On the role of the carbon chain length of fatty acids and alcohols for elicitation of epidermal hyperplasia in mouse skin

1961 ◽  
Vol 48 (12) ◽  
pp. 459-460 ◽  
Author(s):  
Paul Holsti
Keyword(s):  
Fatty Acids ◽  
Chain Length ◽  
Mouse Skin ◽  
Carbon Chain ◽  
Carbon Chain Length ◽  
Epidermal Hyperplasia ◽  
Fatty Acids And Alcohols

scholarly journals SELECTIVITY OF CANDIDA RUGOSA LIPASE IMMOBILIZED ONTO LAYERED DOUBLE HYDROXIDES AS CATALYST IN SYNTHESIS OF FATTY ACID ESTERS

2016 ◽  
Vol 78 (5-6) ◽  
Author(s):  
Mohd Basyaruddin Abdul Rahman ◽  
Siti Salhah Othman ◽  
Noor Mona Md Yunus
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Chain Length ◽  
Candida Rugosa ◽  
Candida Rugosa Lipase ◽  
Carbon Chain ◽  
Fatty Acid Esters ◽  
Carbon Chain Length ◽  
Chain Lengths ◽  
Acid Esters

The enzymatic selectivity of Lipase from Candida rugosa immobilized onto a calcined layered double hydroxide (CLDHs-CRL) towards the chain-length of fatty acids and alcohols in the synthesis of fatty acid esters was investigated.  The results showed that CMAN-CRL catalyzed the esterification process with fatty acids of medium chain lengths (C10-C14) effectively while, CNAN-CRL and CZAN-CRL exhibited high percentage conversion in fatty acids with carbon chain lengths of C8-C12 and C10-C18, respectively. In the alcohol selectivity study, CMAN-CRL showed high selectivity toward alcohols with carbon chain lengths of C4, C6 and C10.  On the other hand, both CNAN-CRL and CZAN-CRL exhibited rather low selectivity towards longer carbon chain length of alcohols. 

Influence of Carbon Chain Length and Unsaturation on the Esterification Activity of Fatty Acids on Nb2O5Catalyst

2009 ◽  
Vol 48 (24) ◽  
pp. 10816-10819 ◽  
Author(s):  
Kalaru Srilatha ◽  
N. Lingaiah ◽  
Potharaju S. Sai Prasad ◽  
B. L. A. Prabhavathi Devi ◽  
R. B. N. Prasad ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Chain Length ◽  
Carbon Chain ◽  
Carbon Chain Length ◽  
Esterification Activity

Carbon Chain Length Modulates MDA‐MB‐231 Breast Cancer Cell Killing Mechanisms by Mitochondrially Targeted Aryl−Urea Fatty Acids

ChemMedChem ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. 247-255
Author(s):  
Michael Murray ◽  
Ariane Roseblade ◽  
Yongjuan Chen ◽  
Kirsi Bourget ◽  
Tristan Rawling
Keyword(s):  
Breast Cancer ◽  
Fatty Acids ◽  
Chain Length ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Carbon Chain ◽  
Cell Killing ◽  
Carbon Chain Length

The formation and destruction of pentenes during the combustion of pentane

1978 ◽  
Vol 364 (1716) ◽  
pp. 75-88 ◽  
Keyword(s):  
Chain Length ◽  
Sharp Decrease ◽  
Carbon Chain ◽  
Carbon Chain Length ◽  
Reactivity Ratios ◽  
Direct Products ◽  
Specific Activities ◽  
Kinetics Of ◽  
Quantitative Importance

Studies have been made of the quantitative rôle of pent-1-ene and pent-2-ene in the combustion of pentane at temperatures below 400°C. The present results show that, under these conditions, pentenes are initial and direct products of pentane combustion and pent-2-ene is the principal conjugate alkene formed [1- 14 C]Pent-1-ene and [2- 14 C]pent-2-ene have been synthesized and the combustion of pentane has also been investigated in the presence of small concentrations of these specifically labelled com­pounds; control experiments have shown that the pentenes, in the amounts added, do not interfere appreciably with the kinetics of pentane combustion. Measurements of the variation with time of the specific activities and concentrations of the pentenes enable the separate rates of formation and destruction of the conjugate alkenes to be determined. Hence it is possible to calculate the total quantities of these compounds formed at different stages of reaction and to show to what extent these are greater than the net amounts revealed by conventional analytical measurements; the differences are found to be most marked at small conversions. The reactivity ratios of pentane and the pentenes have also been determined. The rates of destruction of both pentenes are much greater than that of pentane; pent-2-ene is removed from the system roughly twice as fast as pent-1-ene. An important contrast between the behaviour of pentane and butane is that, between 300 and 400°C, but-1-ene is a much more abundant product than but-2-ene. However, with both alkanes, the relative amounts of the alk-1-enes formed become greater as the temperature is increased; indeed, the rate of formation of pent-1-ene considerably exceeds that of pent-2-ene at the instant of the passage of a strong cool flame. Comparison of the total amounts of conjugate alkenes formed from the two alkanes at 315°C shows that only ca . 30% of the pentane consumed is converted to pentenes, whereas nearly 75% of the butane which has reacted is converted to butenes. Thus there is clearly a sharp decrease in the quantitative importance of conjugate alkenes as the carbon chain length is increased from C 4 to C 5 . This suggests that the predominant reaction of pentyl radicals, under the conditions used, is to add on oxygen to form pentylperoxy radicals.

