The blood-clearing factor in acute experimental toxic hepatitis

1964 ◽  
Vol 58 (2) ◽  
pp. 920-922
Author(s):  
S. I. Dudarova
2007 ◽  
Vol 6 (4) ◽  
pp. 46-52
Author(s):  
V. S. Chuchalin ◽  
Ye. M. Teplyakova

The influence of complex herbal remedy on the secretary and metabolic functions of a liver was investigated in rates with experimental toxic hepatitis and hypercholesterolemia. The result obtained have shown that complex herbal remedy shortened the time of evolution and decreased hepatic enzymes (AST, ALT, and GGT), alkaline phosphates, total bilirubin, and cholesterol. It has also been shown that complex herbal remedy increased the protein synthesis of hepatocyte and hampered lipolysis processes. On the other hand, the active components of this remedy regulated the excessive bile production. During complex herbal remedy administration, the rheologycal properties of bile are normalized, bile acid pool extends, and total cholesterol in bile reduces. Along with hepatoprotective properties, remedy has the expressive choleretic and cholekinetic effects.


2009 ◽  
Vol 3 (6) ◽  
pp. 565-572
Author(s):  
E. V. Baidyuk ◽  
A. P. Shiryaeva ◽  
N. N. Bezborodkina ◽  
G. A. Sakuta

2015 ◽  
Vol 2015 (2) ◽  
pp. 19-27 ◽  
Author(s):  
B. KONDRATSKYI ◽  
◽  
V. NOVAK ◽  
Ya. KONDRATSKYI ◽  
D. KACHMARYK ◽  
...  

2016 ◽  
Vol 50 (7) ◽  
pp. 451-457 ◽  
Author(s):  
N. I. Kulesh ◽  
S. A. Fedoreev ◽  
M. V. Veselova ◽  
N. F. Kushnerova ◽  
S. E. Fomenko ◽  
...  

2007 ◽  
Vol 6 (2) ◽  
pp. 11-16
Author(s):  
L. V. Vokhmintseva ◽  
N. N. Mayanskaya ◽  
S. S. Rymar′ ◽  
P. A. Zheleznyi ◽  
A. P. Nadeyev ◽  
...  

Experimental toxic hepatitis was induced by single administration of Acetaminophen ( paracetamol) in a dose of 1000 mg per 1 kg of body mass in Wistar rats. Inflammation pathology was modeled by wounding the upper maxilla gingiva in toxic hepatitis rats on the 6-th day. Intact rats were controls. On the 1-st and 7-th day, ratio of neutrophil-macrophag was determined in smears of the upper maxillas gingival, oxygen-dependent functional activity of neutrophils was assessed based upon HST-test, functional activity reserves were assessed by the stimulation index. On the 7-th and 13-th day, alaninaminotransferase and aspartataminotransferase activity, level of general and indirect bilirubin, general blood protein were assessed in blood serum of these rats. Toxic hepatitis was established to be accomplished by increased biocidity of phagocytes, decreased functional reserves of neutrophils and their migration into the parodontium. In experimental inflammation, suppurative processes in parodontium tissues are revealed in toxic hepatitis rats by 1.5 times less than in controls due to lower biocide activity of phagocyte cells and increased migration of macrophages.


2015 ◽  
Vol 17 (3) ◽  
Author(s):  
М. І. Koval

<p>The efficacy of simultaneous administration of enterosorbent “Enterosgel” and dietary supplement “Alpha+Omega”<br />in age aspect decreased like that: 1‑month &gt; 6‑month &gt; 12‑month. Such dynamics correlates with degree of rising of<br />enzymes activity (AST, ALT and alkaline phosphatase) in rats blood plasma, which had acute Paracetamol poisoning<br />compared with the intact rats. Such way of correction of ALT, AST and alkaline phosphatase activity in experiment<br />with Paracetamol poisoning can be used for further studying of experimental toxic hepatitis.</p>


1971 ◽  
Vol 71 (4) ◽  
pp. 367-369
Author(s):  
B. L. Lempert ◽  
M. B. Sheikman ◽  
T. S. Petrova ◽  
M. G. Zaslavskaya

Sign in / Sign up

Export Citation Format

Share Document