Field stimulation-induced responses of circular smooth muscle from guinea-pig stomach

1983 ◽  
Vol 323 (2) ◽  
pp. 155-161 ◽  
Author(s):  
Brenda Costall ◽  
Robert J. Naylor ◽  
Connie C. W. Tan
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Induced Responses ◽  
Field Stimulation ◽  
Circular Smooth Muscle ◽  
Guinea Pig Stomach

Effects of mucosal removal on guinea-pig airway smooth muscle responsiveness

1986 ◽  
Vol 70 (6) ◽  
pp. 571-575 ◽  
Author(s):  
Christopher Murlas
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Airway Smooth Muscle ◽  
Contractile Response ◽  
Electrical Field Stimulation ◽  
Physiological Salt Solution ◽  
Induced Responses ◽  
Field Stimulation ◽  
Electrical Field ◽  
Airway Mucosa

1. The contractile response to histamine, acetylcholine (ACh), KCl or electrical field stimulation (EFS) was examined in paired tracheal rings (one of each being denuded by mucosal rubbing), which were mounted in muscle chambers filled with a continuously aerated physiological salt solution at 37°C. 2. Removal of the respiratory mucosa increased the sensitivity of airway muscle to ACh, histamine and EFS, but not to KCl. The hypersensitivity of denuded rings to histamine and EFS was greater than to ACh. Atropine reduced the histamine hypersensitivity observed. 3. Pretreating intact preparations with indomethacin augmented their responsiveness to EFS, histamine and ACh. 4. Indomethacin augmentation of histamine- and EFS-induced responses was greater in preparations without epithelium. 5. We conclude that the airway mucosa may be associated with a factor that reduces airway smooth muscle responsiveness to stimulation.

scholarly journals Modification by charybdotoxin and apamin of spontaneous electrical and mechanical activity of the circular smooth muscle of the guinea-pig stomach

1993 ◽  
Vol 109 (3) ◽  
pp. 661-666 ◽  
Author(s):  
Keiko Suzuki ◽  
Kaoru M. Ito ◽  
Yukie Minayoshi ◽  
Hikaru Suzuki ◽  
Masahisa Asano ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Mechanical Activity ◽  
Circular Smooth Muscle ◽  
Guinea Pig Stomach

scholarly journals Effects of cromakalim on the contraction and the membrane potential of the circular smooth muscle of guinea-pig stomach

1992 ◽  
Vol 105 (2) ◽  
pp. 335-340 ◽  
Author(s):  
Katsuaki Ito ◽  
Tomohiro Kanno ◽  
Keiko Suzuki ◽  
Kaoru Masuzawa-Ito ◽  
Tadashi Takewaki ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Membrane Potential ◽  
Guinea Pig ◽  
Circular Smooth Muscle ◽  
Guinea Pig Stomach
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