Non-immunological release of histamine from rat mast cells elicited by antineoplastic agents

1992 ◽  
Vol 29 (6) ◽  
pp. 495-498 ◽  
Author(s):  
L. M. Botana ◽  
E. Arnaez ◽  
M. R. Vieytes ◽  
A. Alfonso ◽  
M. J. Bujan ◽  
...  
Keyword(s):  
Mast Cells ◽  
Antineoplastic Agents ◽  
Rat Mast Cells

Nonimmunological release of histamine from rat mast cells elicited by antineoplastic agents: effect of drug combinations

1992 ◽  
Vol 30 (6) ◽  
pp. 487-490 ◽  
Author(s):  
L. M. Botana ◽  
E. Arnaez ◽  
M. R. Vieytes ◽  
A. Alfonso ◽  
M. C. Louzao
Keyword(s):  
Mast Cells ◽  
Antineoplastic Agents ◽  
Drug Combinations ◽  
Rat Mast Cells

Binding of rat IgE with the subcellular components of normal rat mast cells

1976 ◽  
Vol 13 (4) ◽  
pp. 345-353 ◽  
Author(s):  
Wolfgang König ◽  
Kimishige Ishizaka
Keyword(s):  
Mast Cells ◽  
Normal Rat ◽  
Rat Mast Cells

Expression and function of fibronectin binding integrins on rat mast cells

1995 ◽  
Vol 7 (2) ◽  
pp. 251-258 ◽  
Author(s):  
Masahiko Yasuda ◽  
Yukihito Hasunuma ◽  
Hiroyasu Adachi ◽  
Chiyoko Sekine ◽  
Tamami Sakanishi ◽  
...  
Keyword(s):  
Mast Cells ◽  
Fibronectin Binding ◽  
And Function ◽  
Rat Mast Cells

scholarly journals Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells.

1987 ◽  
Vol 105 (1) ◽  
pp. 191-197 ◽  
Author(s):  
T W Howell ◽  
S Cockcroft ◽  
B D Gomperts
Keyword(s):  
Mast Cells ◽  
Rank Order ◽  
Regulatory Protein ◽  
Metabolic Inhibitors ◽  
Pyrimidine Nucleotides ◽  
Permeabilized Cells ◽  
Streptolysin O ◽  
Gamma S ◽  
Sufficient Stimulus ◽  
Rat Mast Cells

Rat mast cells, pretreated with metabolic inhibitors and permeabilized by streptolysin-O, secrete histamine when provided with Ca2+ (buffered in the micromolar range) and nucleoside triphosphates. We have surveyed the ability of various exogenous nucleotides to support or inhibit secretion. The preferred rank order in support of secretion is ITP greater than XTP greater than GTP much greater than ATP. Pyrimidine nucleotides (UTP and CTP) are without effect. Nucleoside diphosphates included alongside Ca2+ plus ITP inhibit secretion in the order 2'-deoxyGDP greater than GDP greater than o-GDP greater than ADP approximately equal to 2'deoxyADP approximately equal to IDP. Secretion from the metabolically inhibited and permeabilized cells can also be induced by stable analogues of GTP (GTP-gamma-S greater than GppNHp greater than GppCH2p) which synergize with Ca2+ to trigger secretion in the absence of phosphorylating nucleotides. ATP enhances the effective affinity for Ca2+ and GTP analogues in the exocytotic process but does not alter the maximum extent of secretion. The results suggest that the presence of Ca2+ combined with activation of events controlled by a GTP regulatory protein provide a sufficient stimulus to exocytotic secretion from mast cells.

Effect of Kinins and of Kinin-Releasing Enzymes on Rat Mast Cells

1972 ◽  
pp. 317-323 ◽  
Author(s):  
A. M. Rothschild ◽  
M. P. O. Antonio ◽  
J. J. Dias ◽  
A. Castania ◽  
L. C. Neves
Keyword(s):  
Mast Cells ◽  
Rat Mast Cells

The effect of glycoprotein from Candida albicans on isolated rat mast cells

Toxicon ◽  
1974 ◽  
Vol 12 (2) ◽  
pp. 103-106 ◽  
Author(s):  
R. Nosál ◽  
J. Novotný ◽  
D. Sikl
Keyword(s):  
Candida Albicans ◽  
Mast Cells ◽  
Isolated Rat ◽  
Rat Mast Cells

Ouabain-induced enhancement of rat mast cells response

2001 ◽  
Vol 13 (7) ◽  
pp. 515-524 ◽  
Author(s):  
J Lago ◽  
A Alfonso ◽  
M.R Vieytes ◽  
L.M Botana
Keyword(s):  
Mast Cells ◽  
Rat Mast Cells
Sign in / Sign up

Export Citation Format

Share Document