Induction by perfluorinated fatty acids with different carbon chain length of peroxisomal β-oxidation in the liver of rats

2000 ◽  
Vol 124 (2) ◽  
pp. 119-132 ◽  
Author(s):  
Naomi Kudo ◽  
Naoki Bandai ◽  
Erika Suzuki ◽  
Masanori Katakura ◽  
Yoichi Kawashima
Keyword(s):  
Fatty Acids ◽  
Chain Length ◽  
Carbon Chain ◽  
Carbon Chain Length

scholarly journals Polyenoic very-long-chain fatty acids mobilize intracellular calcium from a thapsigargin-insensitive pool in human neutrophils. The relationship between Ca2+ mobilization and superoxide production induced by long- and very-long-chain fatty acids

1995 ◽  
Vol 311 (2) ◽  
pp. 689-697 ◽  
Author(s):  
S J Hardy ◽  
B S Robinson ◽  
A Ferrante ◽  
C S T Hii ◽  
D W Johnson ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Chain Length ◽  
Carbon Chain ◽  
Superoxide Production ◽  
Human Neutrophils ◽  
Carbon Chain Length ◽  
Long Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids

Fatty acids with more than 22 carbon atoms (very-long-chain fatty acids; VLCFAs) are normal cellular components that have been implicated in the pathophysiology of a number of peroxisomal disorders. To date, however, essentially nothing is known regarding their biological activities. Ca2+ mobilization is an important intracellular signalling system for a variety of agonists and cell types. Given that several polyunsaturated long-chain fatty acids mobilize intracellular Ca2+ and that we have postulated that the VLCFAs may be involved in signal transduction, we examined whether the tetraenoic VLCFA induced Ca2+ mobilization in human neutrophils. We report that fatty acid-induced intracellular Ca2+ mobilization declined for fatty acid species of more than 20 carbon atoms, but increased again as the carbon chain length approached 30. This Ca2+ mobilization occurred independently of inositol 1,4,5-triphosphate production and protein kinase C translocation and involved both the release of Ca2+ from the intracellular stores and changes to the influx or efflux of the ion. We further observed that triacontatetraenoic acid [30:4(n-6)] mobilized Ca2+ from a thapsigargin-insensitive intracellular pool distinct from the thapsigargin-sensitive pools affected by arachidonic acid [20:4(n - 6)] or N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP). 20:4 (n - 6) induced strong superoxide production (chemiluminescence) which was inhibited by thapsigargin pretreatment. In contrast, fatty acid-induced superoxide production progressively declined as the carbon chain length increased beyond 20-22 carbon atoms. Further studies suggested that the thapsigargin-insensitive Ca2+ mobilization elicited by 30:4 (n - 6) was not related to oxyradical formation, while the thapsigargin-sensitive Ca2+ mobilization induced by 20:4 (n - 6) may be involved in the initiation but not necessarily the maintenance of superoxide production. In conclusion, this is the first report to demonstrate a biological activity for the VLCFA and indicates that 30:4 (n - 6) influences second messenger systems in intact cells that differ from those affected by long-chain fatty acids such as 20:4 (n - 6).

scholarly journals Effect of Carbon Chain Length of Fatty Acids on Ketogenesis in the Ruminant

1968 ◽  
Vol 51 (7) ◽  
pp. 1094-1097 ◽  
Author(s):  
S. Yamdagni ◽  
L.H. Schultz ◽  
H.D. Radloff
Keyword(s):  
Fatty Acids ◽  
Chain Length ◽  
Carbon Chain ◽  
Carbon Chain Length
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