The influence of photoperiod and melatonin on testis size, body weight, and pelage colour in the Djungarian hamster (Phodopus sungorus)

1973 ◽  
Vol 85 (3) ◽  
pp. 267-282 ◽  
Author(s):  
Klaus Hoffmann
Keyword(s):  
Body Weight ◽  
Phodopus Sungorus ◽  
Testis Size ◽  
Djungarian Hamster

scholarly journals Photoperiodic and Diurnal Regulation of WNT Signaling in the Arcuate Nucleus of the Female Djungarian Hamster, Phodopus sungorus

Endocrinology ◽  
2015 ◽  
Vol 157 (2) ◽  
pp. 799-809 ◽  
Author(s):  
Alisa Boucsein ◽  
Jonas Benzler ◽  
Cindy Hempp ◽  
Sigrid Stöhr ◽  
Gisela Helfer ◽  
...  
Keyword(s):  
Body Weight ◽  
Wnt Signaling ◽  
Wnt Pathway ◽  
Arcuate Nucleus ◽  
Integration Site ◽  
Phodopus Sungorus ◽  
Weight Regulation ◽  
Body Weight Regulation ◽  
Djungarian Hamster ◽  
Diurnal Regulation

Abstract The WNT pathway was shown to play an important role in the adult central nervous system. We previously identified the WNT pathway as a novel integration site of the adipokine leptin in mediating its neuroendocrine control of metabolism in obese mice. Here we investigated the implication of WNT signaling in seasonal body weight regulation exhibited by the Djungarian hamster (Phodopus sungorus), a seasonal mammal that exhibits profound annual changes in leptin sensitivity. We furthermore investigated whether crucial components of the WNT pathway are regulated in a diurnal manner. Gene expression of key components of the WNT pathway in the hypothalamus of hamsters acclimated to either long day (LD) or short day (SD) photoperiod was analyzed by in situ hybridization. We detected elevated expression of the genes WNT-4, Axin-2, Cyclin-D1, and SFRP-2, in the hypothalamic arcuate nucleus, a key energy balance integration site, during LD compared with SD as well as a diurnal regulation of Axin-2, Cyclin-D1, and DKK-3. Investigating the effect of photoperiod as well as leptin on the activation (phosphorylation) of the WNT coreceptor LRP-6-(Ser1490) by immunohistochemistry, we found elevated activity in the arcuate nucleus during LD relative to SD as well as after leptin treatment (2 mg/kg body weight). These findings indicate that differential WNT signaling may be associated with seasonal body weight regulation and is partially regulated in a diurnal manner in the adult brain. Furthermore, they suggest that this pathway plays a key role in the neuroendocrine regulation of body weight and integration of the leptin signal.

Photoperiodically induced changes in the epididymis of the Djungarian hamster, Phodopus sungorus

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S179-S180 ◽  
Author(s):  
M. BERGMANN ◽  
C. LEETZ ◽  
J. SCHINDELMEISER ◽  
E.M. KINDERMANN ◽  
M. KUTZNER ◽  
...  
Keyword(s):  
Phodopus Sungorus ◽  
Djungarian Hamster ◽  
Induced Changes

Sex differences in the distribution of adipose tissue in the Djungarian hamster Phodopus sungorus

1987 ◽  
Vol 7 (12) ◽  
pp. 1325-1328 ◽  
Author(s):  
Caroline M. Pond ◽  
Dawn Sadler ◽  
Christine A. Mattacks
Keyword(s):  
Sex Differences ◽  
Adipose Tissue ◽  
Phodopus Sungorus ◽  
Djungarian Hamster
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