Biliary excretion and enterohepatic recycling of proscillaridin a after oral administration to man

1977 ◽  
Vol 11 (4) ◽  
pp. 273-276 ◽  
Author(s):  
K. -E. Andersson ◽  
B. Bergdahl ◽  
G. Wettrell
Keyword(s):  
Oral Administration ◽  
Biliary Excretion ◽  
Enterohepatic Recycling ◽  
Proscillaridin A

Ursodeoxycholic Acid Complexation with 2-Hydroxypropyl-β-Cyclodextrin Increases Ursodeoxycholic Acid Biliary Excretion after Single Oral Administration in Rats

Pharmacology ◽  
2001 ◽  
Vol 62 (2) ◽  
pp. 107-112 ◽  
Author(s):  
Paolo Ventura ◽  
Rossana Panini ◽  
Giuliana Montosi ◽  
Cinzia Garuti ◽  
Maria Vandelli ◽  
...  
Keyword(s):  
Oral Administration ◽  
Ursodeoxycholic Acid ◽  
Biliary Excretion ◽  
Single Oral Administration

Enterohepatic recirculation of oestriol: inhibition by activated charcoal

1986 ◽  
Vol 113 (1) ◽  
pp. 93-95 ◽  
Author(s):  
G. M. Heimer ◽  
D. E. Englund
Keyword(s):  
Oral Administration ◽  
Postmenopausal Women ◽  
Activated Charcoal ◽  
Plasma Concentrations ◽  
Enterohepatic Recirculation ◽  
Elevated Plasma ◽  
Enterohepatic Recycling ◽  
Specific Radioimmunoassay ◽  
Prolonged Effect

Abstract. We have earlier reported on a prolonged effect of orally administered oestriol caused by its enterohepatic recycling after reabsorption from the intestine. The aim of the present study was to test if oral administration of activated charcoal could inhibit the enterohepatic recirculation of orally given oestriol. Plasma concentrations of unconjugated oestriol were measured using a specific radioimmunoassay (RIA). Twelve mg oestriol administered orally to postmenopausal women resulted in elevated plasma oestriol levels for more than 24 h. Plasma oestriol fluctuations in relation to meals were seen. When activated charcoal was given 3 h after oestriol administration, the plasma oestriol concentration declined without further fluctuations and returned to the pretreatment value within 6 h. Our data indicate that oestriol given orally undergoes enterohepatic recirculation after reabsorption from the intestine since administration of charcoal, which binds steroids, resulted in a rapidly declining oestriol level. It is concluded that the prolonged oestriol elevation, which is normally seen, is caused by enterohepatic recycling.

Pharmacokinetics of Salazosulfapyridine (Sulfasalazine, SASP). (III). Metabolism and biliary excretion of SASP in the rat after a single intravenous or oral administration.

1991 ◽  
Vol 6 (3) ◽  
pp. 457-473
Author(s):  
Birgitta SJÖQUIST ◽  
Nils-Otto AHNFELT ◽  
Stig ANDERSSON ◽  
Roland d'ARGY ◽  
Masanori HATSUOKA ◽  
...  
Keyword(s):  
Oral Administration ◽  
Biliary Excretion
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