Effects of arginine phosphate and octopine on glycolytic enzyme activities fromSepia officinalis mantle muscle

1981 ◽  
Vol 142 (4) ◽  
pp. 501-507 ◽  
Author(s):  
Kenneth B. Storey
Keyword(s):  
Enzyme Activities ◽  
Glycolytic Enzyme

Comparison between Glycolytic Enzyme Activities in Benign and Malignant Breast Tumors

1985 ◽  
pp. 839-842
Author(s):  
J. OGLOBINE ◽  
F. SPYRATOS ◽  
R. LIDEREAU ◽  
C. BRAULT ◽  
A. DESPLACES
Keyword(s):  
Enzyme Activities ◽  
Breast Tumors ◽  
Glycolytic Enzyme ◽  
Malignant Breast

Effect of hypoxemia on tissue glycogen content and glycolytic enzyme activities in fetal sheep

1997 ◽  
Vol 272 (1) ◽  
pp. R103-R110 ◽  
Author(s):  
L. L. Stratford ◽  
S. B. Hooper
Keyword(s):  
Enzyme Activities ◽  
Glycogen Content ◽  
Glycogen Synthase ◽  
Fetal Liver ◽  
Glycolytic Enzyme ◽  
Hepatic Glycogen ◽  
Fetal Sheep ◽  
Total Enzyme Activity ◽  
Pregnant Sheep ◽  
Glycogen Stores

We have tested the hypothesis that prolonged fetal hypoxemia causes a reduction in glycogenolytic enzyme activities and/or a depletion of fetal glycogen stores. We compared the effects of short (4 h) and prolonged (24 h) periods of reduced maternal uterine blood flow (RUBF) on glycogen content and on the activities of glucose-6-phosphatase (G-6-Pase), glycogen phosphorylase (GPase), and glycogen synthase (GSase) in selected fetal tissues. RUBF was reduced in 10 pregnant sheep at 135 days of gestation (term approximately 146 days) for either 4 h (n = 5) or 24 h (n = 5); 5 other fetuses were used as controls. During RUBF, fetal SaC2 was decreased from 61.6 +/- 3.9 to 22.0 +/- 1.4% at 4 h and to 26.7 +/- 1.2% at 24 h. Hepatic glycogen content was significantly reduced at 4 h of RUBF, but was not reduced further at 24 h. Fetal liver GPase (active and total enzyme activity) and G-6-Pase activities were reduced at 4 h of RUBF but tended to return toward control values at 24 h. Similarly, hepatic GSase activity tended to decrease at 4 h of RUBF, although the reduction was not quite significant (P = 0.08). We conclude that RUBF causes a reduction of fetal glycogen stores and a reduction in G-6-Pase and GPase activity at 4 h. Fetal tissue glycogen contents were not reduced further at 24 h, compared with 4 h of RUBF, which indicates that fetal glycogenolysis is reduced during this time, probably because of the inhibition of GPase and G-6-Pase. It is not known why the activities of these enzymes are reduced during prolonged RUBF, when circulating epinephrine and norepinephrine concentrations are high.

Ultrastructural and enzymatic development of fetal guinea pig heart

1982 ◽  
Vol 243 (1) ◽  
pp. H87-H93 ◽  
Author(s):  
T. P. Rolph ◽  
C. T. Jones ◽  
D. Parry
Keyword(s):  
Guinea Pig ◽  
Atpase Activity ◽  
Enzyme Activities ◽  
Citric Acid Cycle ◽  
Acid Metabolism ◽  
Fetal Heart ◽  
Glycolytic Enzyme ◽  
Guinea Pig Heart ◽  
Threefold Increase ◽  
Phosphofructokinase Activity

The activities of some enzymes of glycolysis, the citric acid cycle, and amino acid metabolism have been measured in the fetal guinea pig heart over the last third of gestation and correlated with heart ultrastructural development. There is little change in glycolytic enzyme activity except for a two- to threefold increase in phosphofructokinase activity. Mitochondrial content and enzyme activities are low in the early fetal heart, and, although content is similar in the late fetus and adult, enzyme activities increase twofold postnatally, indicating fetal heart mitochondria are incompletely developed. The activities of aspartate and particularly alanine aminotransferase are low in the fetal heart. Over the last third of gestation the myofibrillar content of the fetal myocyte increases twofold to the adult value by term. Associated with this is a fourfold rise in myofibrillar and sarcoplasmic reticulum Ca2+-ATPase activity. Na+-K+-ATPase activity is similar in the late fetal and adult heart but one-third lower in the early fetal heart.

Effects of the β2-agonist clenbuterol on respiratory and limb muscles of weaning rats

2001 ◽  
Vol 280 (3) ◽  
pp. R862-R869 ◽  
Author(s):  
B. Polla ◽  
V. Cappelli ◽  
F. Morello ◽  
M. A. Pellegrino ◽  
F. Boschi ◽  
...  
Keyword(s):  
Enzyme Activities ◽  
Fiber Type ◽  
Muscle Growth ◽  
Chronic Administration ◽  
Growth Stimulation ◽  
Glycolytic Enzyme ◽  
Myosin Heavy Chain Isoforms ◽  
Adult Rats ◽  
Type Transformation ◽  
Contractile Performance

The aim of this study was to analyze the effects of chronic administration of the β2-agonist clenbuterol (1.5 mg · kg−1 · day−1 for 4 wk in the drinking water) on respiratory (diaphragm and parasternal intercostal) and hindlimb (tibialis and soleus) muscles in young rats during postnatal development (21 to 49 postnatal days). The treatment resulted in very little stimulation of muscle growth. Significant slow-to-fast transitions in the expression of myosin heavy chain isoforms and significant increases in the myofibrillar ATPase activity were found in the diaphragm and soleus, whereas tibialis anterior and intercostal muscles did not show any significant fiber-type alteration. Decrease of oxidative enzyme activities and increase of glycolytic enzyme activities were also observed. It is concluded that whereas the growth stimulation is age dependent and only detectable in adult rats, the fiber-type transformation is also present in weaning rats and particularly evident in the soleus and diaphragm. The fiber-type transformation caused by clenbuterol might lead to an enhancement of contractile performance and also to a reduced resistance to fatigue.

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