Choline esters of N-substituted amino acids: Synthesis and some biological properties

1984 ◽  
Vol 18 (5) ◽  
pp. 312-318
Author(s):  
V. O. Topuzyan ◽  
D. A. Gerasimyan ◽  
A. S. Édilyan ◽  
Yu. Z. Ter-Zakharyan ◽  
R. V. Paronikyan ◽  
...  
Keyword(s):  
Amino Acids ◽  
Biological Properties ◽  
Choline Esters

ChemInform Abstract: SYNTHESIS AND BIOLOGICAL PROPERTIES OF CHOLINE ESTERS OF AMINO ACIDS

1983 ◽  
Vol 14 (28) ◽  
Author(s):  
V. O. TOPUZYAN ◽  
D. A. GERASIMYAN ◽  
A. L. BAGDASARYAN ◽  
O. L. MNDZHOYAN
Keyword(s):  
Amino Acids ◽  
Biological Properties ◽  
Choline Esters

ChemInform Abstract: CHOLINE ESTERS OF N-SUBSTITUTED AMINO ACIDS: SYNTHESIS AND SEVERAL BIOLOGICAL PROPERTIES

1985 ◽  
Vol 16 (1) ◽  
Author(s):  
V. O. TOPUZYAN ◽  
D. A. GERASIYMYAN ◽  
A. S. EDILYAN ◽  
YU. Z. TER-ZAKHARYAN ◽  
R. V. PARONIKYAN ◽  
...  
Keyword(s):  
Amino Acids ◽  
Biological Properties ◽  
Choline Esters

Synthesis and biological properties of choline esters of amino acids

1983 ◽  
Vol 17 (2) ◽  
pp. 87-91
Author(s):  
V. O. Topuzyan ◽  
D. A. Gerasimyan ◽  
A. L. Bagdasaryan ◽  
O. L. Mndzhoyan
Keyword(s):  
Amino Acids ◽  
Biological Properties ◽  
Choline Esters

Bio-organometallic Peptide Conjugates: Recent Advances in Their Synthesis and Prospects for Biomedical Application

2020 ◽  
Vol 24 (21) ◽  
pp. 2508-2523
Author(s):  
Johana Gómez ◽  
Diego Sierra ◽  
Constanza Cárdenas ◽  
Fanny Guzmán
Keyword(s):  
Amino Acids ◽  
Biomedical Application ◽  
Structural Diversity ◽  
Biological Properties ◽  
Therapeutic Agents ◽  
Organometallic Complexes ◽  
Chemical Behavior ◽  
Metal Compounds ◽  
Bioorganometallic Chemistry ◽  
Pharmacological Control

One area of organometallic chemistry that has attracted great interest in recent years is the syntheses, characterization and study of organometallic complexes conjugated to biomolecules with different steric and electronic properties as potential therapeutic agents against cancer and malaria, as antibiotics and as radiopharmaceuticals. This minireview focuses on the unique structural diversity that has recently been discovered in α- amino acids and the reactions of metallocene complexes with peptides having different chemical behavior and potential medical applications. Replacing α-amino acids with metallocene fragments is an effective way of selectively influencing the physicochemical, structural, electrochemical and biological properties of the peptides. Consequently, research in the field of bioorganometallic chemistry offers the opportunity to develop bioactive metal compounds as an innovative and promising approach in the search for pharmacological control of different diseases.

Choline esters of N-substituted amino acids. IX. Synthesis and cholinergic properties of β-dimethylaminoethyl esters of N-substituted amino acids

1997 ◽  
Vol 31 (1) ◽  
pp. 23-26
Author(s):  
V. O. Topuzyan ◽  
G. Yu. Khachvakyan ◽  
L. V. Shakhbazyan ◽  
D. A. Gerasimyan
Keyword(s):  
Amino Acids ◽  
Choline Esters

CHEMICAL AND BIOLOGICAL PROPERTIES OF CULTURE FILTRATES OF WESTIELLOPSIS PROLIFICA AND CHAETOPHORA ATTENUATA

1996 ◽  
Vol 44 (1) ◽  
pp. 43-48 ◽  
Author(s):  
S.C. Agrawal ◽  
U.K. Sharma
Keyword(s):  
Amino Acids ◽  
Aspartic Acid ◽  
Free Amino ◽  
Biological Properties ◽  
Total Chlorophyll ◽  
Total Chlorophyll Content ◽  
Westiellopsis Prolifica ◽  
Total Free Amino Acids ◽  
Zoospore Formation ◽  
Growth And Reproduction

Westiellopsis prolifica Janet and Chaetophora attenuata Hazen cultures released sugars (glucose, fructose, and sucrose), organic acids (oxaloacetic acid and oxalic acid), amino acids, and protein. W. prolifica cultures released the amino acids glycine, serine, cystine, glutamic acid, aspartic acid, and α-alanine, while C. attenuata cultures released glycine, serine, aspartic acid, and α-alanine. W. prolifica and C. attenuata cultures of all ages released more extracellular protein than total free amino acids. Cultures of C. attenuata released more protein than cultures of the same age of W. prolifica. The filtrates from old cultures of W. prolifica and C. attenuata decreased the total chlorophyll content of all algae tested, totally suppressed conjugation in Spirogyra decimino and zoospore formation in C. attenuata, and drastically decreased spore germination in W. prolifica, thus producing stressful conditions affecting the growth and reproduction of these and other algae.

Cyclopentadienyl-Based Amino Acids (Cp-aa) As Phenylalanine Analogues for Tumor Targeting: Syntheses and Biological Properties of [(Cp-aa)M(CO)3](M = Mn, Re,99mTc)

2012 ◽  
Vol 31 (19) ◽  
pp. 6880-6886 ◽  
Author(s):  
Samer Sulieman ◽  
Daniel Can ◽  
John Mertens ◽  
Harmel W. Peindy N’Dongo ◽  
Yu Liu ◽  
...  
Keyword(s):  
Amino Acids ◽  
Tumor Targeting ◽  
Biological Properties
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