Brain damage in the preterm infant (clinics in developmental medicine no.131)

1995 ◽  
Vol 37 (5) ◽  
pp. 417-417
Author(s):  
M. V. Squier
Keyword(s):  
Preterm Infant ◽  
Brain Damage

scholarly journals Severe Brain Damage in a Moderate Preterm Infant as Complication of Post-COVID-19 Response during Pregnancy

Neonatology ◽  
2021 ◽  
pp. 1-4
Author(s):  
Viktoria Engert ◽  
Celine Siauw ◽  
Annika Stock ◽  
Monika Rehn ◽  
Achim Wöckel ◽  
...  
Keyword(s):  
Preterm Infant ◽  
Brain Damage ◽  
Fetal Development ◽  
Periventricular Leukomalacia ◽  
Intracranial Bleeding ◽  
Current Evidence ◽  
Potential Consequence ◽  
Maternal Infection ◽  
Sars Coronavirus ◽  
Unique Case

Current evidence from the COVID-19 pandemic suggests that neonatal SARS-coronavirus-2 infections usually have a mild course. Data on how maternal infection during pregnancy affects fetal development are scarce. We present the unique case of a moderate preterm infant with intracranial bleeding and periventricular leukomalacia as a potential consequence of post-COVID-19 hyperinflammation during pregnancy.

MAY HYPOCARBIA CAUSE ISCHAEMIC BRAIN DAMAGE IN THE PRETERM INFANT?

The Lancet ◽  
1986 ◽  
Vol 328 (8504) ◽  
pp. 460 ◽  
Author(s):  
Gorm Greisen ◽  
Hanne Munck ◽  
Hans Lou
Keyword(s):  
Preterm Infant ◽  
Brain Damage ◽  
Ischaemic Brain ◽  
Ischaemic Brain Damage

scholarly journals Preventing Brain Injury in the Preterm Infant—Current Controversies and Potential Therapies

2021 ◽  
Vol 22 (4) ◽  
pp. 1671
Author(s):  
Nathanael Yates ◽  
Alistair J. Gunn ◽  
Laura Bennet ◽  
Simerdeep K. Dhillon ◽  
Joanne O. Davidson
Keyword(s):  
Cerebral Palsy ◽  
Brain Injury ◽  
Preterm Infant ◽  
Brain Damage ◽  
Preterm Infants ◽  
Preclinical Studies ◽  
Recombinant Erythropoietin ◽  
Neurological Outcomes ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

Preterm birth is associated with a high risk of morbidity and mortality including brain damage and cerebral palsy. The development of brain injury in the preterm infant may be influenced by many factors including perinatal asphyxia, infection/inflammation, chronic hypoxia and exposure to treatments such as mechanical ventilation and corticosteroids. There are currently very limited treatment options available. In clinical trials, magnesium sulfate has been associated with a small, significant reduction in the risk of cerebral palsy and gross motor dysfunction in early childhood but no effect on the combined outcome of death or disability, and longer-term follow up to date has not shown improved neurological outcomes in school-age children. Recombinant erythropoietin has shown neuroprotective potential in preclinical studies but two large randomized trials, in extremely preterm infants, of treatment started within 24 or 48 h of birth showed no effect on the risk of severe neurodevelopmental impairment or death at 2 years of age. Preclinical studies have highlighted a number of promising neuroprotective treatments, such as therapeutic hypothermia, melatonin, human amnion epithelial cells, umbilical cord blood and vitamin D supplementation, which may be useful at reducing brain damage in preterm infants. Moreover, refinements of clinical care of preterm infants have the potential to influence later neurological outcomes, including the administration of antenatal and postnatal corticosteroids and more accurate identification and targeted treatment of seizures.

Feeding Skills in the Preterm Infant

ASHA Leader ◽  
2010 ◽  
Vol 15 (7) ◽  
pp. 22-23 ◽  
Author(s):  
Steven M. Barlow ◽  
Meredith A. Poore ◽  
Emily A. Zimmerman ◽  
Don S. Finan
Keyword(s):  
Preterm Infant ◽  
Feeding Skills
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