Electrometric method of continuous recording of the volume velocity of the blood flow and changes in the total volume of blood in the human lungs

1967 ◽  
Vol 63 (3) ◽  
pp. 324-327
Author(s):  
B. I. Mazhbich
Keyword(s):  
Blood Flow ◽  
Continuous Recording ◽  
Electrometric Method ◽  
Volume Velocity ◽  
Human Lungs

Pericytes within a pulmonary neurovascular unit in coronavirus disease 2019-elicited pathological changes

2020 ◽  
Vol 17 ◽  
Author(s):  
Zhen He
Keyword(s):  
Blood Flow ◽  
Physiological Function ◽  
Neurovascular Unit ◽  
Microvascular Blood Flow ◽  
Pathological Changes ◽  
Blood Oxygen Saturation ◽  
Oxygen Saturation Level ◽  
Disease States ◽  
Human Lungs ◽  
High Altitude Illness

: A pericyte-centered theory suggesting that embolisms occurring within the microvasculature of a neurovascular unit can result in either parenchymal hemorrhage or intravascular congestion is presented here. Dysfunctional microvascular pericytes are characterized by their location in the neurovascular unit, either on the arteriole or venule side. Pathophysiological and pathological changes caused by coronavirus disease 2019 (COVID-19) include pulmonary hypertension, edema, focal hemorrhage, microvascular congestion, and thrombosis. In this paper, I have extended the application of the pericytes-centered hypothesis to COVID-19 by proposing the concept of a pulmonary neurovascular unit (pNVU); application of this concept implies that human lungs contain approximately 300 million pNVUs. This concept of existing local regulation of microvascular blood flow is supported by the observation of pathophysiology in pulmonary embolism and in acute high-altitude illness. The autonomic control seen in these three disease states matches blood flow with oxygen supply in each pNVU to maintain physiological blood oxygen saturation level. Here, I illustrate how the malfunction of microvascular pericytes may cause focal hemorrhage, edema or microvascular congestion and thrombosis. A bypass existing in each pNVU would autonomically deviate blood flow from a COVID-19-affected pNVU to other healthy pNVUs. This action would prevent systemically applied medicines from reaching the therapeutic threshold in COVID-19- affected pNVUs. While testing this hypothesis with experimental evidence is urgently needed, supporting therapy aimed at improving microcirculation or rebuilding the physiological function of microvascular pericytes is recommended as a potentially effective treatment of COVID 19.

Continuous recording of cerebral blood flow by means of a thermal diffusion method using a Peltier stack

Neurosurgery ◽  
1987 ◽  
Vol 21 (5) ◽  
pp. 693???8 ◽  
Author(s):  
K Koshu ◽  
S Hirota ◽  
M Sonobe ◽  
S Takahashi ◽  
A Takaku ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Thermal Diffusion ◽  
Continuous Recording ◽  
Diffusion Method ◽  
Thermal Diffusion Method

scholarly journals Continuous Recording of Cerebral Blood Flow by Means of Thermal Diffusion Method using Peltier Stack

1987 ◽  
Vol 27 (8) ◽  
pp. 724-728
Author(s):  
Keiji KOSHU ◽  
Shigeru HIROTA ◽  
Makoto SONOBE ◽  
Shinichiro TAKAHASHI ◽  
Akira TAKAKU ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Thermal Diffusion ◽  
Continuous Recording ◽  
Diffusion Method ◽  
Thermal Diffusion Method
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