Experimental study on pathogenesis of the fetal brain damage by acute carbon monoxide intoxication of the pregnant mother

1986 ◽  
Vol 69 (3-4) ◽  
pp. 244-252 ◽  
Author(s):  
R. Okeda ◽  
T. Matsuo ◽  
T. Kuroiwa ◽  
T. Tajima ◽  
H. Takahashi
Keyword(s):  
Experimental Study ◽  
Carbon Monoxide ◽  
Brain Damage ◽  
Fetal Brain ◽  
Pregnant Mother ◽  
Carbon Monoxide Intoxication

An experimental study of the pathogenesis of Grinker's myelinopathy in carbon monoxide intoxication

1983 ◽  
Vol 59 (3) ◽  
pp. 200-206 ◽  
Author(s):  
R. Okeda ◽  
S. -Y. Song ◽  
N. Funta ◽  
F. Higashino
Keyword(s):  
Experimental Study ◽  
Carbon Monoxide ◽  
Carbon Monoxide Intoxication

Study of Carbon Monoxide Intoxication in Fire Victimis

2018 ◽  
Vol 68 (12) ◽  
pp. 2932-2935
Author(s):  
Sofia David ◽  
Anton Knieling ◽  
Calin Scripcaru ◽  
Madalina Diac ◽  
Ion Sandu ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Poisoning ◽  
Inverse Correlation ◽  
Blood Samples ◽  
Mortality And Morbidity ◽  
Carbon Monoxide Intoxication ◽  
Gas Poisoning ◽  
The World ◽  
Fire Victims ◽  
In Fire

Carbon monoxide poisoning is the leading cause of mortality and morbidity of toxic origin in the world. Its insidious and polymorphic symptomatology makes it difficult to diagnose. It occurs accidentally, because of non-supervised domestic fires, or in fire victims. In fire victims, in particular, the differential diagnosis between carbon monoxide gas poisoning, inhalation of other toxic products of combustion like cyanide, oxygen deprivation, thermal burns and shock due to burns as a cause of death is not an easy task. The authors examined 107 fire victims that were autopsied at the Forensic Medicine from Iasi, Romania, in the last 10 years (2007-2016). Most cases were males (69.16%), young (0-9 years) or older than 60 with a burned surface of 91-100% in 68.22% of cases. Blood samples from the cadavers were collected in all cases in order to analyse carboxyhaemoglobin concentration and haemolysis. Toxicological analysis revealed a carboxyhaemoglobin level of maximum 95% but the majority of cases (70.72%) had a concentration inferior to 50%. An inverse correlation was identified between carboxyhaemoglobin concentration and haemolysis, an indicator of heat dissociation. Our study proves that many fire victims may die because of carbon monoxide intoxication prior to the extent of burns at a lethal potential.

scholarly journals The History of Carbon Monoxide Intoxication

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 400
Author(s):  
Ioannis-Fivos Megas ◽  
Justus P. Beier ◽  
Gerrit Grieb
Keyword(s):  
Carbon Monoxide ◽  
Middle Ages ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Diagnosis And Treatment ◽  
Carbon Monoxide Intoxication ◽  
History Of ◽  
The Middle Ages

Intoxication with carbon monoxide in organisms needing oxygen has probably existed on Earth as long as fire and its smoke. What was observed in antiquity and the Middle Ages, and usually ended fatally, was first successfully treated in the last century. Since then, diagnostics and treatments have undergone exciting developments, in particular specific treatments such as hyperbaric oxygen therapy. In this review, different historic aspects of the etiology, diagnosis and treatment of carbon monoxide intoxication are described and discussed.

scholarly journals Cognitive Severity-Specific Neuronal Degenerative Network in Charcoal Burning Suicide-Related Carbon Monoxide Intoxication

Medicine ◽  
2015 ◽  
Vol 94 (19) ◽  
pp. e783 ◽  
Author(s):  
Nai-Ching Chen ◽  
Chi-Wei Huang ◽  
Shu-Hua Huang ◽  
Wen-Neng Chang ◽  
Ya-Ting Chang ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Charcoal Burning ◽  
Carbon Monoxide Intoxication

An experimental study of the influences of tobacco smoke on fertility and reproduction

1999 ◽  
Vol 18 (4) ◽  
pp. 272-278 ◽  
Author(s):  
Ewa Florek ◽  
Andrzej Marszalek
Keyword(s):  
Experimental Study ◽  
Carbon Monoxide ◽  
Tobacco Smoke ◽  
Female Rats ◽  
Dose Effect ◽  
Smoke Inhalation ◽  
Initial Number ◽  
Cigarette Brand ◽  
Duration Of Pregnancy ◽  
Parent Generation

1 The aim of this study was to evaluate the toxicological influence of tobacco smoke on fertility and reproduction of Wistar female rats. The influence of tobacco smoke from the Polish ‘Popularne’ cigarette brand was studied. The experiment was conducted on three generations of animals, each generation having two litters. The initial number of animals of the parent generation FO was 192 (128 females and 64 males). Animals were passively exposed to tobacco smoke in three different concentrations based on the content of carbon monoxide (500, 1000 and 1500 mg of CO per cubic meter of air). Animals were exposed to tobacco smoke for 6 h a day, 5 days a week, during 11 weeks. 2 The analysis of indices of mating and fertility revealed the decrease in those indices with animals exposed to tobacco smoke. We also observed an increased number of mothers breading among animals exposed to tobacco smoke. In animals exposed to tobacco smoke, the dose-effect or dose-response dependencies for mating, fertility and delivery indices were found. There was no influence of tobacco smoke on the duration of pregnancy. 3 Tobacco smoke inhalation caused increased levels of carboxyhaemoglobin. 4 Tobacco smoke did not change the duration of pregnancy in rats.

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