Organ cultures of embryonic liver synthesizing serum proteins

1969 ◽  
Vol 67 (3) ◽  
pp. 310-312
Author(s):  
E. A. Luriya ◽  
R. D. Bakirov ◽  
G. I. Abelev ◽  
A. Ya. Fridenshtein
Keyword(s):  
Serum Proteins ◽  
Embryonic Liver ◽  
Organ Cultures

Establishment of organ cultures of human embryonic liver for growth of viruses

1972 ◽  
Vol 37 (2-3) ◽  
pp. 230-235 ◽  
Author(s):  
Pamela M. Baines ◽  
Patricia E. Taylor ◽  
A. J. Zuckerman
Keyword(s):  
Embryonic Liver ◽  
Organ Cultures

Differentiation of hepatic and hematopoietic cells and synthesis of blood serum proteins in organ cultures of the liver

1969 ◽  
Vol 54 (1) ◽  
pp. 111-117 ◽  
Author(s):  
E.A. Luria ◽  
R.D. Bakirov ◽  
T.A. Yeliseyeva ◽  
G.I. Abelev ◽  
A.Y. Friedenstein
Keyword(s):  
Blood Serum ◽  
Serum Proteins ◽  
Hematopoietic Cells ◽  
Organ Cultures ◽  
Blood Serum Proteins

Colony-forming cells in organ cultures of embryonic liver

1969 ◽  
Vol 68 (1) ◽  
pp. 785-787
Author(s):  
N. V. Latsinik ◽  
E. A. Luriya ◽  
N. A. Samoilina ◽  
A. Ya. Fridenshtein ◽  
I. L. Chertkov
Keyword(s):  
Embryonic Liver ◽  
Organ Cultures

Fine Structural Alterations in Thyroid Follicular Cells (FC) and Changes in Serum Thyroxine Produced by Feeding Polychlorinated Biphenyl (PCB) to Rats

1977 ◽  
Vol 35 ◽  
pp. 498-499
Author(s):  
W.T. Collins ◽  
Charles C. Capen ◽  
Louis Kasza
Keyword(s):  
Feed Efficiency ◽  
Polychlorinated Biphenyl ◽  
Serum Proteins ◽  
Skin Lesions ◽  
Hepatic Necrosis ◽  
Ultrastructural Changes ◽  
Lymphoid Tissues ◽  
Heat Transfer Fluids ◽  
Thyroid Follicular Cells ◽  
Peripheral Metabolism

The widespread contamination of the environment with PCB, a compound used extensively by industry in hydraulic and heat transfer fluids as well as plasticizers and solvents in adhesives and sealants, has resulted in detectable tissue levels in a large portion of the human population, domestic animals, and wildlife. Intoxication with PCB produces severe hepatic necrosis, degeneration of lymphoid tissues and kidney, skin lesions, decreased reproductive performance, reduced feed efficiency, and decreased weight gain. PCB also has been reported to reduce the binding of thyroid hormone to serum proteins and enhance the peripheral metabolism of thyroxine with increased excretion of thyroxine-glucuronide in the bile (Bastomsky, Endocrinology 95: 1150-1155, 1974).The objectives of this investigation were (1) to investigate the histopathologic, histochemical, and ultrastructural changes in thyroid FC produced by the acute (4 week) and chronic (12 week) administration of low (50 ppm) and high (500 ppm) doses of PCB to rats, (2) to correlate these alterations to changes in serum immunoreactive thyroxine concentration, and (3) to investigate the persistence of the effects of PCB on the thyroid gland.

Scanning Microscopy of Human Intestinal Explants in Organ Culture

1972 ◽  
Vol 30 ◽  
pp. 396-397
Author(s):  
Bruce Wetzel ◽  
Robert Buscho ◽  
Raphael Dolin
Keyword(s):  
Electron Microscopy ◽  
Room Temperature ◽  
Culture Conditions ◽  
Human Fetuses ◽  
Enteric Disease ◽  
Organ Cultures ◽  
Growth Of A Variety ◽  
Normal Human ◽  
Fetal Intestine ◽  
Scanning Electron

It has been reported that explants of human fetal intestine can be maintained in culture for up to 21 days in a viable condition and that these organ cultures support the growth of a variety of known viral agents responsible for enteric disease. Scanning electron microscopy (SEM) has been undertaken on several series of these explants to determine their appearance under routine culture conditions.Fresh specimens of jejunum obtained from normal human fetuses were washed, dissected into l-4mm pieces, and cultured in modified Leibowitz L-15 medium at 34° C as previously described. Serial specimens were fixed each day in 3% glutaraldehyde for 90 minutes at room temperature, rinsed, dehydrated, and dried by the CO2 critical point method in a Denton DCP-1 device. Specimens were attached to aluminum stubs with 3M transfer tape No. 465, and one sample on each stub was carefully rolled along the adhesive such that villi were broken off to expose their interiors.

Serum Proteins in Ulcerative Colitis

1959 ◽  
Vol 37 (3) ◽  
pp. 263-267 ◽  
Author(s):  
Richard O. Bicks ◽  
Joseph B. Kirsner ◽  
Walter L. Palmer
Keyword(s):  
Ulcerative Colitis ◽  
Serum Proteins
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