Histochemical studies on the mechanism of action of the hallucinogens d-lysergic acid diethylamide tartrate (LSD-25) and d-2-bromo-lysergic acid tartrate (BOL-148) in rat brain

1963 ◽  
Vol 3 (1) ◽  
pp. 29-39 ◽  
Author(s):  
T. R. Shanthaveerappa ◽  
K. Nandy ◽  
G. H. Bourne
Keyword(s):  
Rat Brain ◽  
Mechanism Of Action ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide

Serotonin Binding to Nerve-Ending Particles of the Rat Brain and Its Inhibition by Lysergic Acid Diethylamide

Science ◽  
1964 ◽  
Vol 144 (3622) ◽  
pp. 1135-1137 ◽  
Author(s):  
R. M. Marchbanks ◽  
F. Rosenblatt ◽  
R. D. O'Brien
Keyword(s):  
Rat Brain ◽  
Nerve Ending ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide

scholarly journals d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology

2016 ◽  
Vol 17 (11) ◽  
pp. 1953 ◽  
Author(s):  
Danilo De Gregorio ◽  
Stefano Comai ◽  
Luca Posa ◽  
Gabriella Gobbi
Keyword(s):  
Mechanism Of Action ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide

Binding of d-Lysergic Acid Diethylamide to Subcellular Fractions from Rat Brain

Nature ◽  
1972 ◽  
Vol 237 (5351) ◽  
pp. 164-166 ◽  
Author(s):  
JOHN T. FARROW ◽  
HELEN VAN VUNAKIS
Keyword(s):  
Rat Brain ◽  
Lysergic Acid ◽  
Subcellular Fractions ◽  
Lysergic Acid Diethylamide

Effect of and Interaction Between Tranquilizers, Serotonin and Lysergic Acid Diethylamide on the Body Temperature of Pigeons

1958 ◽  
Vol 195 (3) ◽  
pp. 751-754 ◽  
Author(s):  
Roger A. Hoffman
Keyword(s):  
Body Temperature ◽  
Mechanism Of Action ◽  
Lysergic Acid ◽  
The Body ◽  
Lysergic Acid Diethylamide ◽  
Induced Hypothermia ◽  
Mutual Antagonism ◽  
Therapeutic Value ◽  
Temperature Responses

The temperature responses of the pigeon to serotonin, reserpine, chlorpromazine and LSD-25 were investigated. It was demonstrated that a rapid hypothermia and depre sioa follow the administration of all compounds except chlorpromazine. Serotonin, reserpine and chlorpromazine were shown to have certain prophylactic and therapeutic value on the LSD-25-induced hypothermia. The data indicate that a mutual antagonism exists in the interaction of these compounds. It is suggested that the mechanism of action of these drugs is quite complex, leading to mixed reactions, depending perhaps on what measurement is being considered.

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