Effect of intrautreine hypoxia on protein synthesis in different parts of the brain and on tissue-blood barrier function in later stages of development in rats

1977 ◽  
Vol 84 (4) ◽  
pp. 1409-1412
Author(s):  
M. Ya. Maizelis ◽  
A. L. Zablyudovskii
Neurosignals ◽  
1996 ◽  
Vol 5 (6) ◽  
pp. 343-348 ◽  
Author(s):  
Wei Ping Li ◽  
Helen W.L. Lai ◽  
Suet Ying Cheng ◽  
David T. Yew

Development ◽  
1973 ◽  
Vol 29 (2) ◽  
pp. 267-281
Author(s):  
G. Teitelman

Removal of the polar lobe at the trefoil stage of the first cleavage division of Ilyanassa embryos causes abnormalities much later in development. To determine if the developmental differences between normal and delobed embryos were reflected in alterations in protein synthesis and at what stages of development these become evident, protein solutions were separated by disc electrophoresis on basic acrylamide gels. For the analysis of the newly synthesized proteins, two protein samples, one labelled with 14C and the other with 3H, were combined in the same electrophoretic column. Each was prepared from normal embryos or lobeless embryos at different stages of development. The distribution of the two groups of differentially labelled proteins was compared by a determination, for each fraction, of the ratio of the normalized 3H/14C counts for that particular fraction (R = 3H/14C). The plot of R versus fraction number was studied for various combinations of samples. During normal development the profile of labelled proteins remains unchanged until the onset of visible differentiation. At this stage, around day 4 of development, there are changes in biosynthesis revealed by a greater emphasis on the synthesis of slow moving proteins. The profile of labelled proteins of lobeless embryos remains unchanged up to the 5th day of development. This result is correlated with the absence, in the lobeless embryos, of many of the visible differentiations. Preliminary studies revealed that the spectrum of labelled proteins of the polar lobe is identical to the one present in lobeless embryos and in normal embryos in early stages of development. This suggests the possibility that the morphogenetic factors associated with the polar lobe are not among the newly synthesized proteins. A hypothesis is presented to account for the effects on morphogenesis and protein synthesis which are produced by removal of the polar lobe.


2009 ◽  
Vol 55 (1) ◽  
pp. 75-80 ◽  
Author(s):  
Kazuyo TUJIOKA ◽  
Miho OHSUMI ◽  
Kenji HORIE ◽  
Mujo KIM ◽  
Kazutoshi HAYASE ◽  
...  

2018 ◽  
Vol 100 (4) ◽  
pp. 13-17
Author(s):  
Maryanne Wolf

Because reading is not a natural process like language, young learners must be taught to read. Knowledge about how the reading brain develops has critical implications for understanding which teaching methods to use and helps reconceptualize previous debates. In this excerpt from Reader Come Home: The Reading Brain in a Digital World, Maryanne Wolf describes how many different parts of the brain must work together when reading and why each requires attention in teaching. She delves into research into different reader profiles, each of which needs different emphases in reading instruction, and she explains the value of teaching approaches that include both explicit instruction in decoding and deep reading processes, and engagement by learner and teacher with the world of words and stories.


2016 ◽  
Vol 31 (2) ◽  
pp. 77-83
Author(s):  
KaYan KaYan ◽  
Henndy Ginting ◽  
Cakrangadinata Cakrangadinata

A number of research findings have found the impact of emotion on memory. Some researchers stated that disgust has more impact on memory, however according to the current study the effect of fear cannot be ignored. Both disgust and fear are examples of negative emotion that may have a significant influence on behavior, such as in the attempt of creating a healthy lifestyle. The current study involved an experiment where participants were asked to memorize and recall four randomly displayed picture categories that elicit emotions of disgust, fear, joy, and neutral emotion. They also filled out a DS-R (Disgust Scale-Revised) questionnaire and a supporting questionnaire about healthy lifestyle. Analysis of the results showed that disgust did not show an effect on memory, but fear instead did. This is related to the fact that most participants showed a low degree of disgust, and so it was not considered a significant emotion that affected memory compared to fear. In addition, physiologically fear and disgust are managed by different parts of the brain and thus it was assumed that they will have a different impact on memory. The findings implied that, in campaigning for a healthier lifestyle, fear emotion need to be instilled in people.


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