Lipid protein interactions in mitochondria. VIII. Effect of general anesthetics on the mobility of spin labels in lipid vesticles and mitochondrial membranes

1979 ◽  
Vol 11 (1-2) ◽  
pp. 17-32 ◽  
Author(s):  
Laura Mazzanti ◽  
Giovanna Curatola ◽  
Giovanna Zolese ◽  
Enrico Bertoli ◽  
Giorgio Lenaz
Keyword(s):  
Protein Interactions ◽  
Spin Labels ◽  
General Anesthetics ◽  
Mitochondrial Membranes ◽  
Lipid Protein Interactions

scholarly journals Lipid-protein interactions in mitochondrial membranes from bivalve mollusks: molecular strategies in different species

2019 ◽  
Vol 227 ◽  
pp. 12-20 ◽  
Author(s):  
Rosamaria Fiorini ◽  
Vittoria Ventrella ◽  
Fabiana Trombetti ◽  
Micaela Fabbri ◽  
Alessandra Pagliarani ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Bivalve Mollusks ◽  
Mitochondrial Membranes ◽  
Lipid Protein Interactions

scholarly journals Lipid-protein interactions in the structure of mitochondrial membranes

1970 ◽  
Vol 116 (4) ◽  
pp. 27P-28P ◽  
Author(s):  
G Lenaz ◽  
A M Sechi ◽  
G Parenti-Castelli ◽  
L Masotti
Keyword(s):  
Protein Interactions ◽  
Mitochondrial Membranes ◽  
Lipid Protein Interactions

Halogenated general anesthetics in visual photoreceptor membranes as examined by static and dynamic properties of rhodopsin

1993 ◽  
Vol 71 (1-2) ◽  
pp. 57-64 ◽  
Author(s):  
Isabelle Daigle ◽  
Monique Gilbert ◽  
François Boucher
Keyword(s):  
Protein Interactions ◽  
Flash Photolysis ◽  
Dynamic Properties ◽  
Blue Shift ◽  
General Anesthetics ◽  
Environment Change ◽  
Membrane Perturbation ◽  
Rhodopsin Molecule ◽  
Lipid Protein Interactions ◽  
Photoreceptor Membranes

The visual pigment rhodopsin was used as an intrinsic probe to measure the effect of incorporation of enflurane into bovine rod outer segment disk membranes. At moderately low enflurane concentration, we find that, while extrinsic probes show little membrane perturbation, rhodopsin may experience large changes with respect to the native lipid–protein interactions which modulate some of its properties. Enflurane induces a small blue shift in the pigment λmax and a strong inhomogeneity in its photochemical behavior. As a function of enflurane concentration, there appears to be an increasing population of rhodopsin molecules for which the metarhodopsin I → II transition is blocked, while it is accelerated in the remaining population. Under these conditions, electrophoresis and partial membrane solubilization indicate that an increasing amount of rhodopsin does not behave like a free monomeric species. These results are all consistent with a reduction of the membrane order accompanied by lateral aggregation of rhodopsin in the presence of enflurane. By comparison with the perturbation probed by a spin label, the large molecular environment change experienced by the rhodopsin molecule suggests that enflurane may concentrate at the lipid-protein interface.Key words: anesthetics, flash photolysis, lateral aggregation, rhodopsin, visual membranes.

Effects of general anesthetics on lipid protein interactions and atpase activity in mitochondria

1978 ◽  
Vol 27 (24) ◽  
pp. 2835-2844 ◽  
Author(s):  
G. Lenaz ◽  
G. Curatola ◽  
L. Mazzanti ◽  
G. Parenti-Castelli ◽  
E. Bertoli
Keyword(s):  
Atpase Activity ◽  
Protein Interactions ◽  
General Anesthetics ◽  
Lipid Protein Interactions
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