Synthesis and antiviral activity of nitrogen-containing adamantane derivatives

1989 ◽  
Vol 23 (4) ◽  
pp. 304-307 ◽  
Author(s):  
Yu. N. Klimochkin ◽  
I. K. Moiseev ◽  
E. I. Boreko ◽  
G. V. Vladyko ◽  
L. V. Korobchenko
Keyword(s):  
Antiviral Activity ◽  
Adamantane Derivatives

ChemInform Abstract: ADAMANTANE DERIVATIVES. IV. SYNTHESIS AND ANTIVIRAL ACTIVITY OF SOME ADAMANTYL-CONTAINING AMIDES

1983 ◽  
Vol 14 (11) ◽  
Author(s):  
V. M. PLAKHOTINIK ◽  
V. YU. KOVTUN ◽  
N. A. LEONTVEVA ◽  
I. G. PETROVA ◽  
N. L. PUSHKARSKAYA ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Adamantane Derivatives

Antiproliferative and Antiviral Activity of Three Libraries of Adamantane Derivatives

2014 ◽  
Vol 347 (5) ◽  
pp. 334-340 ◽  
Author(s):  
Nikola Basarić ◽  
Margareta Sohora ◽  
Nikola Cindro ◽  
Kata Mlinarić-Majerski ◽  
Erik De Clercq ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Adamantane Derivatives

Synthesis and biological activity of adamantane derivatives. III. Antiviral activity of l-(4'-aminophenyl)adamantane derivatives

1976 ◽  
Vol 10 (5) ◽  
pp. 602-605
Author(s):  
G. I. Danilenko ◽  
V. I. Votyakov ◽  
O. T. Andreeva ◽  
M. M. Timofeeva ◽  
M. N. Shashikhina ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antiviral Activity ◽  
Adamantane Derivatives

ChemInform Abstract: Sulfur-Containing Adamantane Derivatives: Synthesis and Antiviral Activity.

ChemInform ◽  
2010 ◽  
Vol 23 (36) ◽  
pp. no-no
Author(s):  
YU. N. KLIMOCHKIN ◽  
I. K. MOISEYEV ◽  
O. V. ABRAMOV ◽  
G. V. VLADYKO ◽  
L. V. KOROBCHENKO ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Adamantane Derivatives ◽  
Sulfur Containing

scholarly journals Quantitative structure-activity relationship modelling of influenza M2 ion channels inhibitors

2021 ◽  
pp. 36-36
Author(s):  
Ivanka Stankova ◽  
Radoslav Chayrov ◽  
Michaela Schmidtke ◽  
Dancho Danalev ◽  
Liudmila Ognichenko ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Antiviral Activity ◽  
Quantitative Structure Activity Relationship ◽  
Adamantane Derivatives ◽  
Amino Acid Residues ◽  
Qsar Analysis ◽  
Chemical Structures ◽  
Low Cytotoxicity

A series of adamantane derivatives (rimantadine and amantadine) incorporating amino-acid residues are investigated by simplex representation of molecular structure (SiRMS) approach in order to found correlation between chemical structures of investigated compounds and obtained data for antiviral activity and cytotoxicity. The obtained data from QSAR analysis show that adamantane derivatives containing amino acids with short aliphatic non-polar residues in the lateral chain will have good antiviral activity against tested virus A/H3N2, strain Hong Kong/68 with low cytotoxicity. QSAR experiments and in vitro data show also good correlation and reveal that modified adamantine derivatives including guanidated in the lateral chain amino acid and ?-amino acids as substituents have lower or do not show any activity.

Synthesis and antiviral activity of new adamantane derivatives

2012 ◽  
Vol 45 (10) ◽  
pp. 588-592 ◽  
Author(s):  
I. K. Moiseev ◽  
S. A. Kon’kov ◽  
K. A. Ovchinnikov ◽  
N. M. Kilyaeva ◽  
K. M. Bormasheva ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Adamantane Derivatives

ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF ADAMANTANE DERIVATIVES. VII. ANTIVIRAL ACTIVITY OF P-ADAMANTYLANILINE HALO DERIVATIVES

1977 ◽  
Vol 8 (36) ◽  
pp. no-no
Author(s):  
G. I. DANILENKO ◽  
V. I. VOTYAKOV ◽  
O. T. ANDREEVA ◽  
I. V. BRUSKOVA ◽  
E. I. DIKOLENKO ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antiviral Activity ◽  
Adamantane Derivatives

scholarly journals Stereoselective synthesis of novel adamantane derivatives with high potency against rimantadine-resistant influenza A virus strains

2017 ◽  
Vol 15 (15) ◽  
pp. 3152-3157 ◽  
Author(s):  
Nikolai Yu. Kuznetsov ◽  
Rabdan M. Tikhov ◽  
Ivan A. Godovikov ◽  
Michael G. Medvedev ◽  
Konstantin A. Lyssenko ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Influenza A Virus ◽  
Influenza A ◽  
Stereoselective Synthesis ◽  
Adamantane Derivatives ◽  
High Potency ◽  
Virus Strains

A series of (R)- and (S)-isomers of new adamantane-substituted heterocycles were synthesized and tested for antiviral activity.

Adamantane derivatives IV. Synthesis and antiviral activity of some amides containing the adamantyl group

1982 ◽  
Vol 16 (9) ◽  
pp. 660-664
Author(s):  
V. M. Plakhotnik ◽  
V. Yu. Kovtun ◽  
N. A. Leon'teva ◽  
I. G. Petrova ◽  
N. L. Lushkarskaya ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Adamantane Derivatives
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