Morphometry of the juxtaglomerular apparatus of the allografted human kidney

1976 ◽  
Vol 81 (1) ◽  
pp. 108-110
Author(s):  
S. L. Orduyan ◽  
V. N. Blyumkin
Keyword(s):  
Human Kidney ◽  
Juxtaglomerular Apparatus

The Juxtaglomerular Apparatus in a Human Kidney with Polar Artery Stenosis

2009 ◽  
Vol 86A (1-6) ◽  
pp. 375-381
Author(s):  
J. A. Christensen ◽  
D. S. Meyer ◽  
H. D. Jakubowski ◽  
J. Neuenhöfer ◽  
A. Bohle
Keyword(s):  
Human Kidney ◽  
Juxtaglomerular Apparatus ◽  
Artery Stenosis

scholarly journals Use of a specific antiserum for renin detection in human kidney.

1980 ◽  
Vol 28 (12) ◽  
pp. 1343-1346 ◽  
Author(s):  
J P Camilleri ◽  
V N Phat ◽  
J Bariety ◽  
P Corvol ◽  
J Menard
Keyword(s):  
Human Kidney ◽  
Juxtaglomerular Apparatus ◽  
Specific Antiserum ◽  
Normal Kidney ◽  
Proximal Tubular Cells ◽  
Tubular Cells ◽  
Human Renin ◽  
Proximal Tubular ◽  
Afferent Arterioles

The use of anti-human renin antibodies made possible the intrarenal localization of renin in human kidney by immunofluorescence. In normal kidney, only some juxtaglomerular apparatus (JGA) were fluorescent. In these JGA, granular or diffuse fluorescence was only seen in afferent arterioles and was not present in all cells. In the ischemic areas of partially infarcted kidney, fluorescence was seen in all JGA and in interlobular arteries. In these arteries the most eccentric cells were often the most positive. In the nonischemic areas of the same kidneys, fluorescence was not seen in JGA, but was observed in proximal tubular cells, suggesting the reabsorption of filtered renin at this site.

The normal juxtaglomerular apparatus in the human kidney

1979 ◽  
Vol 103 (4) ◽  
pp. 374-383 ◽  
Author(s):  
Jan A. Chrístensen ◽  
Håkon A. Bjærke ◽  
Dieter S. Meyer ◽  
Adalbert Bohle
Keyword(s):  
Human Kidney ◽  
Juxtaglomerular Apparatus

1107: Evaluation of Cystine Transport in Cultured Human Kidney Cells: Primer to Gene Therapy of Cystinuria

2005 ◽  
Vol 173 (4S) ◽  
pp. 300-300
Author(s):  
Sreedhar Sagi ◽  
Lutz Trojan ◽  
Peter Aiken ◽  
Maurice S. Michel ◽  
Thomas Knoll
Keyword(s):  
Gene Therapy ◽  
Human Kidney ◽  
Kidney Cells

378: 14-3-3 Expression Patterns in the Human Kidney: From Fetal Development to the Adult State to Malignant Transformation

2005 ◽  
Vol 173 (4S) ◽  
pp. 103-103
Author(s):  
Adam G. Baseman ◽  
Andrew J. Kirsch ◽  
Fray F. Marshall ◽  
Haiyen E. Zhau ◽  
Leland W.K. Chung ◽  
...  
Keyword(s):  
Malignant Transformation ◽  
Fetal Development ◽  
Expression Patterns ◽  
Human Kidney

PROPERTIES OF SPECIFIC ESTROGEN-BINDING COMPONENTS IN HUMAN KIDNEY AND RENAL CARCINOMA

1975 ◽  
Vol 80 (1_Suppla) ◽  
pp. S51 ◽  
Author(s):  
H. Bojar ◽  
J. L. Wittliff ◽  
K. Balzer ◽  
R. Dreyfürst ◽  
F. Boeminghaus ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Human Kidney ◽  
Estrogen Binding

Spatial Metabolomics of the Human Kidney Using MALDI Trapped Ion Mobility Imaging Mass Spectrometry

2020 ◽  
Author(s):  
Elizabeth Neumann ◽  
Lukasz Migas ◽  
Jamie L. Allen ◽  
Richard Caprioli ◽  
Raf Van de Plas ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility ◽  
Imaging Mass Spectrometry ◽  
Structural Complexity ◽  
Human Kidney ◽  
Resolving Power ◽  
Mobility Separation ◽  
Trapped Ion ◽  
Mobility Data ◽  
Ion Mobility Separation

<div> <div> <p>Small metabolites are essential for normal and diseased biological function but are difficult to study because of their inherent structural complexity. MALDI imaging mass spectrometry (IMS) of small metabolites is particularly challenging as MALDI matrix clusters are often isobaric with metabolite ions, requiring high resolving power instrumentation or derivatization to circumvent this issue. An alternative to this is to perform ion mobility separation before ion detection, enabling the visualization of metabolites without the interference of matrix ions. Here, we use MALDI timsTOF IMS to image small metabolites at high spatial resolution within the human kidney. Through this, we have found metabolites, such as arginic acid, acetylcarnitine, and choline that localize to the cortex, medulla, and renal pelvis, respectively. We have also demonstrated that trapped ion mobility spectrometry (TIMS) can resolve matrix peaks from metabolite signal and separate both isobaric and isomeric metabolites with different localizations within the kidney. The added ion mobility data dimension dramatically increased the peak capacity for molecular imaging experiments. Future work will involve further exploring the small metabolite profiles of human kidneys as a function of age, gender, and ethnicity.</p></div></div>

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