Interaction of certain xenobiotics with living cells: Investigation by the method of fluorescent probes

1982 ◽  
Vol 16 (12) ◽  
pp. 871-876
Author(s):  
G. I. Morozova ◽  
G. M. Barenboim ◽  
G. E. Dobretsov
Keyword(s):  
Fluorescent Probes ◽  
Living Cells

scholarly journals Structure modulation on fluorescent probes for biothiols and the reversible imaging of glutathione in living cells

RSC Advances ◽  
2021 ◽  
Vol 11 (34) ◽  
pp. 21116-21126
Author(s):  
Yu Li ◽  
Li Chen ◽  
Yan Zhu ◽  
Liming Chen ◽  
Xianglin Yu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Living Cells ◽  
Structure Modulation

A reversible fluorescent probe for GSH was obtained through structure modulation, by which the intracellular GSH fluctuation was imaged.

Fast and Selective Two-Stage Ratiometric Fluorescent Probes for Imaging of Glutathione in Living Cells

2017 ◽  
Vol 89 (24) ◽  
pp. 13112-13119 ◽  
Author(s):  
Deyan Gong ◽  
Shi-Chong Han ◽  
Anam Iqbal ◽  
Jing Qian ◽  
Ting Cao ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Living Cells ◽  
Two Stage

Theoretical investigation and design of two-photon fluorescent probes for visualizing β-galactosidase activity in living cells

RSC Advances ◽  
2016 ◽  
Vol 6 (75) ◽  
pp. 70960-70971 ◽  
Author(s):  
Chun Zhang ◽  
Dan Wang ◽  
Li Zhang ◽  
Jing-Fu Guo ◽  
Ai-Min Ren
Keyword(s):  
Theoretical Investigation ◽  
Fluorescent Probes ◽  
Living Cells ◽  
Galactosidase Activity ◽  
Two Photon ◽  
Bio Imaging

The two-photon fluorescent probes show dual signal for β-gal bio-imaging.

Ratiometric fluorescent probes with a self-immolative spacer for real-time detection of β-galactosidase and imaging in living cells

2018 ◽  
Vol 1033 ◽  
pp. 193-198 ◽  
Author(s):  
Xiangzhu Chen ◽  
Xiaodong Ma ◽  
Yuanyuan Zhang ◽  
Gui Gao ◽  
Jingjing Liu ◽  
...  
Keyword(s):  
Real Time ◽  
Fluorescent Probes ◽  
Living Cells ◽  
Real Time Detection

scholarly journals A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Qixin Chen ◽  
Hongbao Fang ◽  
Xintian Shao ◽  
Zhiqi Tian ◽  
Shanshan Geng ◽  
...  
Keyword(s):  
Fluorescence Intensity ◽  
Fluorescent Probes ◽  
Living Cells ◽  
Molecular Probe ◽  
Live Cells ◽  
Blue Fluorescence ◽  
Red Fluorescence ◽  
Dynamic Tracking ◽  
A Cell

AbstractMitochondria–lysosome interactions are essential for maintaining intracellular homeostasis. Although various fluorescent probes have been developed to visualize such interactions, they remain unable to label mitochondria and lysosomes simultaneously and dynamically track their interaction. Here, we introduce a cell-permeable, biocompatible, viscosity-responsive, small organic molecular probe, Coupa, to monitor the interaction of mitochondria and lysosomes in living cells. Through a functional fluorescence conversion, Coupa can simultaneously label mitochondria with blue fluorescence and lysosomes with red fluorescence, and the correlation between the red–blue fluorescence intensity indicates the progress of mitochondria–lysosome interplay during mitophagy. Moreover, because its fluorescence is sensitive to viscosity, Coupa allowed us to precisely localize sites of mitochondria–lysosome contact and reveal increases in local viscosity on mitochondria associated with mitochondria–lysosome contact. Thus, our probe represents an attractive tool for the localization and dynamic tracking of functional mitochondria–lysosome interactions in living cells.

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