scholarly journals Growth hormone effect on accumulation of arterial basement membrane-like material studied on rabbit aortic myomedial cell cultures

Diabetologia ◽  
1985 ◽  
Vol 28 (12) ◽  
pp. 922-927 ◽  
Author(s):  
T. Ledet ◽  
L. Heickendorff
Keyword(s):  
Growth Hormone ◽  
Basement Membrane ◽  
Cell Cultures ◽  
Hormone Effect

Lack of growth hormone effect on insulin-associated suppression of insulinlike growth factor binding protein 1 in humans

Diabetes ◽  
1990 ◽  
Vol 39 (10) ◽  
pp. 1251-1256 ◽  
Author(s):  
C. A. Conover ◽  
P. C. Butler ◽  
M. Wang ◽  
R. A. Rizza ◽  
P. D. Lee
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Binding Protein ◽  
Factor Binding ◽  
Insulinlike Growth Factor ◽  
Hormone Effect

Correlation between Immunoreactive Growth Hormone and Prolactin Activity in Human and Simian Pituitary Cell Cultures

1969 ◽  
Vol 132 (2) ◽  
pp. 505-508 ◽  
Author(s):  
I. L. Solomon ◽  
D. B. Grant ◽  
I. M. Burr ◽  
S. L. Kaplan ◽  
M. M. Grumbach
Keyword(s):  
Growth Hormone ◽  
Cell Cultures ◽  
Pituitary Cell

Absence of a growth hormone effect on rat soleus atrophy during a 4-day spaceflight

1993 ◽  
Vol 74 (2) ◽  
pp. 527-531 ◽  
Author(s):  
B. Jiang ◽  
R. R. Roy ◽  
C. Navarro ◽  
V. R. Edgerton
Keyword(s):  
Growth Hormone ◽  
Succinate Dehydrogenase ◽  
Cross Sections ◽  
Fiber Type ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Fast Myosin ◽  
Hormone Effect ◽  
Fast Myosin Heavy Chain

The objectives of the present study were to determine the size and enzyme properties of soleus fibers of rats subjected to a 4-day spaceflight (National Aeronautics and Space Administration, STS-41) and the effects of exogenous growth hormone (GH) on the atrophic response of the muscle. Four groups of rats were studied: 1) control (Con), 2) Con plus GH treated (Con + GH), 3) flight (Fl), and 4) F1 plus GH treated (Fl + GH). Cross-sectional area and the activities of succinate dehydrogenase and myofibrillar adenosinetriphosphatase (ATPase) were determined in fibers identified in frozen serial cross sections. Fibers were categorized immunohistochemically as slow, fast, or slow-fast on the basis of their reaction with slow and fast myosin heavy-chain (MHC) monoclonal antibodies. Fibers also were categorized as light or dark on the basis of their staining for ATPase at pH 8.6. After the 4-day flight, mean body weight was significantly decreased compared with control. The absolute and relative (muscle wt/body wt) soleus weights were significantly smaller in the Fl and Fl + GH rats compared with their respective ground-based controls. In both flight groups, the cross-sectional area of the light ATPase fibers was significantly smaller (approximately 30%) than control. Three of 11 flight rats had a higher proportion of fibers expressing both slow and fast MHCs than expected on the basis of the fiber type distribution in the 11 control rats. Mean fiber succinate dehydrogenase and ATPase activities were similar among the four groups.(ABSTRACT TRUNCATED AT 250 WORDS)

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