The effect of varying periods of administration and the cessation of administration of sodium diethyldithiocarbamate upon the central nervous system of domestic fowl

1974 ◽  
Vol 28 (3) ◽  
pp. 243-251
Author(s):  
A. R. Rasul ◽  
J. M. Howell
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Domestic Fowl ◽  
Sodium Diethyldithiocarbamate ◽  
The Central Nervous System

Serotoninergic inhibition of LH secretion in the domestic fowl

1986 ◽  
Vol 110 (2) ◽  
pp. 239-244 ◽  
Author(s):  
T. R. Hall ◽  
A. Cheung ◽  
S. Harvey
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Domestic Fowl ◽  
Receptor Agonist ◽  
Time Dependent ◽  
Serotonin Synthesis ◽  
The Central Nervous System ◽  
Lh Secretion

ABSTRACT Immature cockerels were injected with drugs known to affect serotoninergic activity. The receptor agonist quipazine as well as pargyline, an inhibitor of serotonin breakdown, both reduced plasma LH concentrations in a time-dependent fashion. The effect of pargyline was also dose-related. The serotonin precursor, tryptophan, reduced plasma LH levels. Tryptophan and pargyline were as effective in pubertal cockerels as in 3-week-old birds. Responses to quipazine were attenuated by the antagonist, methysergide, although another antagonist, cyproheptadine, also reduced plasma LH levels. Serotonin itself had no effect on plasma LH levels. Parachlorophenylalanine, which blocks serotonin synthesis, had no effect on plasma LH by itself, but attenuated the tryptophan-induced inhibition of LH. These data indicate that serotoninergic mechanisms inhibit secretion of LH in domestic fowl. This mechanism probably operates through the central nervous system. J. Endocr. (1986) 110, 239–244

Effects of Hyperoxia on Lung Utrastructure

1970 ◽  
Vol 28 ◽  
pp. 26-27
Author(s):  
Gladys Harrison
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Light Microscopy ◽  
Oxygen Effects ◽  
Age Dependent ◽  
The Central Nervous System ◽  
The Subject ◽  
Space Age ◽  
Alveolar Septa ◽  
Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

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