Computed tomography of the brain in the diagnosis of and prognosis in normal pressure hydrocephalus

1989 ◽  
Vol 31 (2) ◽  
pp. 160-165 ◽  
Author(s):  
C. Wikkels� ◽  
H. Andersson ◽  
C. Blomstrand ◽  
M. Matousek ◽  
P. Svendsen
Keyword(s):  
Computed Tomography ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
The Brain

Computed Tomography of the Brain in the Diagnosis of and Prognosis in Normal Pressure Hydrocephalus

1991 ◽  
pp. 119-120
Author(s):  
Carsten Wikkelsø ◽  
Hugo Andersson ◽  
Christian Blomstrand ◽  
Milos Matousek ◽  
Pål Svendsen
Keyword(s):  
Computed Tomography ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
The Brain

scholarly journals Pre-and postoperative cerebral blood flow changes in patients with idiopathic normal pressure hydrocephalus measured by computed tomography (CT)-perfusion

2016 ◽  
Vol 36 (10) ◽  
pp. 1755-1766 ◽  
Author(s):  
Doerthe Ziegelitz ◽  
Jonathan Arvidsson ◽  
Per Hellström ◽  
Mats Tullberg ◽  
Carsten Wikkelsø ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Lentiform Nucleus ◽  
Spatial Coverage ◽  
Potential Biomarker ◽  
Subcortical Regions

In idiopathic normal pressure hydrocephalus (iNPH), the cerebral blood flow (CBF) is of pathophysiological interest and a potential biomarker. Computed tomography perfusion (CTP), an established technique with high spatial resolution and quantitative measurements, has not yet been used in the iNPH context. If CTP were sensitive to the CBF levels and changes in iNPH, this technique might provide diagnostic and prognostic absolute perfusion thresholds. The aim of this work was to determine the applicability of CTP to iNPH. CBF measurements of 18 patients pre- and 17 three months postoperatively, and six healthy individuals (HI) were evaluated in 12 cortical and subcortical regions of interest. Correlations between CBF and symptomatology were analyzed in shunt-responders. Compared to HI, the preoperative CBF in iNPH was significantly reduced in normal appearing and periventricular white matter (PVWM), the lentiform nucleus and the global parenchyma. No CBF differences were shown between responders and non-responders. In responders, the CBF recovered postoperatively by 2.5–32% to approximately the level of HI, but remained significantly decreased in the PVWM of non-responders. The pre- and postoperative CBF of cortical and subcortical regions correlated with the intensity of symptoms. In spite of limited spatial coverage, CTP can measure CBF changes in iNPH.

In vivo viscoelastic properties of the brain in normal pressure hydrocephalus

2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
Kaspar-Josche Streitberger ◽  
Edzard Wiener ◽  
Jan Hoffmann ◽  
Florian Baptist Freimann ◽  
Dieter Klatt ◽  
...  
Keyword(s):  
Normal Pressure Hydrocephalus ◽  
Viscoelastic Properties ◽  
Normal Pressure ◽  
The Brain

Cerebral cysticercosis with aqueductal obstruction

1980 ◽  
Vol 53 (2) ◽  
pp. 252-255 ◽  
Author(s):  
Tung Pui Poon ◽  
Edward J. Arida ◽  
Wolodymyr P. Tyschenko
Keyword(s):  
Intracranial Hypertension ◽  
Brain Stem ◽  
Normal Pressure Hydrocephalus ◽  
Signs And Symptoms ◽  
Normal Pressure ◽  
Content Type ◽  
Neurological Signs ◽  
Cerebral Cysticercosis ◽  
The Brain ◽  
Fine Print

✓ The authors report a case of cerebral cysticercosis which presented with generalized nonspecific neurological signs and symptoms attributed to acute aqueductal obstruction, with concomitant intracranial hypertension. These were characteristic intracranial calcifications along with angiographically demonstrated signs of hydrocephalus. Contrast encephalography clearly demonstrated aqueductal obstruction. Pathologically, the aqueductal obstruction was shown to be due to parasitic invasion of the brain stem with compression of the aqueduct. The presence of typical intracranial calcification in conjunction with either obstructive or normal-pressure hydrocephalus should alert the observer to the possibility of cerebral cysticercosis.

Modelling Normal Pressure Hydrocephalus as a ‘Two-Hit’ Disease Using Multiple-Network Poroelastic Theory

2010 ◽  
Author(s):  
Brett Tully ◽  
Yiannis Ventikos
Keyword(s):  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
Brain Parenchyma ◽  
Strongly Correlated ◽  
Clinical Markers ◽  
Cerebral Diseases ◽  
Spatio Temporal ◽  
Multiple Network ◽  
Poroelastic Theory ◽  
The Brain

The evolution of many cerebral diseases such as Alzheimer’s and Parkinson’s Disease, Hydrocephalus, Cerebral Oedema, Stroke, and Tumour are strongly correlated to a change in the transport properties of fluid in the brain. This research proposes a novel application of Multiple-Network Poroelastic Theory (MPET) to investigate cerebral hydrodynamics through a detailed investigation of multiscalar, spatio-temporal transport of fluid between the cerebral blood, cerebrospinal fluid (CSF) and brain parenchyma. Specifically, MPET is used to interrogate the clinical markers of Normal Pressure Hydrocephalus (NPH).

Sign in / Sign up

Export Citation Format

Share Document