Hypoxia and hypercapnia in asphyctic differentiation of regional sympathetic activity in the anesthetized rabbit

1971 ◽  
Vol 328 (2) ◽  
pp. 91-102 ◽  
Author(s):  
M. Iriki ◽  
K. Pleschka ◽  
O. -E. Walther ◽  
E. Simon
Keyword(s):  
Sympathetic Activity ◽  
Regional Sympathetic Activity

Regional sympathetic activity, severity of liver disease and hemodynamics in patients with cirrhosis

1991 ◽  
Vol 13 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Christophe Gaudin ◽  
Alain Braillon ◽  
Jorge Luis Poo ◽  
Richard Moreau ◽  
Antoine Hadengue ◽  
...  
Keyword(s):  
Liver Disease ◽  
Sympathetic Activity ◽  
Regional Sympathetic Activity

Regional sympathetic activity in pre-hypertensive phase of spontaneously hypertensive rats

Life Sciences ◽  
1998 ◽  
Vol 62 (12) ◽  
pp. 1111-1118 ◽  
Author(s):  
Aderville Cabassi ◽  
Simonetta Vinci ◽  
Massimo Calzolari ◽  
Giacomo Bruschi ◽  
Alberico Borghetti
Keyword(s):  
Sympathetic Activity ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Regional Sympathetic Activity ◽  
Hypertensive Phase

scholarly journals Possibilities of single-photon emission computed tomography for the assessment of cardiac global and regional sympathetic activity in patients with atrial fibrillation

2019 ◽  
Vol 23 (3) ◽  
pp. 57
Author(s):  
S. M. Minin ◽  
N. A. Nikitin ◽  
E. A. Pokushalov ◽  
A. B. Romanov
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Confidence Interval ◽  
Conflict Of Interest ◽  
Paroxysmal Atrial Fibrillation ◽  
Sympathetic Activity ◽  
Persistent Atrial Fibrillation ◽  
Mibg Scintigraphy ◽  
Mibg Uptake ◽  
Regional Sympathetic Activity

<!-- x-tinymce/html --><div><strong>Aim.</strong> To evaluate global and regional sympathetic activity in patients with atrial fibrillation using <sup>123</sup>I-metaiodbenzylguanidine (<sup>123</sup>I-MIBG) scintigraphy before and after catheter ablation.</div><div><strong>Methods.</strong> A total of 45 patients with paroxysmal and persistent atrial fibrillation (mean age, 55 ± 10 years; 44% women) followed up till catheter ablation were included in the study. All study participants underwent <sup>123</sup>I-MIBG scintigraphy within 1–2 days before and 5–7 days after catheter ablation. The global myocardial sympathetic activity was estimated by calculating the ratio of <sup>123</sup>I-MIBG uptake in the heart and mediastinum in the early and delayed phases (H/Me and H/Md), as well as the <sup>123</sup>I-MIBG wash out rate in 4 h (WR). Regional sympathetic activity was estimated by semiquantitative analysis of the 123I-MIBG uptake in the myocardium of the left ventricle.</div><div><strong>Results.</strong> Baseline <sup>123</sup>I-MIBG scintigraphy showed the difference between paroxysmal and persistent atrial fibrillation patients in WR only (19.2 ± 6.4 and 23.9 ± 7.2, respectively; p = 0.03). A statistically significant decrease of H/Md in average of 0.1 (95% confidence interval, 0.02–0.2; p = 0.02) was found in patients with paroxysmal atrial fibrillation, and a decrease of WR in average of 3.7% (95% confidence interval, −7% to −0.4%; p = 0.03) after catheter ablation. No statistically significant changes of H/Md and WR were found in patients with persistent atrial fibrillation after catheter ablation. The analysis of regional 123I-MIBG uptake in the left ventricular myocardium did not show any statistically significant changes in the regional sympathetic activity after catheter ablation compared with that at baseline.</div><div><strong>Conclusion.</strong> The differences in WR only were found between patients with paroxysmal and persistent atrial fibrillation. Significant changes in myocardial sympathetic activity after catheter ablation were found only in patients with paroxysmal atrial fibrillation, a finding that may be associated with a large number of active sympathetic nerve endings in the myocardium compared with patients with persistent atrial fibrillation.</div><div>ClinicalTrials.gov Identifier: NCT02914860</div><div>Received 23 April 2019. Accepted 26 May 2019.</div><div><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</div><div><strong>Funding:</strong> The study is a part of a research project supported of a grant of the Russian Science Foundation No. 17-75-20118.</div>

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