Ultrastructural observations on luminal structures of pleomorphic adenoma of parotid and submandibular salivary glands of man

1989 ◽  
Vol 415 (6) ◽  
pp. 559-563 ◽  
Author(s):  
J. D. Harrison ◽  
D. W. Auger
2003 ◽  
Vol 32 (8) ◽  
pp. 499-501 ◽  
Author(s):  
Hui Xu ◽  
Yoshinaka Shimizu ◽  
Takayuki Niki ◽  
Hiroshi Nagasaka ◽  
Hiroshi Kawamura ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Gamilah Al-Qadhi ◽  
Rabab Mubarak

Abstract Objective Khat (Catha edulis Forssk) plant has been widely chewed for its psychostimulatory effects in the African and Arabian Peninsula, particularly in Yemen. Considering the khat leaves are gradually chewed without swallowing, while its active constituents are extracted into saliva, studying the effect of khat on salivary glands is necessary. This work is an extension of the previously published work that studied the effect of khat extract on the rats' submandibular salivary glands in terms of histological and immunohistochemical evaluations. The current research note aimed to better understand this effect on the ultrastructure of submandibular salivary gland cells by using transmission electron microscope. Results Oral administration of khat extract produced degenerative changes in the secretory and ductal cells of rats' submandibular salivary glands. These changes involved irregular boundaries of variable sized-nuclei, dilated RER, cytoplasmic vacuoles as well as swollen and degenerated mitochondria.


1990 ◽  
Vol 69 (8) ◽  
pp. 1494-1499 ◽  
Author(s):  
A. Letić-Gavrilović ◽  
K. Abe

The localizations of chromogranins A, B, and C, neuron-specific enolase (NSE, γγ-type) and non-NSE (αα-type), and different forms of somatostatins were immunocytochemically identified. The localizations were compared with those of epidermal growth factor (EGF) and nerve growth factor (NGF) in the submandibular salivary glands (SMG) of male mice at five to six weeks of age, with use of a variety of antibodies and the peroxidase-antiperoxidase (PAP) and avidin-biotin complex (ABC) detection methods. In the SMG of male mice, the major chromogranin present was chromogranin A, whereas chromogranins B and C were not detected at these ages by either method. Chromogranin Alike immunoreactivity was located in the granular convoluted tubule (GCT) cells of the SMG, whereas non-NSE immunoreactivity was observed throughout the duct system and in some acinar-associated cells. NSE was not detected in any part of the SMG. The distribution of chromogranin A and somatostatins in the GCT cells was similar to that of EGF and NGF. Our results strongly suggest that chromogranin A and somatostatins, but not chromogranin B or C, may be useful as a means of differentiation of the cells in the duct system of the SMG responsible for the production of biologically-active factors.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Geovanni Dantas Cassali ◽  
Angélica Cavalheiro Bertagnolli ◽  
Enio Ferreira ◽  
Karine Araújo Damasceno ◽  
Conrado de Oliveira Gamba ◽  
...  

Mammary mixed tumours are the most frequent neoplasias in female dogs. In humans, mixed tumours are frequently found in the salivary glands and are known as pleomorphic adenomas. In addition to their histomorphologic similarities, mixed tumours and pleomorphic adenomas have the potential to become malignant and give rise to carcinomas in mixed tumours and carcinomas ex-pleomorphic adenoma, respectively. The factors associated with malignant transformation are still poorly known in the case of canine mixed tumours. However, this form of neoplasia tends to be associated with a better prognosis than other malignant histological types. This paper discusses the main features associated with female canine mammary mixed tumours.


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