Synaptosomes
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