Effect of human tonsillar lymphocyte extract on the macrophage migration inhibition test in guinea pigs exposed to various antigens

1978 ◽  
Vol 86 (2) ◽  
pp. 1058-1060
Author(s):  
N. V. Medunitsyn ◽  
A. N. Mats ◽  
O. V. Protasova
Keyword(s):  
Guinea Pigs ◽  
Inhibition Test ◽  
Macrophage Migration ◽  
Migration Inhibition ◽  
Macrophage Migration Inhibition

Is injectable collagen truly safe?

1992 ◽  
Vol 106 (8) ◽  
pp. 704-708 ◽  
Author(s):  
Etsuyo Takayama ◽  
Makoto Ikeda ◽  
Sumiaki Tsuru ◽  
Masami Ogura ◽  
Satoshi Kitahara ◽  
...  
Keyword(s):  
Allergic Reaction ◽  
Positive Response ◽  
Inhibition Test ◽  
Macrophage Migration ◽  
Potential Hazard ◽  
Migration Inhibition ◽  
Injectable Collagen ◽  
Macrophage Migration Inhibition

AbstractMost patients have no response to injectable collagen or silicone, but some cases may have positive or ‘undersea’(= clinically negative but immunologically positive) response to collagen. From the results of the Macrophage migration inhibition test, the relative immunogenicity was augmented most when we used implants with the following combination. The firstimmunization was collagen and the second one was collagen with silicone.The augmented antigenicity might be enough to cause an allergic reaction to the patients who had no response to each implant alone. The purpose of this article is to warn of the potential hazard of injection.

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