Diurnal changes in the number of mitoses and of DNA-synthesizing cells in tissues of young rats

1976 ◽  
Vol 82 (5) ◽  
pp. 1712-1714 ◽  
Author(s):  
N. G. Bystrenina ◽  
G. I. Podderyugina
Keyword(s):  
Diurnal Changes ◽  
Young Rats

On the Fibrinolytic System in Aged Rats, and Its Reactivity to Endotoxin and Cytokines

1992 ◽  
Vol 67 (06) ◽  
pp. 697-701 ◽  
Author(s):  
J J Emeis ◽  
A Brouwer ◽  
R J Barelds ◽  
M A Horan ◽  
S K Durham ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Fibrinolytic Activity ◽  
Fibrinolytic System ◽  
Tissue Type ◽  
High Dose ◽  
Base Line ◽  
Aged Rats ◽  
Tissue Type Plasminogen Activator ◽  
Young Rats ◽  
Type Plasminogen Activator

SummaryAged rats are more susceptible to endotoxin-induced effects, including microthrombosis and platelet aggregation, than are young rats. To investigate whether changes in the fibrinolytic system might be involved, we investigated the fibrinolytic activity in plasma euglobulin fractions and tissues (lung and heart) of young (6-months old) and aged (24-months old) rats under baseline conditions and after challenge with endotoxin. Aged rats had lower plasma levels of tissue-type plasminogen activator (t-PA) and of urokinase-type PA (u-PA) activity. PA inhibitor (PAI) activity was higher in the plasma of aged rats, as was t-PA activity in lung and heart.Rats were treated with either a low dose (1 μg/kg) or a high dose (10 mg/kg) of endotoxin. Both treatments induced a transient phase of increased blood fibrinolytic activity, as evidenced by higher levels of tissue-type plasminogen activator (t-PA) activity and decreased levels of PA inhibitor (PAI) activity. Over time, the fibrinolytic activity decreased, probably due to increased levels of PA inhibitor.Both the early increase in t-PA activity, and the subsequent increase in PAI activity, were more pronounced in the aged rats, as compared with the younger rats, after the high dose of endotoxin. The aged rats also responded to an injection of interleukin-1β or tumor necrosis factor-α with a larger increase of PAI activity than did the younger rats.Together the data suggest that, compared to young rats, aged rats have a decreased base-line plasma fibrinolytic activity, while their fibrinolytic system is more responsive to challenge by endotoxin and cytokines.

Effect of KH-305 on the Nitric Oxide Synthase Activity and Erectile Dysfunction in Young Rats

2007 ◽  
Vol 36 (3) ◽  
pp. 305-310 ◽  
Author(s):  
Eun-Jeong Lee ◽  
Hee-Seok Kim ◽  
Byoung-Chul Kim ◽  
Sung-Wan Hwang ◽  
Sung-Yeoun Hwang
Keyword(s):  
Nitric Oxide ◽  
Erectile Dysfunction ◽  
Nitric Oxide Synthase ◽  
Young Rats ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

Water Relations of Field Grown Cotton and Sorghum: Temporal and Diurnal Changes in Leaf Water, Osmotic, and Turgor Potentials 1

Crop Science ◽  
1977 ◽  
Vol 17 (1) ◽  
pp. 76-80 ◽  
Author(s):  
R. C. Ackerson ◽  
D. R. Krieg ◽  
T. D. Miller ◽  
R. E. Zartman
Keyword(s):  
Water Relations ◽  
Leaf Water ◽  
Diurnal Changes

System Identification and Control of the Activated Sludge Process by Use of a Statistical Model

1989 ◽  
Vol 21 (10-11) ◽  
pp. 1161-1172 ◽  
Author(s):  
M. Hiraoka ◽  
K. Tsumura
Keyword(s):  
Control System ◽  
System Identification ◽  
Statistical Model ◽  
Activated Sludge ◽  
Sewage Treatment Plant ◽  
Treatment Plant ◽  
Ar Model ◽  
Diurnal Changes ◽  
Activated Sludge Process ◽  
And Control

The authors have been developing a hierarchical control system for the activated sludge process which consists of an upper level system controlling long-term seasonal variations, a control system of intermediate level aiming at optimization of the process and a control system of lower level controlling diurnal changes or hourly fluctuations. The control system using the multi-variable statistical model is one of the most appropriate control systems based on the modern control theory, for applying the lower level control of the activated sludge process. This paper introduces our efforts for developing the reliable data acquisition system, the control experiments applying the AR-model, one of the statistical models which were conducted at a pilot plant and present studies on the system identification and control at a field sewage treatment plant.

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