The histophysiology of the intermediate lobe of the hypophysis in relation to hypothalamic neurosecretion

1963 ◽  
Vol 53 (3) ◽  
pp. 330-334
Author(s):  
A. A. Voitkevich ◽  
E. L. Soboleva
1986 ◽  
Vol 113 (4) ◽  
pp. 471-478 ◽  
Author(s):  
R. J. Kemppainen ◽  
J. L. Sartin

Abstract. In order to examine regulation of pituitary intermediate lobe secretion, plasma immunoreactive (i)ACTH, cortisol, and α-MSH responses to iv bolus injections of CRF, quipazine maleate (serotonin agonist), isoproterenol (β-adrenergic agonist) or haloperidol (dopamine antagonist) were determined in conscious, unrestrained dogs. Endocrine responses to these test substances were also determined in dogs pre-treated with dexamethasone. Administration of one or more doses of each test substance resulted in significant elevations in plasma iACTH and cortisol concentrations. Only haloperidol injection caused significant increases in plasma iα-MSH. Following dexamethasone pre-treatment, plasma iACTH and cortisol increases in response to all test substances were considerably reduced or abolished. Dexamethasone did not alter baseline or haloperidol-stimulated plasma ia-MSH concentrations. However, infusion of bromocriptine mesylate (dopamine agonist) in combination with dexamethasone pre-treatment reduced the plasma iα-MSH response to haloperidol. We conclude that a dopaminergic pathway is important in the in vivo regulation of pituitary intermediate lobe activity in dogs.


1985 ◽  
Vol 260 (15) ◽  
pp. 8956-8963
Author(s):  
Y P Loh ◽  
B Myers ◽  
B Wong ◽  
D C Parish ◽  
M Lang ◽  
...  

1956 ◽  
Vol 3 (4) ◽  
pp. 264-271
Author(s):  
TAKASHI YAMADA ◽  
SUSUMU KANEKO ◽  
KUNIHIRO SUGIYAMA

1967 ◽  
Vol 123 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Kamla Kripalani ◽  
Asok Ghosh ◽  
Hamidur Rahman

2009 ◽  
Vol 84 (06) ◽  
pp. 338-345 ◽  
Author(s):  
Ilona Fazekas ◽  
Hedvig Medzihradszky-Schweiger ◽  
G. Rappay ◽  
Zsuzsanna Acs ◽  
M. Fekete ◽  
...  
Keyword(s):  

1988 ◽  
Vol 47 (2) ◽  
pp. 95-101 ◽  
Author(s):  
Jean-Philippe Loeffler ◽  
Barbara A. Demeneix ◽  
Nikolai A. Kley ◽  
Volker Höllt

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