Some peculiarities of metastasis formation by experimental tumors

1959 ◽  
Vol 47 (1) ◽  
pp. 62-65 ◽  
Author(s):  
M. S. Lomakin
Keyword(s):  
Metastasis Formation ◽  
Experimental Tumors

57Co-Hematoporphyrin Accumulation by Experimental Tumors

1976 ◽  
Vol 15 (04) ◽  
pp. 183-184 ◽  
Author(s):  
L. J. Anghileri ◽  
M. Heidbreder ◽  
R. Mathes
Keyword(s):  
Experimental Tumors ◽  
Potential Value ◽  
Tumor Bearing ◽  
In Vivo Distribution

SummaryThe in vivo distribution of 57Co-hematoporphyrin in adenocarcinoma BW10232-bearing mice has been studied. Tumor-bearing and normal animals exhibit similar patterns of radioactivity accumulation. Twenty-four hours after the administration of the radiocompound the ratios tumor to blood and tumor to muscle indicate a potential value of this radioactive porphyrin for the detection of some types of tumor.

Resident Memory T Cells in Tumor-Distant Tissues Fortify Against Metastasis Formation

2020 ◽  
Author(s):  
Laura S. Christian ◽  
liuyang wang ◽  
Haiyang Wu ◽  
Dachuan Deng ◽  
Bryan Lim ◽  
...  
Keyword(s):  
T Cells ◽  
Memory T Cells ◽  
Metastasis Formation ◽  
Resident Memory T Cells

scholarly journals Integrative Genomic Analyses of Patient-Matched Intracranial and Extracranial Metastases Reveal a Novel Brain-Specific Landscape of Genetic Variants in Driver Genes of Malignant Melanoma

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 731
Author(s):  
Renáta Váraljai ◽  
Susanne Horn ◽  
Antje Sucker ◽  
Daniela Piercianek ◽  
Verena Schmitt ◽  
...  
Keyword(s):  
Brain Metastases ◽  
Genetic Variants ◽  
Genetic Alterations ◽  
Metastasis Formation ◽  
Driver Genes ◽  
Targeted Next Generation Sequencing ◽  
Paired Samples ◽  
Melanoma Metastases ◽  
Frequent Event ◽  
Genetic Landscape

Background: Development of brain metastases in advanced melanoma patients is a frequent event that limits patients’ quality of life and survival. Despite recent insights into melanoma genetics, systematic analyses of genetic alterations in melanoma brain metastasis formation are lacking. Moreover, whether brain metastases harbor distinct genetic alterations beyond those observed at different anatomic sites of the same patient remains unknown. Experimental Design and Results: In our study, 54 intracranial and 18 corresponding extracranial melanoma metastases were analyzed for mutations using targeted next generation sequencing of 29 recurrently mutated driver genes in melanoma. In 11 of 16 paired samples, we detected nucleotide modifications in brain metastases that were absent in matched metastases at extracranial sites. Moreover, we identified novel genetic variants in ARID1A, ARID2, SMARCA4 and BAP1, genes that have not been linked to brain metastases before; albeit most frequent mutations were found in ARID1A, ARID2 and BRAF. Conclusion: Our data provide new insights into the genetic landscape of intracranial melanoma metastases supporting a branched evolution model of metastasis formation.

αvβ5-Integrins mediate early steps of metastasis formation

2005 ◽  
Vol 41 (7) ◽  
pp. 1065-1072 ◽  
Author(s):  
Andreas Enns ◽  
Timo Korb ◽  
Kerstin Schlüter ◽  
Peter Gassmann ◽  
Hans-Ullrich Spiegel ◽  
...  
Keyword(s):  
Metastasis Formation

Effects of thymic factors on growth of experimental tumors

1980 ◽  
Vol 13 (4) ◽  
pp. 329-335 ◽  
Author(s):  
L. J. Anghileri ◽  
N. Kelemen ◽  
F. Lasmoles ◽  
J. N. Talbot ◽  
G. Milhaud
Keyword(s):  
Experimental Tumors
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